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List of antiviral drugs

Antiviral drugs are different from antibiotics. Flu antiviral drugs are different from antiviral drugs used to treat other infectious diseases such as COVID-19. Antiviral drugs prescribed to treat COVID-19 are not approved or authorized to treat flu.[1]

List of Antiviral Drugs
Antiviral Use Manufacturer Component Type Year approved
Abacavir HIV ViiV Healthcare Nucleoside analogue reverse transcriptase inhibitor (NRTI) 1998
Acyclovir (Aciclovir) Herpes Simplex, chickenpox,[2] varicella zoster virus guanosine analogue RTI 1981
Adefovir Hepatitis B[3] Gilead Sciences RTI 2002 (FDA), 2003 (EU)
Amantadine Influenza Influenza A virus M2 proton channel antagonist
Ampligen Avian Influenza Immunomodulatory double-stranded RNA
Amprenavir (Agenerase) HIV Protease inhibitor (PI)
Umifenovir (Arbidol) Influenza Hemagglutinin inhibitor
Atazanavir HIV PI
Atripla (Efavirenz/emtricitabine/tenofovir) HIV
  • Efavirenz: Non-nucleoside RTI (NNRTI)
  • Emtricitabine: NRTI
  • Tenofovir disoproxil: NRTI
Baloxavir marboxil (Xofluza)[4] Influenza A/B Cap snatching endonuclease inhibitor 2018
Biktarvy (Bictegravir/emtricitabine/tenofovir alafenamide) HIV
  • Bictegravir: INSTI
  • Emtricitabine: NRTI
  • Tenofovir alafenamide: NRTI
Boceprevir Hepatitis C genotype 1[5] Schering-Plough, then Merck Group Protease inhibitor
  • FDA approved 2011
  • Withdrawn 2015
Bulevirtide Hepatitis D/B Sodium/bile acid cotransporter inactivator
Cidofovir AIDS Viral DNA Polymerase inhibitor
Cobicistat (Tybost)[6] HIV human CYP3A protein inhibitor
Combivir (Lamivudine/Zidovudine) HIV
Daclatasvir (Daklinza) Hepatitis C NS5A inhibitor
Darunavir HIV antiretroviral HIV PI
Delavirdine HIV antiretroviral NNRTI
Descovy (Emtricitabine/tenofovir alafenamide) Hepatitis B
  • Emtricitabine: NRTI
  • Tenofovir alafenamide: NRTI
Didanosine HIV Adenosine analogue RTI
Docosanol Herpes Simplex Entry inhibitor
Dolutegravir HIV Integrase inhibitor
Doravirine (Pifeltro)[7] HIV NNRTI
Edoxudine Herpes Simplex Thymidine analogue inhibitor
Efavirenz HIV Mylan NNRTI 1998
Elvitegravir HIV Gilead Sciences Integrase inhibitor
Emtricitabine HIV Gilead Sciences NRTI 2003
Enfuvirtide HIV Entry inhibitor 2003
Ensitrelvir COVID-19 Shionogi 3C-like protease inhibitor
Entecavir HIV NRTI 2005
Etravirine (Intelence)[8] HIV NNRTI 2008
Famciclovir Herpes Zoster Guanosine analogue 1994
Fomivirsen AIDS Anti-sense oligonucleotide Anti-sense
  • FDA-licensed in 1998
  • Withdrawn in EU (2002), US (2006)
Fosamprenavir HIV ViiV Healthcare Amprenavir pro-drug 2003 (FDA), 2004 (EMA)
Foscarnet Herpes Pyrophosphate analogue DNA polymerase inhibitor 1991
Ganciclovir (Cytovene)[9] Cytomegalovirus (CMV)[10] Competitive nucleoside analogue dGTP inhibitor 1988
Ibacitabine Herpes labialis
Ibalizumab (Trogarzo)[11] HIV Entry inhibitor 2018
Idoxuridine Herpes dU analogue inhibitor 1962
Imiquimod Genital wart, Basal cell carcinoma, Actinic keratosis Opioid growth factor receptor (OGFr) agonist 1997
Inosine pranobex Herpes Simplex Thymus hormone immunostimulant
Indinavir HIV PI 1996
Lamivudine HIV cytidine analogue RTI
