Homeostatic capacity refers to the capability of systems to self-stabilize in response to external forces or stressors, or more simply the capability of systems to maintain homeostasis.[1][2] For living organisms, it is life's foundational trait, consisting of a hierarchy and network of traits endowed by nature and shaped by natural selection. Homeostatic capacity comprises a multidimensional network of traits and operates at all scales of biology systems levels including molecular, cellular, physiological, and organismal.
In the context of human beings, homeostatic capacity refers to the inherent ability of the body to self-stabilize in response to external and internal stimuli. Homeostatic capacity of the human body erodes with age.[3][4][5]
Homeostatic capacity and agingedit
A hypothesis proffered by the proponents of the Palo Alto Longevity Prize is that the array of ailments associated with aging may be epiphenomena of eroding homeostatic capacity and the process of aging may be halted or reversed by restoring homeostatic capacity to that of a healthy young adult.[6][7][8][9][10]
^"After the last death: Doctors, academics debate the possibility, value of a 150-year lifespan". Palo Alto Online. January 9, 2015. Retrieved January 13, 2015.
^Novoseltsev VN, Novoseltseva J, Yashin AI (2001). "A homeostatic model of oxidative damage explains paradoxes observed in earlier aging experiments: a fusion and extension of older theories of aging". Biogerontology. 2 (2): 127–38. doi:10.1023/a:1011511100472. PMID 11708379. S2CID 6542650.
^Rolls BJ, Phillips PA (March 1990). "Aging and disturbances of thirst and fluid balance". Nutr Rev. 48 (3): 137–44. doi:10.1111/j.1753-4887.1990.tb02915.x. PMID 2406645.
^Phillips, Paddy A.; Hodsman, G. Peter; Johnston, Colin I. (January 1991). "Neuroendocrine mechanisms and cardiovascular homeostasis in the elderly". Cardiovascular Drugs and Therapy. 4 (S6): 1209–1213. doi:10.1007/BF00114221. PMID 2009244. S2CID 32343396.
^Ashlee Vance (September 9, 2014). "Silicon Valley Investor Backs $1 Million Prize to End Death". Bloomberg Businessweek. Retrieved October 1, 2014.
^"$1 Million Longevity Prize Seeks To "Hack The Aging Code"" (Press release). Yahoo! Finance. September 9, 2014. Retrieved October 1, 2014.
^Aaron Kinney (September 14, 2014). "Silicon Valley launches another bid to 'hack' aging, cheat death". San Jose Mercury News. Retrieved October 1, 2014.
^Victoria Thorp (November 23, 2014). "The Palo Alto Prize: A 'Moonshot' at Increasing Longevity". Palo Alto Pulse. Retrieved December 8, 2014.
January 01, 1970
homeostatic, capacity, refers, capability, systems, self, stabilize, response, external, forces, stressors, more, simply, capability, systems, maintain, homeostasis, living, organisms, life, foundational, trait, consisting, hierarchy, network, traits, endowed,. Homeostatic capacity refers to the capability of systems to self stabilize in response to external forces or stressors or more simply the capability of systems to maintain homeostasis 1 2 For living organisms it is life s foundational trait consisting of a hierarchy and network of traits endowed by nature and shaped by natural selection Homeostatic capacity comprises a multidimensional network of traits and operates at all scales of biology systems levels including molecular cellular physiological and organismal Contents 1 Human homeostatic capacity 2 Homeostatic capacity and aging 3 See also 4 ReferencesHuman homeostatic capacity editMain article Human homeostasis In the context of human beings homeostatic capacity refers to the inherent ability of the body to self stabilize in response to external and internal stimuli Homeostatic capacity of the human body erodes with age 3 4 5 Homeostatic capacity and aging editA hypothesis proffered by the proponents of the Palo Alto Longevity Prize is that the array of ailments associated with aging may be epiphenomena of eroding homeostatic capacity and the process of aging may be halted or reversed by restoring homeostatic capacity to that of a healthy young adult 6 7 8 9 10 See also editSenescenceReferences edit Anthony Joonkyoo Yun MD 2014 Hiding in Plain Sight Essays by Joon Yun MD Second Edition p 130 ISBN 9781312492028 After the last death Doctors academics debate the possibility value of a 150 year lifespan Palo Alto Online January 9 2015 Retrieved January 13 2015 Novoseltsev VN Novoseltseva J Yashin AI 2001 A homeostatic model of oxidative damage explains paradoxes observed in earlier aging experiments a fusion and extension of older theories of aging Biogerontology 2 2 127 38 doi 10 1023 a 1011511100472 PMID 11708379 S2CID 6542650 Rolls BJ Phillips PA March 1990 Aging and disturbances of thirst and fluid balance Nutr Rev 48 3 137 44 doi 10 1111 j 1753 4887 1990 tb02915 x PMID 2406645 Phillips Paddy A Hodsman G Peter Johnston Colin I January 1991 Neuroendocrine mechanisms and cardiovascular homeostasis in the elderly Cardiovascular Drugs and Therapy 4 S6 1209 1213 doi 10 1007 BF00114221 PMID 2009244 S2CID 32343396 FAQ Palo Alto Longevity Prize Palo Alto Longevity Prize Retrieved October 1 2014 Ashlee Vance September 9 2014 Silicon Valley Investor Backs 1 Million Prize to End Death Bloomberg Businessweek Retrieved October 1 2014 1 Million Longevity Prize Seeks To Hack The Aging Code Press release Yahoo Finance September 9 2014 Retrieved October 1 2014 Aaron Kinney September 14 2014 Silicon Valley launches another bid to hack aging cheat death San Jose Mercury News Retrieved October 1 2014 Victoria Thorp November 23 2014 The Palo Alto Prize A Moonshot at Increasing Longevity Palo Alto Pulse Retrieved December 8 2014 Retrieved from https en wikipedia org w index php title Homeostatic capacity amp oldid 1169503125, wikipedia, wiki, book, books, library,
