Jean M.J. Fréchet (born August 1944) is a French-American chemist and professor emeritus at the University of California, Berkeley. He is best known for his work on polymers including polymer-supported chemistry, chemically amplified photoresists, dendrimers, macroporous separation media, and polymers for therapeutics. Ranked among the top 10 chemists in 2021,[2] he has authored nearly 900 scientific paper and 200 patents including 96 US patents.[3] His research areas include organic synthesis and polymer chemistry applied to nanoscience and nanotechnology with emphasis on the design, fundamental understanding, synthesis, and applications of functional macromolecules.
Fréchet received his first university degree at the Institut de Chimie et Physique Industrielles (now CPE) in Lyon, France, before coming to the US for studies in organic and polymer chemistry under Conrad Schuerch at the State University of New York College of Environmental Science and Forestry, and at Syracuse University (Ph.D. 1971). He was on the Chemistry Faculty at the University of Ottawa in Canada from 1973 to 1987, when he became the IBM Professor of Polymer Chemistry at Cornell University. In 1997 Fréchet joined Chemistry faculty at the University of California, Berkeley and was named the Henry Rapoport Chair of Organic Chemistry in 2003 and Professor of Chemical and Biological Engineering in 2005. From 2010 to 2019 he served as the first Vice President for Research, then Senior Vice-President for Research, Innovation, and Economic Development at the King Abdullah University of Science and Technology.
Researchedit
Fréchet’s early work focused on polymer-supported chemistry with the first approach to the solid-phase synthesis of oligosaccharides [4] and pioneering work on polymeric reagents and polymer protecting groups.[5] In 1979 Working with C.G. Willson at IBM during a sabbatical leave, he invented chemically amplified photoresists [6][7] for micro and nanofabrication. This widely used patented technology [8] which enables the extreme miniaturization of microelectronic devices is now ubiquitous for the fabrication of the very powerful computing and communication equipment in worldwide use. The addition of photogenerated bases [9] led to additional advances in chemically amplified resists. In 1990 working with Craig Hawker at Cornell, he developed the convergent synthesis of dendrimers [10] as well as approaches to hyperbranched polymers.[11] In 1992, working with F. Svec at Cornell, he reported the first preparation of macroporous polymer monoliths [12] that are now used in a variety of chemical separations. Later work at Berkeley saw the development of polymers and dendrimers as carriers for targeted therapeutics [13] and successful approaches to new organic materials for transistors and solar cells.[14]
Honors and awardsedit
2020 National Academy of Engineering Charles Stark Draper Prize in Engineering [15]
2007 Arthur C. Cope Award (American Chemical Society award for outstanding achievement in the field of Organic Chemistry)
2006 Macro Group UK Medal (joint Royal Society for Chemistry and Society of Chemical Industry) for Outstanding Achievement in the field of Macromolecular Chemistry
2005 Esselen Award for Chemistry in the Service of the Public
2005 Chemical Communications 40th Anniversary Award
2004 Docteur de L'Université, Université d'Ottawa, Canada
2003 Henry Rapoport Chair of Organic Chemistry, University of California, Berkeley
2002 Docteur (Honoris Causa), Université de Lyon I, France
2001 American Chemical Society, Salute to Excellence Award
2001 American Chemical Society, A.C. Cope Scholar Award
^"World's Best Chemistry Scientists: H-Index Chemistry Science Ranking".
^"Jean M. J. Frechet Inventions, Patents and Patent Applications – Justia Patents Search".
^Fréchet, J.M.J.; Schuerch, C. Solid-Phase Synthesis of Oligosaccharides. III. Preparation of Some Derivatives of di- and tri- saccharides via a simple Alcoholysis Reaction. Carbohyd. Res., 1972, 22, 399–412
^Fréchet, J.M.J. Synthesis and Applications of Organic Polymers as Supports and Protecting Groups. Tetrahedron, 1981, 37, 663–83
^Fréchet, J.M.J.; Ito, H.; Willson, C.G. Sensitive Deep UV Resist Incorporating Chemical Amplification. Proceedings Microcircuit Engineering 1982, Grenoble, 260–261
^"Patterning the World: The Rise of Chemically Amplified Photoresists". 2 October 2007.