Letermovir (Prevymis)[12] Cytomegalovirus (CMV)
Lopinavir HIV
Loviride HIV
Maraviroc HIV entry inhibitor
Methisazone Smallpox
Moroxydine Influenza
Nelfinavir HIV
Nirmatrelvir/ritonavir (Paxlovid) COVID-19 Pfizer 3C-like protease inhibitor (Nirmatrelvir) / inhibition of metabolism of nirmatrelvir (ritonavir)
Nevirapine HIV non-nucleoside reverse transcriptase inhibitor
Nitazoxanide Broad-spectrum antiviral thiazolide
Norvir HIV
Oseltamivir (Tamiflu)[13] Influenza neuraminidase inhibitor
Penciclovir Herpes
Peramivir Influenza
Penciclovir Herpes
Peramivir (Rapivab)[14] Influenza
Pleconaril Picornavirus Schering-Plough
Podophyllotoxin Genital wart
Raltegravir HIV Integrase inhibitor
Remdesivir COVID-19 viral RNA polymerase inhibitor
Ribavirin Hepatitis C[15] nucleoside analogue reverse transcriptase inhibitor
Rilpivirine (Edurant)[16] HIV
Rilpivirine HIV
Rimantadine Influenza A M2 proton channel antagonist
Ritonavir HIV HIV-1 protease inhibitor
Saquinavir HIV
Simeprevir (Olysio) Hepatitis C
Sofosbuvir Hepatitis C[17] nucleoside analogue reverse transcriptase inhibitor
Stavudine HIV
Taribavirin (Viramidine) Hepatitis Syndromes in which Ribavirin is active[18]
Telaprevir Hepatitis C
Telbivudine (Tyzeka) Hepatitis B
Tenofovir alafenamide Hepatitis B
Tenofovir disoproxil Hepatitis B, HIV[19]
Tipranavir HIV
Trifluridine Eyes related Herpes
Trizivir HIV
Tromantadine Herpes Simplex
Truvada HIV
Umifenovir Influenza
Valaciclovir (Valtrex)[20] Herpes Simplex/Zoster
Valganciclovir (Valcyte)[21] Cytomegalovirus (CMV)
Vicriviroc HIV-1 Schering-Plough pyrimidine CCR5 entry inhibitor
Vidarabine Herpes Simplex, Varicella Zoster
Zalcitabine HIV
Zanamivir (Relenza)[22] Influenza A, Influenza B
Zidovudine HIV[23] Antiretroviral


References edit

  1. ^ "What You Should Know about Flu Antiviral Drugs". 15 December 2022.
  2. ^ "Acyclovir". The American Society of Health-System Pharmacists. from the original on 2015-01-05. Retrieved Jan 1, 2015.
  3. ^ Marcellin P, Chang TT, Lim SG, Tong MJ, Sievert W, Shiffman ML, et al. (February 2003). "Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B". The New England Journal of Medicine. 348 (9): 808–16. doi:10.1056/NEJMoa020681. PMID 12606735.
  4. ^ "Xofluza- baloxavir marboxil tablet, film coated". DailyMed. 28 October 2019. Retrieved 21 September 2020.
  5. ^ Degertekin B, Lok AS (May 2008). "Update on viral hepatitis: 2007". Curr. Opin. Gastroenterol. 24 (3): 306–11. doi:10.1097/MOG.0b013e3282f70285. PMID 18408458. S2CID 43762307
  6. ^ "Tybost- cobicistat tablet, film coated". DailyMed. 27 August 2020. Retrieved 21 September 2020.
  7. ^ "Pifeltro- doravirine tablet, film coated". DailyMed. 10 October 2019. Retrieved 21 September 2020.
  8. ^ "Intelence- etravirine tablet". DailyMed. 9 June 2020. Retrieved 21 September 2020.
  9. ^ "Cytovene IV- ganciclovir sodium injection, powder, lyophilized, for solution". DailyMed. 19 June 2020. Retrieved 21 September 2020.
  10. ^ Rossi S, editor. Australian Medicines Handbook 2006. Adelaide: Australian Medicines Handbook; 2006. ISBN 0-9757919-2-3
  11. ^ "Trogarzo- ibalizumab injection, solution". DailyMed. 8 April 2020. Retrieved 21 September 2020.
