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Uganda Virus Research Institute

April 12, 2024

The Uganda Virus Research Institute (UVRI) is a medical research institute owned by the Uganda government that carries out research on communicable diseases in man and animals, with emphasis on viral transmitted infections. UVRI is a component of Uganda National Health Research Organization (UNHRO), an umbrella organization for health research within Uganda.[1]

Uganda Virus Research Institute
UVRI

The Uganda Virus Research Institute in 2018
Medical Research Institute overview
FormedJanuary 1, 1936; 88 years ago (1936-01-01)
TypeMedical Research Institute
JurisdictionGovernment of Uganda
Headquarters51-59 Nakiwogo Road, Entebbe, Uganda
Medical Research Institute executive
WebsiteHomepage
Video of the institute in 2018

Location edit

UVRI is located at 51-59 Nakiwogo Road, in Entebbe, Uganda, approximately 36 kilometres (22 mi), south of Kampala, the capital and largest city in Uganda.[2] The coordinates of the institute are: 0°04'33.0"N, 32°27'26.0"E (Latitude:0.075833; Longitude:32.457222).[3]

Overview edit

The organisation was established in 1936 as the Yellow Fever Research Institute by the Rockefeller Foundation. In 1947, scientists researching yellow fever placed a rhesus macaque in a cage in the Zika Forest. The monkey developed a fever, and researchers isolated from its serum a transmissible agent that was first described as Zika virus in 1952.[4] Other noteworthy arboviruses discovered at the institute include Chikungunya virus, West Nile virus, Bwamba virus, Semliki Forest virus, O'nyong'nyong virus, and Kadam virus.[5][6]

In 1950, after gaining regional recognition, the institute was renamed the East African Virus Research Institute, under which identity many of its noteworthy accomplishments were published. In 1977, it was reorganized under its current name.[5]

Organization edit

After the collapse of the East African Community in 1977, it became a Ugandan government public health research institution and was renamed the Uganda Virus Research Institute. The government of Uganda administers and funds the UVRI through the Uganda National Health Research Organization, which is an umbrella research body within the Uganda Ministry of Health.[1]

The mission of UVRI is to carry out scientific research concerning communicable diseases, especially viral diseases of public health importance, and to advise the government on strategies for control and prevention.[1]

UVRI also plays a large role in coordinating and administering virology related clinical trials within the country. Most recently, UVRI has been involved in human HIV vaccine clinical trials. The HIV/AIDS Reference and Quality Assurance Laboratory, which is part of UVRI, plays an important role in making public policy recommendations to the National Food and Drug Authority on the access and usage of new drugs and medical technologies.[1] UVRI maintains a field station at the Zika Forest near Entebbe.[7]

Administration edit

The institute is divided into the following departments and units.

Departments

(1) The Office of the Director (Head of Programs and Partnerships). The director is responsible for providing leadership to the research community. He/She reports directly to the UVRI Advisory Board (UAB).[8] (2) The Office of the Deputy Director (Chief Research Officer (CRO). The CRO is responsible for coordinating all the research being undertaken by the scientific departments in the institute. The CRO deputizes the director as the need arises.[8] (3) Department of Finance and Administration. This department is responsible for administration, accounting, payroll, transport, security, human resources management, logistics, legal affairs, storage and community awareness programs.[9]

(4) Department of Ecology and Zoology. This department carries out research on the animals and insects that carry pathogens which cause diseases in humans. These include monkeys, rodents, ticks, bats, and others.[10] (5) Department of General Virology.he Department of General Virology is headed by an assistant director. It conducts comprehensive research at a molecular and cellular level for different viral-borne diseases. This is the department that conducts research related to viruses associated with human cancers, including HHV8, HPV16, HPV18, Epstein–Barr virus and others.[11] (6) Department of Entomology and Vector Biology. The department focuses on the study of insect vectors in the transmission of arbo-virus infections, and the study of other arthropods connected with other diseases of public health importance such as the vectors of malaria.[12]

(7) Department of Immunology. This department focuses on the comprehensive study of how the human body protects itself against infection. The department specializes into two areas, (a) the study of cellular and humoral immunity and (b) the practice of diagnosis and surveillance of viral and vector-borne diseases.[13] (8) Department of Arbovirology (Emerging and Re-Emerging). This department serves as a national and international reference centre in the field and laboratory research and epidemic aid investigations of vector-borne viral infections and their arthropod vectors.[14] (9) Department of Planning and Fund Raising. This department is responsible for drawing up annual and five-year institutional funding plans and programs. It also coordinates national funding with donor funding from international collaborators and donor agencies. The department also carries out active lobbying and fundraising, both nationally and internationally. Human resource planning and forecasting, budgetting, report-writing and dissemination, are some of the activities that occur here.[15]