^Ito, H., Willson. C.G., Fréchet, J.M.J Positive and Negative Working Resist Compositions with Acid-Generating Photoinitiator and Polymer with Acid-Labile Groups Pendant From Polymer Backbone. US Patent No. 4,491,628 issued January 1, 1985
^Frechet, J.M.J. Pure & Appl. Chem., 1992, 64, 1239–1248
^Hawker, C.J.; Fréchet, J.M.J. Preparation of Polymers with Controlled Molecular Architecture: A New Convergent Approach to Dendritic Macromolecules. J. Am. Chem. Soc. 1990, 112, 7638–47
^Tomalia, D. A.; Fréchet, J.M. J. Discovery of dendrimers and dendritic polymers: a brief historical perspective. 2002, Journal of Polymer Science, Part A: Polymer Chemistry 40, 2719–2728
^Fox, M.E.; Szoka, F.C.; Fréchet, J.M.J.; Soluble polymer carriers for the treatment of cancer: the importance of molecular architecture. Accounts Chem Res. 2009. 42, 1141–1151
^Beaujuge, P.M.; Frechet, J.M.J. Molecular Design and Ordering Effects in pi-Functional Materials for Transistor and Solar Cell Applications – A Perspective. J. Am. Chem. Soc. 2011, 133, 20009-20029
^"2020 Charles Stark Draper Prize for Engineering Recipients".
^Tobin, Dave. (2013, January 30). "SUNY ESF alumnus Jean Fréchet wins Japan Prize," 2019-01-10 at the Wayback Machine Syracuse.com. Accessed: January 31, 2013.
^"Laureates of the Japan Prize The 2013 (29th) Japan Prize". Japan Prize Foundation. Retrieved 2013-02-13.
^"The Nagoya Medal of Organic Chemistry" (PDF). www.itbm.nagoya-u.ac.jp. Nagoya University. (PDF) from the original on 18 July 2022. Retrieved 27 July 2022.
External linksedit
Berkeley College of Chemistry, Emeriti Faculty, Jean M. J. Fréchet
January 01, 1970
jean, fréchet, this, article, multiple, issues, please, help, improve, discuss, these, issues, talk, page, learn, when, remove, these, template, messages, this, biography, living, person, needs, additional, citations, verification, please, help, adding, reliab. This article has multiple issues Please help improve it or discuss these issues on the talk page Learn how and when to remove these template messages This biography of a living person needs additional citations for verification Please help by adding reliable sources Contentious material about living persons that is unsourced or poorly sourced must be removed immediately from the article and its talk page especially if potentially libelous Find sources Jean Frechet news newspapers books scholar JSTOR February 2013 Learn how and when to remove this message This biographical article is written like a resume Please help improve it by revising it to be neutral and encyclopedic March 2021 Learn how and when to remove this message Jean M J Frechet born August 1944 is a French American chemist and professor emeritus at the University of California Berkeley He is best known for his work on polymers including polymer supported chemistry chemically amplified photoresists dendrimers macroporous separation media and polymers for therapeutics Ranked among the top 10 chemists in 2021 2 he has authored nearly 900 scientific paper and 200 patents including 96 US patents 3 His research areas include organic synthesis and polymer chemistry applied to nanoscience and nanotechnology with emphasis on the design fundamental understanding synthesis and applications of functional macromolecules Jean M J FrechetBorn 1944 08 19 August 19 1944 age 79 Burgundy FranceKnown forDendrimersContributions in the fields of polymer science photolithography molecular self assembly microfluidics and nanotechnology AwardsDickson Prize 2007 Arthur C Cope Award 2007 Japan Prize 2013 King Faisal International Prize 2019 Scientific careerFieldsChemistryInstitutionsKing Abdullah University of Science and TechnologyUniversity of California BerkeleyLawrence Berkeley National LaboratoryCornell UniversityUniversity of OttawaThesisSolid Phase Synthesis of Oligosaccharides 1 1972 Doctoral studentsShelley ClaridgeOther notable studentsCraig HawkerWebsitechemistry wbr berkeley wbr edu wbr faculty wbr chem wbr emeriti wbr frechet www wbr kaust wbr edu wbr sa wbr