Chemokine (C-C motif) ligand 26 (CCL26) is a small cytokine belonging to the CC chemokine family that is also called Eotaxin-3, Macrophage inflammatory protein 4-alpha (MIP-4-alpha), Thymic stroma chemokine-1 (TSC-1), and IMAC. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokineinterleukin 4.[1][2] CCL26 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptorCCR3.[3] This gene for chemokine is located on human chromosome 7.[4]
^Shinkai et al. A novel human CC chemokine, eotaxin-3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinophils. J. Immunol. 163:1602-1610, 1999.
^Guo et al. Molecular cloning and characterization of a novel human CC chemokine, SCYA26. Genomics 58:313-317, 1999.
^Kitaura et al. Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3. J. Biol. Chem. 274:27975-27980, 1999.
^Hillier et al. The DNA sequence of human chromosome 7. Nature 424:157-164, 2003.
ccl26, chemokine, motif, ligand, small, cytokine, belonging, chemokine, family, that, also, called, eotaxin, macrophage, inflammatory, protein, alpha, alpha, thymic, stroma, chemokine, imac, expressed, several, tissues, including, heart, lung, ovary, endotheli. Chemokine C C motif ligand 26 CCL26 is a small cytokine belonging to the CC chemokine family that is also called Eotaxin 3 Macrophage inflammatory protein 4 alpha MIP 4 alpha Thymic stroma chemokine 1 TSC 1 and IMAC It is expressed by several tissues including heart lung and ovary and in endothelial cells that have been stimulated with the cytokine interleukin 4 1 2 CCL26 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3 3 This gene for chemokine is located on human chromosome 7 4 chemokine C C motif ligand 26IdentifiersSymbolCCL26Alt symbolsSCYA26 MIP 4alpha eotaxin 3 IMAC MIP 4a TSC 1NCBI gene10344HGNC10625OMIM604697PDB1G2TRefSeqNM 006072UniProtQ9Y258Other dataLocusChr 7 q11 2Search forStructuresSwiss modelDomainsInterProReferences edit Shinkai et al A novel human CC chemokine eotaxin 3 which is expressed in IL 4 stimulated vascular endothelial cells exhibits potent activity toward eosinophils J Immunol 163 1602 1610 1999 Guo et al Molecular cloning and characterization of a novel human CC chemokine SCYA26 Genomics 58 313 317 1999 Kitaura et al Molecular cloning of a novel human CC chemokine Eotaxin 3 that is a functional ligand of CC chemokine receptor 3 J Biol Chem 274 27975 27980 1999 Hillier et al The DNA sequence of human chromosome 7 Nature 424 157 164 2003 External links editCCL26 human gene location in the UCSC Genome Browser CCL26 human gene details in the UCSC Genome Browser nbsp This article on a gene on human chromosome 7 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title CCL26 amp oldid 1159542176, wikipedia, wiki, book, books, library,