  12. ^ "Prevymis- letermovir tablet, film coated PREVYMIS- letermovir injection, solution". DailyMed. 23 March 2020. Retrieved 21 September 2020.
  13. ^ "Tamiflu- oseltamivir phosphate capsule TAMIFLU- oseltamivir phosphate powder, for suspension". DailyMed. Retrieved 21 September 2020.
  14. ^ "Rapivab- peramivir solution". DailyMed. 3 August 2020. Retrieved 21 September 2020.
  15. ^ "Rebetol, Ribasphere (ribavirin) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 28 February 2014. Retrieved 23 February 2014.
  16. ^ "Edurant- rilpivirine hydrochloride tablet, film coated". DailyMed. 8 June 2020. Retrieved 21 September 2020.
  17. ^ Berden FA, Kievit W, Baak LC, Bakker CM, Beuers U, Boucher CA, Brouwer JT, Burger DM, van Erpecum KJ, van Hoek B, Hoepelman AI, Honkoop P, Kerbert-Dreteler MJ, de Knegt RJ, Koek GH, van Nieuwkerk CM, van Soest H, Tan AC, Vrolijk JM, Drenth JP (October 2014). "Dutch guidance for the treatment of chronic hepatitis C virus infection in a new therapeutic era". The Netherlands Journal of Medicine. 72 (8): 388–400. PMID 25387551.
  18. ^ Gish RG (January 2006). "Treating HCV with ribavirin analogues and ribavirin-like molecules". The Journal of Antimicrobial Chemotherapy. 57 (1): 8–13. doi:10.1093/jac/dki405. PMID 16293677
  19. ^ "Tenofovir Disoproxil Fumarate". The American Society of Health-System Pharmacists. Archived from the original on 30 November 2016. Retrieved 29 November 2016.
  20. ^ "Valtrex- valacyclovir hydrochloride tablet, film coated". DailyMed. 10 December 2019. Retrieved 21 September 2020.
  21. ^ "Valcyte- valganciclovir tablet, film coated VALCYTE- valganciclovir hydrochloride powder, for solution". DailyMed. 9 August 2018. Retrieved 3 September 2022.
  22. ^ "Relenza- zanamivir powder". DailyMed. 21 June 2018. Retrieved 21 September 2020.
  23. ^ "Zidovudine". PubChem Public Chemical Database. NCBI. from the original on October 25, 2012. Retrieved April 10, 2011.

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Antiviral drugs are different from antibiotics Flu antiviral drugs are different from antiviral drugs used to treat other infectious diseases such as COVID 19 Antiviral drugs prescribed to treat COVID 19 are not approved or authorized to treat flu 1 This article has multiple issues Please help improve it or discuss these issues on the talk page Learn how and when to remove these template messages This article needs to be updated Please help update this article to reflect recent events or newly available information August 2020 This article needs additional citations for verification Please help improve this article by adding citations to reliable sources Unsourced material may be challenged and removed Find sources List of antiviral drugs news newspapers books scholar JSTOR August 2020 Learn how and when to remove this template message Learn how and when to remove this template message List of Antiviral Drugs Antiviral Use Manufacturer Component Type Year approvedAbacavir HIV ViiV Healthcare Nucleoside analogue reverse transcriptase inhibitor NRTI 1998Acyclovir Aciclovir Herpes Simplex chickenpox 2 varicella zoster virus guanosine analogue RTI 1981Adefovir Hepatitis B 3 Gilead Sciences RTI 2002 FDA 2003 EU Amantadine Influenza Influenza A virus M2 proton channel antagonistAmpligen Avian Influenza Immunomodulatory double stranded RNAAmprenavir Agenerase HIV Protease inhibitor PI Umifenovir Arbidol Influenza Hemagglutinin inhibitorAtazanavir HIV PIAtripla Efavirenz emtricitabine tenofovir HIV Efavirenz Non nucleoside RTI NNRTI