office vp research jean frechet wbr html Frechet is an elected fellow of the American Association for the Advancement of Science the American Chemical Society and the American Academy of Arts and Sciences and an elected member of the US National Academy of Sciences the US National Academy of Engineering and the Academy of Europe Academia Europaea Contents 1 Education and academic career 2 Research 3 Honors and awards 4 References 5 External linksEducation and academic career editFrechet received his first university degree at the Institut de Chimie et Physique Industrielles now CPE in Lyon France before coming to the US for studies in organic and polymer chemistry under Conrad Schuerch at the State University of New York College of Environmental Science and Forestry and at Syracuse University Ph D 1971 He was on the Chemistry Faculty at the University of Ottawa in Canada from 1973 to 1987 when he became the IBM Professor of Polymer Chemistry at Cornell University In 1997 Frechet joined Chemistry faculty at the University of California Berkeley and was named the Henry Rapoport Chair of Organic Chemistry in 2003 and Professor of Chemical and Biological Engineering in 2005 From 2010 to 2019 he served as the first Vice President for Research then Senior Vice President for Research Innovation and Economic Development at the King Abdullah University of Science and Technology Research editFrechet s early work focused on polymer supported chemistry with the first approach to the solid phase synthesis of oligosaccharides 4 and pioneering work on polymeric reagents and polymer protecting groups 5 In 1979 Working with C G Willson at IBM during a sabbatical leave he invented chemically amplified photoresists 6 7 for micro and nanofabrication This widely used patented technology 8 which enables the extreme miniaturization of microelectronic devices is now ubiquitous for the fabrication of the very powerful computing and communication equipment in worldwide use The addition of photogenerated bases 9 led to additional advances in chemically amplified resists In 1990 working with Craig Hawker at Cornell he developed the convergent synthesis of dendrimers 10 as well as approaches to hyperbranched polymers 11 In 1992 working with F Svec at Cornell he reported the first preparation of macroporous polymer monoliths 12 that are now used in a variety of chemical separations Later work at Berkeley saw the development of polymers and dendrimers as carriers for targeted therapeutics 13 and successful approaches to new organic materials for transistors and solar cells 14 Honors and awards edit2020 National Academy of Engineering Charles Stark Draper Prize in Engineering 15 2019 King Faisal International Prize in Chemistry 16 2013 Japan Prize for the Development of chemically amplified resist polymer materials for innovative semiconductor manufacturing process 17 18 2010 Grand Prix de la Maison de la Chimie Paris 19 2010 Erasmus Medal of the Academia Europaea 20 2010 Society of Polymer Science of Japan International Award for the Development of functional polymers from fundamentals to application 2010 University of California Department of Chemistry Teaching Award 2010 Fellow of the American Chemical Society 2009 Elected to the Academy of Europe Academia Europaea 2009 Nagoya Gold Medal 21 2009 Arun Guthikonda Memorial Award Columbia University 2009 Society of Polymer Science of Japan International Award for the Development of functional polymers from fundamentals to applications 2009 Carothers Award for Outstanding contributions and advances in industrial applications of chemistry 2009 Herman Mark Award American Chemical Society 2008 D Sc Honoris Causa University of Liverpool UK 2007 Dickson Prize in Science Carnegie Mellon University 2007 Arthur C Cope Award American Chemical Society award for outstanding achievement in the field of Organic Chemistry 2006 Macro Group UK Medal joint Royal Society for Chemistry and Society of Chemical Industry for Outstanding Achievement in the field of Macromolecular