Metvix cream is applied topically and some time later the skin is illuminated with a proprietary red light (630 nm) source (medical lamp 'Aktilite') to activate the photosensitiser.
Metvix is developed by Photocure and Galderma has bought all rights to Metvix.[1]
Approvals and indicationsedit
Interim result of phototherapy for actinic keratosis with Metvix one week after exposure. Patient has light skin and blue eyes.
methyl, aminolevulinate, drug, used, sensitizer, photodynamic, therapy, prodrug, that, metabolized, protoporphyrin, marketed, metvix, clinical, dataahfs, drugs, commultum, consumer, informationatc, codel01xd03, identifiersiupac, name, methyl, amino, oxopentano. Methyl aminolevulinate MAL is a drug used as a sensitizer in photodynamic therapy It is a prodrug that is metabolized to protoporphyrin IX It is marketed as Metvix Methyl aminolevulinateClinical dataAHFS Drugs comMultum Consumer InformationATC codeL01XD03 WHO IdentifiersIUPAC name Methyl 5 amino 4 oxopentanoateCAS Number33320 16 0 YPubChem CID157922DrugBankDB00992 YChemSpider13180320 YUNII585NM85KYMChEMBLChEMBL1096562 NCompTox Dashboard EPA DTXSID3048570Chemical and physical dataFormulaC 6H 11N O 3Molar mass145 158 g mol 13D model JSmol Interactive imageSMILES O C CC N C O OC CInChI InChI 1S C6H11NO3 c1 4 8 3 5 7 6 9 10 2 h5H 3 7H2 1 2H3 YKey FLQHIIVXMKXKFT UHFFFAOYSA N Y N Y what is this verify Metvix cream is applied topically and some time later the skin is illuminated with a proprietary red light 630 nm source medical lamp Aktilite to activate the photosensitiser Metvix is developed by Photocure and Galderma has bought all rights to Metvix 1 Approvals and indications edit nbsp Interim result of phototherapy for actinic keratosis with Metvix one week after exposure Patient has light skin and blue eyes Methyl aminolevulinate is approved in New Zealand for treatment of basal cell carcinoma 2 It is now approved in many countries and has been used to treat non melanoma skin cancer including basal cell carcinoma 3 It has some advantages over Levulan 4 It has been reported as controversial in some quarters with severe pain allegedly being experienced by some patients 5 References edit Photocure Divests Metvix to Galderma for EUR 51 Million Archived from the original on 2011 02 07 Retrieved 2010 09 10 Ngan V 2003 Methyl aminolevulinate photodynamic therapy MAL PDT DermNet NZ New 5 Year Metvix PDT Data Demonstrate Long Term Efficacy amp Reliability For NM Skin Cancer Treatment EurekAlert 2006 O Connor AE Gallagher WM Byrne AT 2009 Porphyrin and nonporphyrin photosensitizers in oncology preclinical and clinical advances in photodynamic therapy Photochemistry and Photobiology 85 5 1053 74 doi 10 1111 j 1751 1097 2009 00585 x PMID 19682322 S2CID 205950773 Concerns raised over ALA skin cancer cream as patients recount horrendous pain Australian Broadcasting Corporation 16 November 2013 nbsp This antineoplastic or immunomodulatory drug article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Methyl aminolevulinate amp oldid 1120099605, wikipedia, wiki, book, books, library,
