Martinotti cells are associated with a cortical dampening mechanism.[4] When the pyramidal neuron, which is the most common type of neuron in the cortex, starts getting overexcited, Martinotti cells start sending inhibitory signals to the surrounding neurons. [5]
Historically, the discovery of Martinotti cells has been mistakenly attributed to Giovanni Martinotti 1888, although it is now accepted that they were actually discovered in 1889 by Carlo Martinotti (1859–1908), a student of Camillo Golgi.[6]
^Wang Y, Toledo-Rodriguez M, Gupta A, et al. (November 2004). "Anatomical, physiological and molecular properties of Martinotti cells in the somatosensory cortex of the juvenile rat". J. Physiol. 561 (Pt 1): 65–90. doi:10.1113/jphysiol.2004.073353. PMC1665344. PMID 15331670.
^Sugino K, Hempel CM, Miller MN, et al. (January 2006). "Molecular taxonomy of major neuronal classes in the adult mouse forebrain". Nat. Neurosci.9 (1): 99–107. doi:10.1038/nn1618. PMID 16369481. S2CID 27815855.
^Hilscher, Markus M.; Leão, Richardson N.; Edwards, Steven J.; Leão, Katarina E.; Kullander, Klas (2017-02-09). "Chrna2-Martinotti Cells Synchronize Layer 5 Type A Pyramidal Cells via Rebound Excitation". PLOS Biology. 15 (2): e2001392. doi:10.1371/journal.pbio.2001392. ISSN 1545-7885. PMC5300109. PMID 28182735.
^Riedemann, T (17 June 2019). "Diversity and Function of Somatostatin-Expressing Interneurons in the Cerebral Cortex". International Journal of Molecular Sciences. 20 (12): 2952. doi:10.3390/ijms20122952. PMC6627222. PMID 31212931.
^Silberberg G, Markram H (March 2007). "Disynaptic inhibition between neocortical pyramidal cells mediated by Martinotti cells". Neuron. 53 (5): 735–46. doi:10.1016/j.neuron.2007.02.012. PMID 17329212. S2CID 15624023.
^Martinotti C (1889). "Contributo allo studio della corteccia cerebrale, ed all'origine centrale dei nervi". Ann. Freniatr. Sci. Affini. 1: 14–381.
This neuroanatomy article is a stub. You can help Wikipedia by expanding it.
martinotti, cell, small, multipolar, neurons, with, short, branching, dendrites, they, scattered, throughout, various, layers, cerebral, cortex, sending, their, axons, cortical, layer, where, they, form, axonal, arborization, arbors, transgress, multiple, colu. Martinotti cells are small multipolar neurons with short branching dendrites They are scattered throughout various layers of the cerebral cortex sending their axons up to the cortical layer I where they form axonal arborization The arbors transgress multiple columns in layer VI and make contacts with the distal tuft dendrites of pyramidal cells 1 Martinotti cells express somatostatin and sometimes calbindin but not parvalbumin or vasoactive intestinal peptide 2 Furthermore Martinotti cells in layer V have been shown to express the nicotinic acetylcholine receptor a2 subunit Chrna2 3 Martinotti cellIdentifiersNeuroLex IDnifext 55Anatomical terms of neuroanatomy edit on Wikidata Martinotti cells are associated with a cortical dampening mechanism 4 When the pyramidal neuron which is the most common type of neuron in the cortex starts getting overexcited Martinotti cells start sending inhibitory signals to the surrounding neurons 5 Historically the discovery of Martinotti cells has been mistakenly attributed to Giovanni Martinotti 1888 although it is now accepted that they were actually discovered in 1889 by Carlo Martinotti 1859 1908 a student of Camillo Golgi 6 Contents 1 External links 1 1 News press releases 2 See also 3 ReferencesExternal links editNews press releases edit Rare cell prevents rampant brain activity on the discovery of potential dampening influence of Martinotti cells NIF Search Martinotti Cell via the Neuroscience Information FrameworkSee also editList of distinct cell types in the adult human bodyReferences edit Wang Y Toledo Rodriguez M Gupta A et al November 2004 Anatomical physiological and molecular properties of Martinotti cells in the somatosensory cortex of the juvenile rat J Physiol 561 Pt 1 65 90 doi 10 1113 jphysiol 2004 073353 PMC 1665344 PMID 15331670 Sugino K Hempel CM Miller MN et al January 2006 Molecular taxonomy of major neuronal classes in the adult mouse forebrain Nat Neurosci 9 1 99 107 doi 10 1038 nn1618 PMID 16369481 S2CID 27815855 Hilscher Markus M Leao Richardson N Edwards Steven J Leao Katarina E Kullander Klas 2017 02 09 Chrna2 Martinotti Cells Synchronize Layer 5 Type A Pyramidal Cells via Rebound Excitation PLOS Biology 15 2 e2001392 doi 10 1371 journal pbio 2001392 ISSN 1545 7885 PMC 5300109 PMID 28182735 Riedemann T 17 June 2019 Diversity and Function of Somatostatin Expressing Interneurons in the Cerebral Cortex International Journal of Molecular Sciences 20 12 2952 doi 10 3390 ijms20122952 PMC 6627222 PMID 31212931 Silberberg G Markram H March 2007 Disynaptic inhibition between neocortical pyramidal cells mediated by Martinotti cells Neuron 53 5 735 46 doi 10 1016 j neuron 2007 02 012 PMID 17329212 S2CID 15624023 Martinotti C 1889 Contributo allo studio della corteccia cerebrale ed all origine centrale dei nervi Ann Freniatr Sci Affini 1 14 381 nbsp This neuroanatomy article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Martinotti cell amp oldid 1205897079, wikipedia, wiki, book, books, library,