Chemistry 2005 Esselen Award for Chemistry in the Service of the Public 2005 Chemical Communications 40th Anniversary Award 2004 Docteur de L Universite Universite d Ottawa Canada 2003 Henry Rapoport Chair of Organic Chemistry University of California Berkeley 2002 Docteur Honoris Causa Universite de Lyon I France 2001 American Chemical Society Salute to Excellence Award 2001 American Chemical Society A C Cope Scholar Award 2000 Elected Fellow of the American Academy of Arts and Sciences 2000 Elected Member of the US National Academy of Engineering 2000 Elected Fellow of the PMSE Division of the American Chemical Society 2000 Elected Fellow of the American Association for the Advancement of Science 2000 Elected Member of the US National Academy of Sciences 2000 American Chemical Society ACS Award in Polymer Chemistry 2000 Myron L Bender amp Muriel S Bender Distinguished Summer Lectureship 1999 Society of Imaging Science and Technology Kosar Memorial Award 1996 American Chemical Society ACS Award in Applied Polymer Science 1995 Peter J Debye Chair of Chemistry Cornell University NY 1994 American Chemical Society Cooperative Research Award in Polymer Science 1987 IBM Professor of Polymer Chemistry 1986 American Chemical Society Doolittle Award in Polymer Materials Science amp Engineering 1986 Polymer Society of Japan Lecture Award 1983 IUPAC Canadian National Committee AwardReferences edit WorldCat Accessed January 31 2013 World s Best Chemistry Scientists H Index Chemistry Science Ranking Jean M J Frechet Inventions Patents and Patent Applications Justia Patents Search Frechet J M J Schuerch C Solid Phase Synthesis of Oligosaccharides III Preparation of Some Derivatives of di and tri saccharides via a simple Alcoholysis Reaction Carbohyd Res 1972 22 399 412 Frechet J M J Synthesis and Applications of Organic Polymers as Supports and Protecting Groups Tetrahedron 1981 37 663 83 Frechet J M J Ito H Willson C G Sensitive Deep UV Resist Incorporating Chemical Amplification Proceedings Microcircuit Engineering 1982 Grenoble 260 261 Patterning the World The Rise of Chemically Amplified Photoresists 2 October 2007 Ito H Willson C G Frechet J M J Positive and Negative Working Resist Compositions with Acid Generating Photoinitiator and Polymer with Acid Labile Groups Pendant From Polymer Backbone US Patent No 4 491 628 issued January 1 1985 Frechet J M J Pure amp Appl Chem 1992 64 1239 1248 Hawker C J Frechet J M J Preparation of Polymers with Controlled Molecular Architecture A New Convergent Approach to Dendritic Macromolecules J Am Chem Soc 1990 112 7638 47 Tomalia D A Frechet J M J Discovery of dendrimers and dendritic polymers a brief historical perspective 2002 Journal of Polymer Science Part A Polymer Chemistry 40 2719 2728 Svec F Frechet J M J Novel continuous rods of macroporous polymer as High Performance Liquid Chromatography Separation Media Analytical Chemistry 1992 64 820 822 Fox M E Szoka F C Frechet J M J Soluble polymer carriers for the treatment of cancer the importance of molecular architecture Accounts Chem Res 2009 42 1141 1151 Beaujuge P M Frechet J M J Molecular Design and Ordering Effects in pi Functional Materials for Transistor and Solar Cell Applications A Perspective J Am Chem Soc 2011 133 20009 20029 2020 Charles Stark Draper Prize for Engineering Recipients King Faisal International Prize 2019 Tobin Dave 2013 January 30 SUNY ESF alumnus Jean Frechet wins Japan Prize Archived 2019 01 10 at the Wayback Machine Syracuse com Accessed January 31 2013 Laureates of the Japan Prize The 2013 29th Japan Prize Japan Prize Foundation Retrieved 2013 02 13 Les anciens laureats Academy of Europe Erasmus Medal 2010 The Nagoya Medal of Organic Chemistry PDF www itbm nagoya u ac jp Nagoya University Archived PDF from the original on 18 July 2022 Retrieved 27 July 2022 External links editBerkeley College of Chemistry Emeriti Faculty Jean M J Frechet Retrieved from https en wikipedia org w index php title Jean Frechet amp oldid 1214189560, wikipedia, wiki, book, books, library,
