Iotroxic acid
Iotroxic acid (trade name Biliscopin), used in the form of meglumine iotroxate, is a molecule used as a contrast medium during X-rays.[1][2] It is specifically used during tests looking at the gallbladder and biliary tract.[2] It is given by slow injection into a vein.[2]
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| Trade names | Biliscopin, others |
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| ECHA InfoCard | 100.051.726 |
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| Formula | C22H18I6N2O9 |
| Molar mass | 1215.818 g·mol−1 |
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Side effects are uncommon.[3] They include vomiting, skin flushing, headache, itchiness, and low blood pressure.[2] Rare side effects include seizures and allergic reactions.[2] It should not be used by those who have an iodine allergy.[2] Iotroxic acid is an iodine containing contrast media of the diionic dimer type.[4]
Iotroxic acid was first made in 1976.[5] It is on the World Health Organization's List of Essential Medicines.[6] It is rarely used in the developed world due to the availability of magnetic resonance cholangiopancreatography (MRCP).[7]
References edit
- ^ "Iotroxic Acid". Drugs.com. from the original on 31 December 2016. Retrieved 31 December 2016.
- ^ a b c d e f World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 315, 318. hdl:10665/44053. ISBN 9789241547659.
- ^ Neugebauer E, Sauerland S (2014). "Diagnosis and treatment of common bile duct stones". Recommendations for evidence-based endoscopic surgery: The updated EAES consensus development conferences. Springer Science & Business Media. p. 67. ISBN 9782817808499. from the original on 2017-01-01.
- ^ Schaefer C, Peters PW, Miller RK (2014). "Iodine containing contrast media". Drugs During Pregnancy and Lactation: Treatment Options and Risk Assessment. Academic Press. p. 532. ISBN 9780124079014. from the original on 2017-01-01.
- ^ Korolkovas A (1988). Essentials of Medicinal Chemistry. Wiley. p. 1063. ISBN 9780471883562. from the original on 2017-01-01.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ Sherlock S, Dooley J (2008). "Imaging of the Biliary Tract: Interventional Radiology and Endoscopy". Diseases of the Liver and Biliary System. John Wiley & Sons. p. 568. ISBN 9780470986813. from the original on 2017-01-01.
External links edit
- "Iotroxic Acid". Drug Information Portal. U.S. National Library of Medicine.