Emtricitabine NRTI Tenofovir disoproxil NRTIBaloxavir marboxil Xofluza 4 Influenza A B Cap snatching endonuclease inhibitor 2018Biktarvy Bictegravir emtricitabine tenofovir alafenamide HIV Bictegravir INSTI Emtricitabine NRTI Tenofovir alafenamide NRTIBoceprevir Hepatitis C genotype 1 5 Schering Plough then Merck Group Protease inhibitor FDA approved 2011 Withdrawn 2015Bulevirtide Hepatitis D B Sodium bile acid cotransporter inactivatorCidofovir AIDS Viral DNA Polymerase inhibitorCobicistat Tybost 6 HIV human CYP3A protein inhibitorCombivir Lamivudine Zidovudine HIV Lamivudine cytidine analogue RTI Zidovudine thymidine analogue RTIDaclatasvir Daklinza Hepatitis C NS5A inhibitorDarunavir HIV antiretroviral HIV PIDelavirdine HIV antiretroviral NNRTIDescovy Emtricitabine tenofovir alafenamide Hepatitis B Emtricitabine NRTI Tenofovir alafenamide NRTIDidanosine HIV Adenosine analogue RTIDocosanol Herpes Simplex Entry inhibitorDolutegravir HIV Integrase inhibitorDoravirine Pifeltro 7 HIV NNRTIEdoxudine Herpes Simplex Thymidine analogue inhibitorEfavirenz HIV Mylan NNRTI 1998Elvitegravir HIV Gilead Sciences Integrase inhibitor 2012 Fixed dose combo Stribild 2014 single pill 2015 Genvoya Emtricitabine HIV Gilead Sciences NRTI 2003Enfuvirtide HIV Entry inhibitor 2003Ensitrelvir COVID 19 Shionogi 3C like protease inhibitorEntecavir HIV NRTI 2005Etravirine Intelence 8 HIV NNRTI 2008Famciclovir Herpes Zoster Guanosine analogue 1994Fomivirsen AIDS Anti sense oligonucleotide Anti sense FDA licensed in 1998 Withdrawn in EU 2002 US 2006 Fosamprenavir HIV ViiV Healthcare Amprenavir pro drug 2003 FDA 2004 EMA Foscarnet Herpes Pyrophosphate analogue DNA polymerase inhibitor 1991Ganciclovir Cytovene 9 Cytomegalovirus CMV 10 Competitive nucleoside analogue dGTP inhibitor 1988Ibacitabine Herpes labialisIbalizumab Trogarzo 11 HIV Entry inhibitor 2018Idoxuridine Herpes dU analogue inhibitor 1962Imiquimod Genital wart Basal cell carcinoma Actinic keratosis Opioid growth factor receptor OGFr agonist 1997Inosine pranobex Herpes Simplex Thymus hormone immunostimulantIndinavir HIV PI 1996Lamivudine HIV cytidine analogue RTILetermovir Prevymis 12 Cytomegalovirus CMV Lopinavir HIVLoviride HIVMaraviroc HIV entry inhibitorMethisazone SmallpoxMoroxydine InfluenzaNelfinavir HIVNirmatrelvir ritonavir Paxlovid COVID 19 Pfizer 3C like protease inhibitor Nirmatrelvir inhibition of metabolism of nirmatrelvir ritonavir Nevirapine HIV non nucleoside reverse transcriptase inhibitorNitazoxanide Broad spectrum antiviral thiazolideNorvir HIVOseltamivir Tamiflu 13 Influenza neuraminidase inhibitorPenciclovir HerpesPeramivir InfluenzaPenciclovir HerpesPeramivir Rapivab 14 InfluenzaPleconaril Picornavirus Schering PloughPodophyllotoxin Genital wartRaltegravir HIV Integrase inhibitorRemdesivir COVID 19 viral RNA polymerase inhibitorRibavirin Hepatitis C 15 nucleoside analogue reverse transcriptase inhibitorRilpivirine Edurant 16 HIVRilpivirine HIVRimantadine Influenza A M2 proton channel antagonistRitonavir HIV HIV 1 protease inhibitorSaquinavir HIVSimeprevir Olysio Hepatitis CSofosbuvir Hepatitis C 17 nucleoside analogue reverse transcriptase inhibitorStavudine HIVTaribavirin Viramidine Hepatitis Syndromes in which Ribavirin is active 18 Telaprevir Hepatitis CTelbivudine Tyzeka Hepatitis BTenofovir alafenamide Hepatitis BTenofovir disoproxil Hepatitis B HIV 19 Tipranavir HIVTrifluridine Eyes related HerpesTrizivir HIVTromantadine Herpes SimplexTruvada HIVUmifenovir InfluenzaValaciclovir Valtrex 20 Herpes Simplex ZosterValganciclovir