The MYCBP gene encodes a protein that binds to the N-terminal region of MYC (MIM 190080) and stimulates the activation of E box-dependent transcription by MYC.[supplied by OMIM][6]
^ abYukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H (Nov 2002). "AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase". The Journal of Biological Chemistry. 277 (47): 45480–92. doi:10.1074/jbc.M206201200. PMID 12223483.
^Furusawa M, Ohnishi T, Taira T, Iguchi-Ariga SM, Ariga H (Sep 2001). "AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP-dependent protein kinase". The Journal of Biological Chemistry. 276 (39): 36647–51. doi:10.1074/jbc.M103885200. PMID 11483602.
Further readingedit
Furusawa M, Ohnishi T, Taira T, Iguchi-Ariga SM, Ariga H (Sep 2001). "AMY-1, a c-Myc-binding protein, is localized in the mitochondria of sperm by association with S-AKAP84, an anchor protein of cAMP-dependent protein kinase". The Journal of Biological Chemistry. 276 (39): 36647–51. doi:10.1074/jbc.M103885200. PMID 11483602.
Yukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H (Aug 2002). "AMAP-1, a novel testis-specific AMY-1-binding protein, is differentially expressed during the course of spermatogenesis". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1577 (1): 126–32. doi:10.1016/s0167-4781(02)00411-6. PMID 12151104.
Yukitake H, Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H (Nov 2002). "AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase". The Journal of Biological Chemistry. 277 (47): 45480–92. doi:10.1074/jbc.M206201200. PMID 12223483.
Furusawa M, Taira T, Iguchi-Ariga SM, Ariga H (Dec 2002). "AMY-1 interacts with S-AKAP84 and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex". The Journal of Biological Chemistry. 277 (52): 50885–92. doi:10.1074/jbc.M206387200. PMID 12414807.
Tomsig JL, Snyder SL, Creutz CE (Mar 2003). "Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif". The Journal of Biological Chemistry. 278 (12): 10048–54. doi:10.1074/jbc.M212632200. PMID 12522145.
Gevaert K, Goethals M, Martens L, Van Damme J, Staes A, Thomas GR, Vandekerckhove J (May 2003). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nature Biotechnology. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801. S2CID 23783563.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Ishizaki R, Shin HW, Iguchi-Ariga SM, Ariga H, Nakayama K (Aug 2006). "AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors". Genes to Cells. 11 (8): 949–59. doi:10.1111/j.1365-2443.2006.00991.x. PMID 16866877. S2CID 36364701.
Sedoris KC, Thomas SD, Miller DM (Jul 2007). "c-myc promoter binding protein regulates the cellular response to an altered glucose concentration". Biochemistry. 46 (29): 8659–68. doi:10.1021/bi7003558. PMID 17595061.
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mycbp, binding, protein, protein, that, humans, encoded, gene, available, structurespdbortholog, search, pdbe, rcsblist, codes2yy0identifiersaliases, binding, proteinexternal, idsomim, 606535, 1891750, homologene, 49312, genecards, gene, location, human, chrom. C Myc binding protein is a protein that in humans is encoded by the MYCBP gene 5 6 MYCBPAvailable structuresPDBOrtholog search PDBe RCSBList of PDB id codes2YY0IdentifiersAliasesMYCBP AMY 1 MYC binding proteinExternal IDsOMIM 606535 MGI 1891750 HomoloGene 49312 GeneCards MYCBPGene location Human Chr Chromosome 1 human 1 Band1p34 3Start38 862 493 bp 1 End38 873 368 bp 1 Gene location Mouse Chr Chromosome 4 mouse 2 Band4 4 D2 2Start123 798 625 bp 2 End123 806 062 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inmonocyterectumright uterine tubebody of pancreasislet of Langerhansright adrenal glandleft adrenal glandbody of stomachminor salivary glandoocyteTop expressed insecondary oocyteolfactory epitheliumseminiferous tubuleyolk sacmorulaconjunctival fornixprimitive streakuretermedullary collecting ductspermatidMore reference expression dataBioGPSn aGene ontologyMolecular functiontranscription coactivator activity protein bindingCellular componentcytoplasm nucleus mitochondrionBiological processregulation of transcription DNA templated transcription DNA templated spermatogenesis positive regulation of nucleic acid templated transcriptionSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez2629256309EnsemblENSG00000214114ENSMUSG00000028647UniProtQ99417Q9EQS3RefSeq mRNA NM 012333NM 019660RefSeq protein NP 036465NP 062634Location UCSC Chr 1 38 86 38 87 MbChr 4 123 8 123 81 MbPubMed search 3 4 WikidataView Edit HumanView Edit Mouse Contents 1 Function 2 Interactions 3 References 4 