Homoisocitric acid

Homoisocitric acid is an isomer of homocitric acid in which the hydroxyl is on the 2 position.^[1] It is an intermediate in the α-aminoadipate pathway of lysine biosynthesis where it is produced by homocitrate synthase and is a substrate for homoaconitase.

Homoisocitric acid

Names
Preferred IUPAC name 1-Hydroxybutane-1,2,4-tricarboxylic acid
Other names 3-Carboxy-2-hydroxyadipic acid
Identifiers
CAS Number	3562-75-2
3D model (JSmol)	Interactive image
ChEBI	CHEBI:29094
ChemSpider	4293958
KEGG	C05662
PubChem CID	5119182
CompTox Dashboard (EPA)	DTXSID80956995
InChI InChI=1S/C7H10O7/c8-4(9)2-1-3(6(11)12)5(10)7(13)14/h3,5,10H,1-2H2,(H,8,9)(H,11,12)(H,13,14) Key: OEJZZCGRGVFWHK-UHFFFAOYSA-N InChI=1/C7H10O7/c8-4(9)2-1-3(6(11)12)5(10)7(13)14/h3,5,10H,1-2H2,(H,8,9)(H,11,12)(H,13,14) Key: OEJZZCGRGVFWHK-UHFFFAOYAM
SMILES O=C(O)CCC(C(=O)O)C(O)C(=O)O
Properties
Chemical formula	C7H10O7
Molar mass	206.150 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Homoisocitrate is an anion, salt, or ester of homoisocitric acid.

See also

• Homoaconitic acid
• Adipic acid

References

1. "Homoisocitric Acid". U.S. National Library of Medicine; National Center for Biotechnology Information.