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Leslie Dutton

Peter Leslie Dutton FRS is a British biochemist, and Eldridge Reeves Johnson Professor of Biochemistry and Biophysics in the Perelman School of Medicine at the University of Pennsylvania.[1][2] He is a 2013 recipient of the John Scott Award for his work on electron transfer, studying the organization of electrons in cells and the mechanisms by which they convert light or oxygen into energy for the cell.[3]

Education edit

Leslie Dutton was born in England. He received a B.Sc. (Honors) in Chemistry at the University of Wales in 1963, and a Ph.D. in Biochemistry at the University of Wales in 1967.[4]

Research edit

In 1968, Leslie Dutton joined the University of Pennsylvania,[3] where he now leads the Dutton lab at the Perelman School of Medicine.[5] He is also Principal Investigator at the Photosynthetic Antenna Research Center.[6]

Dr. Dutton attempts to understand elementary processes of oxidation-reduction and related biological events. Natural enzymes called oxidoreductases are involved in biological functions including gene regulation, signalling, long range electron transfer, energy conversion (in photosynthesis and respiration), atom transport, drug detoxification, and enzyme catalysis. Using physical, chemical and computational methods, the Dutton lab studies oxidoreductases and redox proteins to discover mechanisms of electron transfer over large distances through proteins and understand quantum mechanical electron tunneling theory. Understanding electron tunnelling gives scientists a foundation for investigation of biological redox reactions and their relationship to chemical events such as proton exchange, protein conformation, and energy conversion.[1]

Through their understanding of such processes, Dutton and his lab have been able to manipulate electron transfer in structured highly simplified settings, and create man-made versions of proteins. Such maquettes, simple versions of their highly complex biological counterparts, enable researchers to model the minimal requirements for function. Futuristic applications could include creation of clean energy sources and prevention of genetic and age-related diseases.[3]

Awards and honors edit

  • Fellow of the Royal Society, elected March 15, 1990
  • Eldridge Reeves Johnson Professor, 1991
  • Fellow of the University College, University of Wales, 1994
  • Peter Mitchell Medal, Glynn, 1994
  • Keilin Medal of the Biochemical Society, 1994
  • IBM Partnership Award, 1995[citation needed]
  • John Morgan Society, 1999[citation needed]
  • Senior Visiting Fellowship, St. John's College, Oxford, 2001
  • Frontiers in Biological Chemistry Award: Max Planck Institute Mulheim, Germany, 2002
  • Randolph T. Major Medal: Merck & Company and The University of Connecticut, 2006
  • The First Sir William Dunn Scholar, Cambridge, 2007[7]
  • John Scott Medal, 2013 [2][3]

References edit

  1. ^ a b "P. Leslie Dutton, Ph.D." Department of Biochemistry and Biophysics. Retrieved 21 November 2013.
  2. ^ a b Kreeger, Karen. "Renaissance Biochemist". 15 November 2013. Penn Medicine News Blog. Retrieved 21 November 2013.
  3. ^ a b c d Vitez, Michael (21 November 2013). "3 Phila. medical men to be honored". Philadelphia Inquirer. Retrieved 21 November 2013.
  4. ^ "Peter Leslie Dutton". Synthetic Biology for Learning and Doing (Conference). Retrieved 21 November 2013.
  5. ^ "Peter Leslie Dutton". Perelman School of Medicine. Retrieved 21 November 2013.
  6. ^ . Washington University in St. Louis. Archived from the original on 4 October 2013. Retrieved 21 November 2013.
  7. ^ "P. Leslie Dutton". Pennergy: The Penn Center for Energy Innovation. Retrieved 21 November 2013.

leslie, dutton, peter, british, biochemist, eldridge, reeves, johnson, professor, biochemistry, biophysics, perelman, school, medicine, university, pennsylvania, 2013, recipient, john, scott, award, work, electron, transfer, studying, organization, electrons, . Peter Leslie Dutton FRS is a British biochemist and Eldridge Reeves Johnson Professor of Biochemistry and Biophysics in the Perelman School of Medicine at the University of Pennsylvania 1 2 He is a 2013 recipient of the John Scott Award for his work on electron transfer studying the organization of electrons in cells and the mechanisms by which they convert light or oxygen into energy for the cell 3 Contents 1 Education 2 Research 3 Awards and honors 4 ReferencesEducation editLeslie Dutton was born in England He received a B Sc Honors in Chemistry at the University of Wales in 1963 and a Ph D in Biochemistry at the University of Wales in 1967 4 Research editIn 1968 Leslie Dutton joined the University of Pennsylvania 3 where he now leads the Dutton lab at the Perelman School of Medicine 5 He is also Principal Investigator at the Photosynthetic Antenna Research Center 6 Dr Dutton attempts to understand elementary processes of oxidation reduction and related biological events Natural enzymes called oxidoreductases are involved in biological functions including gene regulation signalling long range electron transfer energy conversion in photosynthesis and respiration atom transport drug detoxification and enzyme catalysis Using physical chemical and computational methods the Dutton lab studies oxidoreductases and redox proteins to discover mechanisms of electron transfer over large distances through proteins and understand quantum mechanical electron tunneling theory Understanding electron tunnelling gives scientists a foundation for investigation of biological redox reactions and their relationship to chemical events such as proton exchange protein conformation and energy conversion 1 Through their understanding of such processes Dutton and his lab have been able to manipulate electron transfer in structured highly simplified settings and create man made versions of proteins Such maquettes simple versions of their highly complex biological counterparts enable researchers to model the minimal requirements for function Futuristic applications could include creation of clean energy sources and prevention of genetic and age related diseases 3 Awards and honors editFellow of the Royal Society elected March 15 1990 Eldridge Reeves Johnson Professor 1991 Fellow of the University College University of Wales 1994 Peter Mitchell Medal Glynn 1994 Keilin Medal of the Biochemical Society 1994 IBM Partnership Award 1995 citation needed John Morgan Society 1999 citation needed Senior Visiting Fellowship St John s College Oxford 2001 Frontiers in Biological Chemistry Award Max Planck Institute Mulheim Germany 2002 Randolph T Major Medal Merck amp Company and The University of Connecticut 2006 The First Sir William Dunn Scholar Cambridge 2007 7 John Scott Medal 2013 2 3 References edit a b P Leslie Dutton Ph D Department of Biochemistry and Biophysics Retrieved 21 November 2013 a b Kreeger Karen Renaissance Biochemist 15 November 2013 Penn Medicine News Blog Retrieved 21 November 2013 a b c d Vitez Michael 21 November 2013 3 Phila medical men to be honored Philadelphia Inquirer Retrieved 21 November 2013 Peter Leslie Dutton Synthetic Biology for Learning and Doing Conference Retrieved 21 November 2013 Peter Leslie Dutton Perelman School of Medicine Retrieved 21 November 2013 P Leslie Dutton Principal Investigator Washington University in St Louis Archived from the original on 4 October 2013 Retrieved 21 November 2013 P Leslie Dutton Pennergy The Penn Center for Energy Innovation Retrieved 21 November 2013 Retrieved from https en wikipedia org w index php title Leslie Dutton amp oldid 1136790636, wikipedia, wiki, book, books, library,

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