Further readingFunction editThe MYCBP gene encodes a protein that binds to the N terminal region of MYC MIM 190080 and stimulates the activation of E box dependent transcription by MYC supplied by OMIM 6 Interactions editMYCBP has been shown to interact with AKAP1 7 8 C3orf15 7 and Myc 5 References edit a b c GRCh38 Ensembl release 89 ENSG00000214114 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000028647 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine a b Taira T Maeda J Onishi T Kitaura H Yoshida S Kato H Ikeda M Tamai K Iguchi Ariga SM Ariga H Aug 1998 AMY 1 a novel C MYC binding protein that stimulates transcription activity of C MYC Genes to Cells 3 8 549 65 doi 10 1046 j 1365 2443 1998 00206 x PMID 9797456 a b Entrez Gene MYCBP c myc binding protein a b Yukitake H Furusawa M Taira T Iguchi Ariga SM Ariga H Nov 2002 AAT 1 a novel testis specific AMY 1 binding protein forms a quaternary complex with AMY 1 A kinase anchor protein 84 and a regulatory subunit of cAMP dependent protein kinase and is phosphorylated by its kinase The Journal of Biological Chemistry 277 47 45480 92 doi 10 1074 jbc M206201200 PMID 12223483 Furusawa M Ohnishi T Taira T Iguchi Ariga SM Ariga H Sep 2001 AMY 1 a c Myc binding protein is localized in the mitochondria of sperm by association with S AKAP84 an anchor protein of cAMP dependent protein kinase The Journal of Biological Chemistry 276 39 36647 51 doi 10 1074 jbc M103885200 PMID 11483602 Further reading editFurusawa M Ohnishi T Taira T Iguchi Ariga SM Ariga H Sep 2001 AMY 1 a c Myc binding protein is localized in the mitochondria of sperm by association with S AKAP84 an anchor protein of cAMP dependent protein kinase The Journal of Biological Chemistry 276 39 36647 51 doi 10 1074 jbc M103885200 PMID 11483602 Yukitake H Furusawa M Taira T Iguchi Ariga SM Ariga H Aug 2002 AMAP 1 a novel testis specific AMY 1 binding protein is differentially expressed during the course of spermatogenesis Biochimica et Biophysica Acta BBA Gene Structure and Expression 1577 1 126 32 doi 10 1016 s0167 4781 02 00411 6 PMID 12151104 Yukitake H Furusawa M Taira T Iguchi Ariga SM Ariga H Nov 2002 AAT 1 a novel testis specific AMY 1 binding protein forms a quaternary complex with AMY 1 A kinase anchor protein 84 and a regulatory subunit of cAMP dependent protein kinase and is phosphorylated by its kinase The Journal of Biological Chemistry 277 47 45480 92 doi 10 1074 jbc M206201200 PMID 12223483 Furusawa M Taira T Iguchi Ariga SM Ariga H Dec 2002 AMY 1 interacts with S AKAP84 and AKAP95 in the cytoplasm and the nucleus respectively and inhibits cAMP dependent protein kinase activity by preventing binding of its catalytic subunit to A kinase anchoring protein AKAP complex The Journal of Biological Chemistry 277 52 50885 92 doi 10 1074 jbc M206387200 PMID 12414807 Tomsig JL Snyder SL Creutz CE Mar 2003 Identification of targets for calcium signaling through the copine family of proteins Characterization of a coiled coil copine binding motif The Journal of Biological Chemistry 278 12 10048 54 doi 10 1074 jbc M212632200 PMID 12522145 Gevaert K Goethals M Martens L Van Damme J Staes A Thomas GR Vandekerckhove J May 2003 Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N terminal peptides Nature Biotechnology 21 5 566 9 doi 10 1038 nbt810 PMID 12665801 S2CID 23783563 Rual JF Venkatesan K Hao T Hirozane Kishikawa T Dricot A Li N Berriz GF Gibbons FD Dreze M Ayivi Guedehoussou N Klitgord N Simon C Boxem M Milstein S Rosenberg J Goldberg DS Zhang LV Wong SL Franklin G Li S Albala JS Lim J Fraughton C Llamosas E Cevik S Bex C Lamesch P Sikorski RS Vandenhaute J Zoghbi HY Smolyar A Bosak S Sequerra R Doucette Stamm L Cusick ME Hill DE Roth FP Vidal M Oct 2005 Towards a proteome scale map of the human protein protein interaction network Nature 437 7062 1173 8 Bibcode 2005Natur 437 1173R doi 10 1038 nature04209 PMID 16189514 S2CID 4427026 Ishizaki R Shin HW Iguchi Ariga SM Ariga H Nakayama K Aug 2006 AMY 1 associate of Myc 1 localization to the trans Golgi network through interacting with BIG2 a guanine nucleotide exchange factor for ADP ribosylation factors Genes to Cells 11 8 949 59 doi 10 1111 j 1365 2443 2006 00991 x PMID 16866877 S2CID 36364701 Sedoris KC Thomas SD Miller DM Jul 2007 c myc promoter binding protein regulates the cellular response to an altered glucose concentration Biochemistry 46 29 8659 68 doi 10 1021 bi7003558 PMID 17595061 nbsp This protein related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title MYCBP amp oldid 1170224064, wikipedia, wiki, book, books, library,