Specialized units

The specialized units include the following:[16]

(1) Epidemiology Unit, responsible for investigation of epidemic outbreaks, particularity in the areas of HIV/AIDS, sexually transmitted diseases, malaria and acute viral outbreaks. The unit provides statistical an epidemiology support to the entire institute. (2) Immunisable Diseases Unit, carries out surveillance and research on diseases that are preventable with vaccines. Functions as a regional measles reference laboratory for the World Health Organization. (3) Clinical Research Unit, conducts applied research on viral infectious diseases. The unit also offers basic clinical services to staff and the immediate family members in a healthcare centre, supervised by Entebbe General Hospital. (4) Quality Assurance Unit, is responsible for setting standards, monitoring, evaluation of clinical and operational research. It is mandated to develop and review quality assurance and inspection procedures. (5) Internal Audit Unit, because of its constitutional mandate and direct linkage with the Auditor general's office, this unit reports directly to the director of UVRI. (6) Information Technology & Corporate Affairs Unit, is responsible for collecting, collating and dissemination of information in a manner that promotes ethics, specificity, professionalism, and timeliness to promote effective beneficial use of that information. (7) International Relations & Training Unit, is responsible for training and capacity building among UVRI staff, particularly the scientists. The unit arranges and coordinates national, regional and international participation of UVRI in all health research-related matters. Interacts with governments, development partners, NGOs and international philanthropic bodies on scientific and technical matters related to health and scientific funding, training and disease control.[citation needed]

See also edit

References edit

  1. ^ a b c d Vision Staff (17 February 2016). "The Uganda Virus Research Institute (UVRI)". New Vision. Kampala. Retrieved 24 October 2016.
  2. ^ Globefeed.com (24 October 2016). "Distance between Post Bus Uganda Limited Terminal, Kampala Road, Kampala, Central Region, Uganda and Uganda Virus Research Institute, Nakiwogo Road, Entebbe, Uganda". Globefeed.com. Retrieved 24 October 2016.
  3. ^ Google (24 October 2016). "Location of Uganda Virus Research Institute, Entebbe, Uganda" (Map). Google Maps. Google. Retrieved 24 October 2016.
  4. ^ Dick, G.W.A; Kitchen, S.F; Haddow, A.J (September 1952). "Zika Virus (I). Isolations and serological specificity". Transactions of the Royal Society of Tropical Medicine and Hygiene. 46 (5): 509–520. doi:10.1016/0035-9203(52)90042-4. PMID 12995440.
  5. ^ a b East African Virus Research Institute (27 August 2014). "History of Health Research at UVRI". Entebbe. Retrieved 24 October 2016.
  6. ^ Remi N. Charrel; Xavier de Lamballerie; Ali Mohamed Zaki (2008). "Human Cases of Hemorrhagic Fever in Saudi Arabia Due to a Newly Discovered Flavivirus, Alkhurma Hemorrhagic Fever Virus". In Yichen Lu; M. Essex; Bryan Roberts (eds.). Emerging Infections in Asia. pp. 179–192. doi:10.1007/978-0-387-75722-3_11. ISBN 978-0-387-75721-6.
  7. ^ Kaddumukasa, M. A.; Mutebi, J.-P.; Lutwama, J. J.; Masembe, C.; Akol, A. M. (1 January 2014). "Mosquitoes of Zika Forest, Uganda: Species Composition and Relative Abundance". Journal of Medical Entomology. 51 (1): 104–113. doi:10.1603/ME12269. PMC 6555620. PMID 24605459.
  8. ^ a b UVRI (24 October 2016). "The Office of the Director (Head of Programs and Partnerships)". Entebbe: Uganda Virus Research Institute (UVRI). Retrieved 24 October 2016.
  9. ^ UVRI (24 October 2016). "Uganda Virus Research Institute: Department of Finance and Administration". Entebbe: Uganda Virus Research Institute (UVRI). Retrieved 24 October 2016.
  10. ^ UVRI (24 October 2016). "Uganda Virus Research Institute: Department of Ecology and Zoology". Entebbe: Uganda Virus Research Institute (UVRI). Retrieved 24 October 2016.
  11. ^ UVRI (24 October 2016). "Uganda Virus Research Institute: Department of General Virology". Entebbe: Uganda Virus Research Institute (UVRI). Retrieved 24 October 2016.
  12. ^ UVRI (24 October 2016). "Uganda Virus Research Institute: Department of Entomology and Vector Biology". Entebbe: Uganda Virus Research Institute (UVRI). Retrieved 24 October 2016.
  13. ^ UVRI (24 October 2016). "Uganda Virus Research Institute: Department of Immunology". Entebbe: Uganda Virus Research Institute (UVRI). Retrieved 24 October 2016.
  14. ^ UVRI (24 October 2016). "Uganda Virus Research Institute: Department of Arboviroloy". Entebbe: Uganda Virus Research Institute (UVRI). Retrieved 24 October 2016.
  15. ^ UVRI (24 October 2016). "Uganda Virus Research Institute: Department of Planning and Fund Raising". Entebbe: Uganda Virus Research Institute (UVRI). Retrieved 24 October 2016.
  16. ^ UVRI (24 October 2016). "Uganda Virus Research Institute: Specialized Units and Divisions". Entebbe: Uganda Virus Research Institute (UVRI). Retrieved 24 October 2016.

