His research focused on thermodynamic linkage analysis of biological macromolecules, addressing the molecular mechanism of cooperative O2 binding to human hemoglobin since the early 1970s. He was a Fellow of the Biophysical Society and one of the founders of the annual Gibbs Conference.[2]
Professor Ackers invented agarose gel chromatography when he was a teenager. He went on the develop analytical gel chromatography methods for determinations of many important characteristics of water-soluble proteins; diffusion coefficient, molecular size, [3][4] thermodynamics of protein-protein interactions including important changes due to single amino acid substitutions. [5]
Referencesedit
^"Obituary - Gary K. Ackers". Biophysical Society. August 2011. Retrieved 15 July 2013.
^Gary Ackers 2010-06-07 at the Wayback Machine faculty page at Washington University in St. Louis. Accessed on 2010-02-01.
^ Ackers GK (1967). "Molecular sieve studies of interacting protein systems. I. Equations for transport of associating systems". J. Biol. Chem.242 (13): 3026–3034. doi:10.1016/S0021-9258(18)95928-4. PMID 6027787.
^ Ackers GK (1969). "Molecular sieve studies of interacting protein systems. IV. Molecular size of the D-amino acid oxidase apoenzyme subunit". J. Biol. Chem.244 (2): 465–470. doi:10.1016/S0021-9258(18)94452-2. PMID 4388073.
^ Pettigrew DW, Romeo PH, Tsapis A, Thillet J, Smith ML, Turner BW, Ackers GK (1982). "Probing the energetics of proteins through structural perturbation: sites of regulatory energy in human hemoglobin". PNAS. 79 (6): 1849–1853. Bibcode:1982PNAS...79.1849P. doi:10.1073/pnas.79.6.1849. PMC346078. PMID 6952235.{{cite journal}}: CS1 maint: multiple names: authors list (link)
May 07, 2024
gary, ackers, gary, keith, ackers, 1939, 2011, emeritus, professor, biochemistry, molecular, biophysics, washington, university, louis, missouri, gary, keith, ackersborn1939died2011nationalityamericanknown, foragarose, chromatographyscientific, careerfieldsthe. Gary Keith Ackers 1939 2011 1 was Emeritus Professor of Biochemistry and Molecular Biophysics of Washington University in St Louis Missouri Gary Keith AckersBorn1939Died2011NationalityAmericanKnown forAgarose gel chromatographyScientific careerFieldsThermodynamic linkage analysis of biological macromolecules cooperative O2 binding to hemoglobinInstitutionsWashington University in St Louis His research focused on thermodynamic linkage analysis of biological macromolecules addressing the molecular mechanism of cooperative O2 binding to human hemoglobin since the early 1970s He was a Fellow of the Biophysical Society and one of the founders of the annual Gibbs Conference 2 Professor Ackers invented agarose gel chromatography when he was a teenager He went on the develop analytical gel chromatography methods for determinations of many important characteristics of water soluble proteins diffusion coefficient molecular size 3 4 thermodynamics of protein protein interactions including important changes due to single amino acid substitutions 5 References edit Obituary Gary K Ackers Biophysical Society August 2011 Retrieved 15 July 2013 Gary Ackers Archived 2010 06 07 at the Wayback Machine faculty page at Washington University in St Louis Accessed on 2010 02 01 Ackers GK 1967 Molecular sieve studies of interacting protein systems I Equations for transport of associating systems J Biol Chem 242 13 3026 3034 doi 10 1016 S0021 9258 18 95928 4 PMID 6027787 Ackers GK 1969 Molecular sieve studies of interacting protein systems IV Molecular size of the D amino acid oxidase apoenzyme subunit J Biol Chem 244 2 465 470 doi 10 1016 S0021 9258 18 94452 2 PMID 4388073 Pettigrew DW Romeo PH Tsapis A Thillet J Smith ML Turner BW Ackers GK 1982 Probing the energetics of proteins through structural perturbation sites of regulatory energy in human hemoglobin PNAS 79 6 1849 1853 Bibcode 1982PNAS 79 1849P doi 10 1073 pnas 79 6 1849 PMC 346078 PMID 6952235 a href Template Cite journal html title Template Cite journal cite journal a CS1 maint multiple names authors list link Retrieved from https en wikipedia org w index php title Gary Ackers amp oldid 1108068041, wikipedia, wiki, book, books, library,
