Julie Segre

Julie Angela Segre is the Chief and Senior Investigator of the Translational and Functional Genomics Branch in the National Human Genome Research Institute at the National Institutes of Health.^[4] She was elected to the National Academy of Medicine in 2019,^[5] the American Academy of Arts and Sciences in 2020^[6] and the National Academy of Sciences in 2022.^[7]

Julie A. Segre
Julie A. Segre, Ph.D. Senior Investigator, National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH).
Born	Berkeley, California, U.S.
Alma mater	Amherst College MIT
Known for	Foundational studies of the human skin associated microbes (bacteria, fungi, viruses)skin flora^[1] Using DNA sequencing to track antibiotic-resistant bacteria in hospitals. ^[2] NIH 'superbug' was thwarted with help of two scientists ^[3]
Scientific career
Fields	Microbial Genomics Genetics and Molecular Biology
Institutions	National Human Genome Research Institute National Institutes of Health
Academic advisors	Eric Lander, Elaine Fuchs

Early life and education

Segre was born in Berkeley, California, the daughter of Nina and Gino Claudio Segrè. She was raised in Philadelphia, where her father was a professor of physics at the University of Pennsylvania. Segre received her B.A. summa cum laude in mathematics from Amherst College in 1987,^[8] where she later served on the board of trustees.^[9] She received her Ph.D. in 1996 from the Massachusetts Institute of Technology. Segre then performed postdoctoral training in Molecular Genetics and Cell Biology at the University of Chicago (1996-2000).

Research and career

Segre came to the National Human Genome Research Institute of NIH in 2000 and was promoted to a senior investigator with tenure in 2007.^[10]

Segre's laboratory studies how the epidermis interfaces between the body and the environment.^[11] Using genomic methodologies, Segre studies the bacteria and microbes of the skin microbiome.^[11] Segre's laboratory also develops genomic tools to track hospital-acquired infections of multi-drug resistant organisms. ^{[12] [13]}

Medical and research achievements

• 2013 received Service to America Medal^[14][15]
• 2015 elected as a Fellow to the American Academy of Microbiology^[16]
• 2019 elected to the National Academy of Medicine^[17]
• 2020 elected to the American Academy of Arts and Sciences^[18]
• 2022 elected to the National Academy of Sciences^[19]

References

1. Byrd, A. L.; Belkaid, Y.; Segre, J. A. (2018). "The human skin microbiome". Nature Reviews. Microbiology. 16 (3): 143–155. doi:10.1038/nrmicro.2017.157. PMID 29332945. S2CID 46781506.
2. Zimmer, Carl. "How Scientists Stalked a Lethal Superbug—With the Killer's Own DNA". Wired.
3. "NIH 'superbug' was thwarted with help of two scientists". The Washington Post.
4. "Julie Segre biography".
5. "National Academy of Medicine". 21 October 2019.
6. "New Members". American Academy of Arts & Sciences. Retrieved 2020-04-23.
7. "National Academy of Sciences". 3 May 2022.
8. Women in Science at National Institutes of Health 2007-2008. U.S. Department of Health and Human Services. pp. 63–64.
9. "Amherst Trustees".
10. "NHGRI genome.gov".
11. "NIH Intramural Research Program".
12. Johnson, Ryan C.; Deming, Clay; Conlan, Sean; Zellmer, Caroline J.; Michelin, Angela V.; Lee-Lin, Shihqueen; Thomas, Pamela J.; Park, Morgan; Weingarten, Rebecca A.; Less, John; Dekker, John P.; Frank, Karen M.; Musser, Kimberlee A.; McQuiston, John R.; Henderson, David K.; Lau, Anna F.; Palmore, Tara N.; Segre, Julia A. (2018). "Investigation of a Cluster of Sphingomonas koreensis Infections". New England Journal of Medicine. 379 (26): 2529–2539. doi:10.1056/NEJMoa1803238. PMC 6322212. PMID 30586509.
13. "Single-molecule sequencing to track plasmid diversity of hospital-associated carbapenemase-producing Enterobacteriaceae".
14. Samuel J. Heyman Service to America Medals. . Partnership for Public Service. Archived from the original on 2 April 2015. Retrieved 15 March 2015.
15. "Federal 'Employee of the Year' Honorees Hail from NIH".
16. "79 Fellows elected to the American Academy of Microbiology".
17. "National Academy of Medicine". 21 October 2019.
18. "New Members". American Academy of Arts & Sciences. Retrieved 2020-04-23.
19. "National Academy of Sciences". 3 May 2022.

External links

• "Julie Segre - The skin microbiome and chronic disease states". YouTube. NASEM Health and Medicine Division. April 22, 2013.
• "Genomics of Microbes and Microbiomes - Julie Segre (2016)". YouTube. National Human Genome Research Institute. May 19, 2016.
• "Antibiotic Resistant Bacteria". YouTube. American Society for Microbiology. September 1, 2016. (Elizabeth O. King Lecture delivered by J. Segre — discussion of 2011 outbreak of carbapenem-resistant Klebsiella pneumoniae)
• "Julie Segre - In Good Company: Our Microbial Ecosystem in Health and Disease". YouTube. Fondazione Umberto Veronesi. February 8, 2016.
• "Human skin microbiome: trans-kingdom, host-immune interactions - Julie Segre". YouTube. Wellcome Connecting Science Courses and Conferences. December 13, 2018.