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Wikipedia

FCMR

Fc fragment of IgM receptor is a protein that in humans is encoded by the FCMR gene. [5]

FCMR
Identifiers
AliasesFCMR, TOSO, FAIM3, Fc fragment of IgM receptor, Fc mu receptor, FcmuR
External IDsOMIM: 606015 MGI: 1916419 HomoloGene: 48347 GeneCards: FCMR
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001142472
NM_001142473
NM_001193338
NM_005449

NM_026976

RefSeq (protein)

NP_001135945
NP_001180267
NP_005440

NP_081252
NP_001392822

Location (UCSC)Chr 1: 206.9 – 206.92 MbChr 1: 130.79 – 130.81 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function edit

Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).

References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162894 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042474 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Fc fragment of IgM receptor". Retrieved 2016-03-24.

Further reading edit

  • Sigruener A, Buechler C, Bared SM, Grandl M, Aslanidis C, Ugocsai P, Gehrmann M, Schmitz G (2007). "E-LDL upregulates TOSO expression and enhances the survival of human macrophages". Biochem. Biophys. Res. Commun. 359 (3): 723–8. doi:10.1016/j.bbrc.2007.05.169. PMID 17553462.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


fcmr, fragment, receptor, protein, that, humans, encoded, gene, identifiersaliases, toso, faim3, fragment, receptor, receptor, fcmurexternal, idsomim, 606015, 1916419, homologene, 48347, genecards, gene, location, human, chromosome, human, band1q32, 1start206,. Fc fragment of IgM receptor is a protein that in humans is encoded by the FCMR gene 5 FCMRIdentifiersAliasesFCMR TOSO FAIM3 Fc fragment of IgM receptor Fc mu receptor FcmuRExternal IDsOMIM 606015 MGI 1916419 HomoloGene 48347 GeneCards FCMRGene location Human Chr Chromosome 1 human 1 Band1q32 1Start206 903 317 bp 1 End206 923 247 bp 1 Gene location Mouse Chr Chromosome 1 mouse 2 Band1 1 E4Start130 793 406 bp 2 End130 808 528 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inspleenlymph nodeappendixbloodbone marrow cellsthymusthymussuperficial temporal arterygallbladdergastrocnemius muscleTop expressed inspleenbloodsubcutaneous adipose tissuewhite adipose tissuesubmandibular glandbone marrowthymusright lung lobemammary glandseminiferous tubuleMore reference expression dataBioGPSn aOrthologsSpeciesHumanMouseEntrez921469169EnsemblENSG00000162894ENSMUSG00000042474UniProtO60667A1KXC4RefSeq mRNA NM 001142472NM 001142473NM 001193338NM 005449NM 026976RefSeq protein NP 001135945NP 001180267NP 005440NP 081252NP 001392822Location UCSC Chr 1 206 9 206 92 MbChr 1 130 79 130 81 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseFunction editFc receptors specifically bind to the Fc region of immunoglobulins Igs to mediate the unique functions of each Ig class FAIM3 encodes an Fc receptor for IgM see MIM 147020 Kubagawa et al 2009 PubMed 19858324 Shima et al 2010 PubMed 20042454 References edit a b c GRCh38 Ensembl release 89 ENSG00000162894 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000042474 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Entrez Gene Fc fragment of IgM receptor Retrieved 2016 03 24 Further reading editSigruener A Buechler C Bared SM Grandl M Aslanidis C Ugocsai P Gehrmann M Schmitz G 2007 E LDL upregulates TOSO expression and enhances the survival of human macrophages Biochem Biophys Res Commun 359 3 723 8 doi 10 1016 j bbrc 2007 05 169 PMID 17553462 This article incorporates text from the United States National Library of Medicine which is in the public domain nbsp This article on a gene on human chromosome 1 is a stub You can help Wikipedia by expanding it vte nbsp This protein related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title FCMR amp oldid 1081539010, wikipedia, wiki, book, books, library,

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