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Flusilazole

Flusilazole (DPX-H6573) is an organosilicon fungicide invented by DuPont, which is used to control fungal infections on a variety of fruit and vegetable crops.[1][2][3] It is moderately toxic to animals and has been shown to produce birth defects in high doses.[4][5]

Flusilazole
Names
Preferred IUPAC name
1-{[Bis(4-fluorophenyl)(methyl)silyl]methyl}-1H-1,2,4-triazole
Other names
DPX-H6573;
Identifiers
  • 85509-19-9 Y
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:81922 N
ChemSpider
  • 66326 N
ECHA InfoCard 100.107.525
  • 73675
UNII
  • F3WG2VVD87 Y
  • DTXSID3024235
  • InChI=1S/C16H15F2N3Si/c1-22(12-21-11-19-10-20-21,15-6-2-13(17)3-7-15)16-8-4-14(18)5-9-16/h2-11H,12H2,1H3 N
    Key: FQKUGOMFVDPBIZ-UHFFFAOYSA-N N
  • InChI=1/C16H15F2N3Si/c1-22(12-21-11-19-10-20-21,15-6-2-13(17)3-7-15)16-8-4-14(18)5-9-16/h2-11H,12H2,1H3
    Key: FQKUGOMFVDPBIZ-UHFFFAOYAI
  • c2ncnn2C[Si](C)(c(cc1)ccc1F)c3ccc(F)cc3
Properties
C16H15F2N3Si
Molar mass 315.392 g/mol
41.9 mg/L (20°C)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)

References edit

  1. ^ Moberg, W. K.; Basarab, G. S.; Cuomo, J.; Liang, P. H. (1987). "Biologically Active Organosilicon Compounds". Synthesis and Chemistry of Agrochemicals. ACS Symposium Series. Vol. 355. pp. 288–301. doi:10.1021/bk-1987-0355.ch026. ISBN 9780841214347.
  2. ^ Bostanian NJ, Larocque N, Chouinard G, Coderre D (November 2001). "Baseline toxicity of several pesticides to Hyaliodes vitripennis (Say) (Hemiptera: Miridae)". Pest Management Science. 57 (11): 1007–10. doi:10.1002/ps.374. PMID 11721516.
  3. ^ Eckert MR, Rossall S, Selley A, Fitt BD (April 2010). "Effects of fungicides on in vitro spore germination and mycelial growth of the phytopathogens Leptosphaeria maculans and L. biglobosa (phoma stem canker of oilseed rape)". Pest Management Science. 66 (4): 396–405. doi:10.1002/ps.1890. PMID 20013877.
  4. ^ Farag AT, Ibrahim HH (February 2007). "Developmental toxic effects of antifungal flusilazole administered by gavage to mice". Birth Defects Research Part B: Developmental and Reproductive Toxicology. 80 (1): 12–7. doi:10.1002/bdrb.20098. PMID 17187383.
  5. ^ Hermsen SA, van den Brandhof EJ, van der Ven LT, Piersma AH (January 2011). "Relative embryotoxicity of two classes of chemicals in a modified zebrafish embryotoxicity test and comparison with their in vivo potencies". Toxicology in Vitro. 25 (3): 745–753. doi:10.1016/j.tiv.2011.01.005. PMID 21238576.

External links edit

  • Flusilazole in the Pesticide Properties DataBase (PPDB)


flusilazole, h6573, organosilicon, fungicide, invented, dupont, which, used, control, fungal, infections, variety, fruit, vegetable, crops, moderately, toxic, animals, been, shown, produce, birth, defects, high, doses, names, preferred, iupac, name, fluorophen. Flusilazole DPX H6573 is an organosilicon fungicide invented by DuPont which is used to control fungal infections on a variety of fruit and vegetable crops 1 2 3 It is moderately toxic to animals and has been shown to produce birth defects in high doses 4 5 Flusilazole Names Preferred IUPAC name 1 Bis 4 fluorophenyl methyl silyl methyl 1H 1 2 4 triazole Other names DPX H6573 Identifiers CAS Number 85509 19 9 Y 3D model JSmol Interactive image ChEBI CHEBI 81922 N ChemSpider 66326 N ECHA InfoCard 100 107 525 PubChem CID 73675 UNII F3WG2VVD87 Y CompTox Dashboard EPA DTXSID3024235 InChI InChI 1S C16H15F2N3Si c1 22 12 21 11 19 10 20 21 15 6 2 13 17 3 7 15 16 8 4 14 18 5 9 16 h2 11H 12H2 1H3 NKey FQKUGOMFVDPBIZ UHFFFAOYSA N NInChI 1 C16H15F2N3Si c1 22 12 21 11 19 10 20 21 15 6 2 13 17 3 7 15 16 8 4 14 18 5 9 16 h2 11H 12H2 1H3Key FQKUGOMFVDPBIZ UHFFFAOYAI SMILES c2ncnn2C Si C c cc1 ccc1F c3ccc F cc3 Properties Chemical formula C16H15F2N3Si Molar mass 315 392 g mol Solubility in water 41 9 mg L 20 C Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa N verify what is Y N Infobox referencesReferences edit Moberg W K Basarab G S Cuomo J Liang P H 1987 Biologically Active Organosilicon Compounds Synthesis and Chemistry of Agrochemicals ACS Symposium Series Vol 355 pp 288 301 doi 10 1021 bk 1987 0355 ch026 ISBN 9780841214347 Bostanian NJ Larocque N Chouinard G Coderre D November 2001 Baseline toxicity of several pesticides to Hyaliodes vitripennis Say Hemiptera Miridae Pest Management Science 57 11 1007 10 doi 10 1002 ps 374 PMID 11721516 Eckert MR Rossall S Selley A Fitt BD April 2010 Effects of fungicides on in vitro spore germination and mycelial growth of the phytopathogens Leptosphaeria maculans and L biglobosa phoma stem canker of oilseed rape Pest Management Science 66 4 396 405 doi 10 1002 ps 1890 PMID 20013877 Farag AT Ibrahim HH February 2007 Developmental toxic effects of antifungal flusilazole administered by gavage to mice Birth Defects Research Part B Developmental and Reproductive Toxicology 80 1 12 7 doi 10 1002 bdrb 20098 PMID 17187383 Hermsen SA van den Brandhof EJ van der Ven LT Piersma AH January 2011 Relative embryotoxicity of two classes of chemicals in a modified zebrafish embryotoxicity test and comparison with their in vivo potencies Toxicology in Vitro 25 3 745 753 doi 10 1016 j tiv 2011 01 005 PMID 21238576 External links editFlusilazole in the Pesticide Properties DataBase PPDB nbsp This article about an organic compound is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Flusilazole amp oldid 1151028938, wikipedia, wiki, book, books, library,

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