Valcyte 21 Cytomegalovirus CMV Vicriviroc HIV 1 Schering Plough pyrimidine CCR5 entry inhibitorVidarabine Herpes Simplex Varicella ZosterZalcitabine HIVZanamivir Relenza 22 Influenza A Influenza BZidovudine HIV 23 AntiretroviralReferences edit What You Should Know about Flu Antiviral Drugs 15 December 2022 Acyclovir The American Society of Health System Pharmacists Archived from the original on 2015 01 05 Retrieved Jan 1 2015 Marcellin P Chang TT Lim SG Tong MJ Sievert W Shiffman ML et al February 2003 Adefovir dipivoxil for the treatment of hepatitis B e antigen positive chronic hepatitis B The New England Journal of Medicine 348 9 808 16 doi 10 1056 NEJMoa020681 PMID 12606735 Xofluza baloxavir marboxil tablet film coated DailyMed 28 October 2019 Retrieved 21 September 2020 Degertekin B Lok AS May 2008 Update on viral hepatitis 2007 Curr Opin Gastroenterol 24 3 306 11 doi 10 1097 MOG 0b013e3282f70285 PMID 18408458 S2CID 43762307 Tybost cobicistat tablet film coated DailyMed 27 August 2020 Retrieved 21 September 2020 Pifeltro doravirine tablet film coated DailyMed 10 October 2019 Retrieved 21 September 2020 Intelence etravirine tablet DailyMed 9 June 2020 Retrieved 21 September 2020 Cytovene IV ganciclovir sodium injection powder lyophilized for solution DailyMed 19 June 2020 Retrieved 21 September 2020 Rossi S editor Australian Medicines Handbook 2006 Adelaide Australian Medicines Handbook 2006 ISBN 0 9757919 2 3 Trogarzo ibalizumab injection solution DailyMed 8 April 2020 Retrieved 21 September 2020 Prevymis letermovir tablet film coated PREVYMIS letermovir injection solution DailyMed 23 March 2020 Retrieved 21 September 2020 Tamiflu oseltamivir phosphate capsule TAMIFLU oseltamivir phosphate powder for suspension DailyMed Retrieved 21 September 2020 Rapivab peramivir solution DailyMed 3 August 2020 Retrieved 21 September 2020 Rebetol Ribasphere ribavirin dosing indications interactions adverse effects and more Medscape Reference WebMD Archived from the original on 28 February 2014 Retrieved 23 February 2014 Edurant rilpivirine hydrochloride tablet film coated DailyMed 8 June 2020 Retrieved 21 September 2020 Berden FA Kievit W Baak LC Bakker CM Beuers U Boucher CA Brouwer JT Burger DM van Erpecum KJ van Hoek B Hoepelman AI Honkoop P Kerbert Dreteler MJ de Knegt RJ Koek GH van Nieuwkerk CM van Soest H Tan AC Vrolijk JM Drenth JP October 2014 Dutch guidance for the treatment of chronic hepatitis C virus infection in a new therapeutic era The Netherlands Journal of Medicine 72 8 388 400 PMID 25387551 Gish RG January 2006 Treating HCV with ribavirin analogues and ribavirin like molecules The Journal of Antimicrobial Chemotherapy 57 1 8 13 doi 10 1093 jac dki405 PMID 16293677 Tenofovir Disoproxil Fumarate The American Society of Health System Pharmacists Archived from the original on 30 November 2016 Retrieved 29 November 2016 Valtrex valacyclovir hydrochloride tablet film coated DailyMed 10 December 2019 Retrieved 21 September 2020 Valcyte valganciclovir tablet film coated VALCYTE valganciclovir hydrochloride powder for solution DailyMed 9 August 2018 Retrieved 3 September 2022 Relenza zanamivir powder DailyMed 21 June 2018 Retrieved 21 September 2020 Zidovudine PubChem Public Chemical Database NCBI Archived from the original on October 25 2012 Retrieved April 10 2011 Portals nbsp Medicine nbsp Viruses Retrieved from https en wikipedia org w index php title List of antiviral drugs amp oldid 1183895695, wikipedia, wiki, book, books, library,

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