Foralumab is a fully human monoclonal antibody that binds to CD3 epsilon.[1] Also called TZLS-401, it is currently in clinical development by Tiziana Life Sciences for treatment of Crohn's disease and other autoimmune diseases.[2] However foralumab did not show efficacy for Crohn's disease.[3]
It is currently in clinical development by Tiziana Life Sciences for treatment of secondary progressive Multiple sclerosis.[4][5]
ReferencesEdit
^World Health Organization (2010). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 103" (PDF). WHO Drug Information.
foralumab, fully, human, monoclonal, antibody, that, binds, epsilon, also, called, tzls, currently, clinical, development, tiziana, life, sciences, treatment, crohn, disease, other, autoimmune, diseases, however, foralumab, show, efficacy, crohn, disease, mono. Foralumab is a fully human monoclonal antibody that binds to CD3 epsilon 1 Also called TZLS 401 it is currently in clinical development by Tiziana Life Sciences for treatment of Crohn s disease and other autoimmune diseases 2 However foralumab did not show efficacy for Crohn s disease 3 ForalumabMonoclonal antibodyTypeWhole antibodySourceHumanTargetCD3 epsilonClinical dataATC codenoneIdentifiersCAS Number946415 64 1 NChemSpidernoneUNIIJ43DL56H6M N Y what is this verify It is currently in clinical development by Tiziana Life Sciences for treatment of secondary progressive Multiple sclerosis 4 5 References Edit World Health Organization 2010 International Nonproprietary Names for Pharmaceutical Substances INN Proposed INN List 103 PDF WHO Drug Information Foralumab Tiziana Life Sciences plc Giuffrida P Di Sabatino A September 2020 Targeting T cells in inflammatory bowel disease Pharmacological Research 159 105040 doi 10 1016 j phrs 2020 105040 PMID 32585338 S2CID 220073839 Wexler M 2nd SPMS Patient Sees Clinical Gains With Foralumab Treatment Multiple Sclerosis News Today Retrieved 16 June 2022 Intranasal Foralumab Provides Neuroimaging and Clinical Improvements in Secondary Progressive Multiple Sclerosis practicalneurology Retrieved 6 August 2022 This monoclonal antibody related article is a stub You can help Wikipedia by expanding it vte This antineoplastic or immunomodulatory drug article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Foralumab amp oldid 1154680498, wikipedia, wiki, book, books, library,