Further reading edit

  • Sempala, S. D. K. (3 July 2002). "Institute Profile: The Uganda Virus Research Institute". Trends in Microbiology. 10 (7): 346–348. doi:10.1016/s0966-842x(02)02384-3. PMID 12110215.

External links edit

 
Wikimedia Commons has media related to Uganda Virus Research Institute.
  • Official website
  • Uganda Ministry of Health: UVRI
  • Programme Collaborators, DFID Knowledge Programme on HIV/AIDS and STI.

00°04′33″N 32°27′26″E / 0.07583°N 32.45722°E / 0.07583; 32.45722

April 12, 2024
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The Uganda Virus Research Institute UVRI is a medical research institute owned by the Uganda government that carries out research on communicable diseases in man and animals with emphasis on viral transmitted infections UVRI is a component of Uganda National Health Research Organization UNHRO an umbrella organization for health research within Uganda 1 Uganda Virus Research InstituteUVRIThe Uganda Virus Research Institute in 2018Medical Research Institute overviewFormedJanuary 1 1936 88 years ago 1936 01 01 TypeMedical Research InstituteJurisdictionGovernment of UgandaHeadquarters51 59 Nakiwogo Road Entebbe UgandaMedical Research Institute executiveProfessor Pontiano Kaleebu DirectorWebsiteHomepage source source source source source source source source Video of the institute in 2018 Contents 1 Location 2 Overview 3 Organization 4 Administration 5 See also 6 References 7 Further reading 8 External linksLocation editUVRI is located at 51 59 Nakiwogo Road in Entebbe Uganda approximately 36 kilometres 22 mi south of Kampala the capital and largest city in Uganda 2 The coordinates of the institute are 0 04 33 0 N 32 27 26 0 E Latitude 0 075833 Longitude 32 457222 3 Overview editThe organisation was established in 1936 as the Yellow Fever Research Institute by the Rockefeller Foundation In 1947 scientists researching yellow fever placed a rhesus macaque in a cage in the Zika Forest The monkey developed a fever and researchers isolated from its serum a transmissible agent that was first described as Zika virus in 1952 4 Other noteworthy arboviruses discovered at the institute include Chikungunya virus West Nile virus Bwamba virus Semliki Forest virus O nyong nyong virus and Kadam virus 5 6 In 1950 after gaining regional recognition the institute was renamed the East African Virus Research Institute under which identity many of its noteworthy accomplishments were published In 1977 it was reorganized under its current name 5 Organization editAfter the collapse of the East African Community in 1977 it became a Ugandan government public health research institution and was renamed the Uganda Virus Research Institute The government of Uganda administers and funds the UVRI through the Uganda National Health Research Organization which is an umbrella research body within the Uganda Ministry of Health 1 The mission of UVRI is to carry out scientific research concerning communicable diseases especially viral diseases of public health importance and to advise the government on strategies for control and prevention 1 UVRI also plays a large role in coordinating and administering virology related clinical trials within the country Most recently UVRI has been involved in human HIV vaccine clinical trials The HIV AIDS Reference and Quality Assurance Laboratory which is part of UVRI plays an important role in making public policy recommendations to the National Food and Drug Authority on the access and usage of new drugs and medical technologies 1 UVRI maintains a field station at the Zika Forest near Entebbe 7 Administration editThe institute is divided into the following departments and units Departments 1 The Office of the Director Head of Programs and Partnerships The director is responsible for providing leadership to the research community He She reports directly to the UVRI Advisory Board UAB 8 2 The Office of the Deputy Director Chief Research Officer CRO The CRO is responsible for coordinating all the research being undertaken by the scientific departments in the institute The CRO deputizes the director as the need arises 8 3 Department of Finance and Administration This department is responsible for administration accounting payroll transport security human resources management logistics legal affairs storage and community awareness programs 9 4 Department of Ecology and Zoology This department carries out research on the animals and insects that carry pathogens which cause diseases in humans These include monkeys rodents ticks bats and others 10 5 Department of General Virology he Department of General Virology is headed by an assistant director It conducts comprehensive research at a molecular and cellular level for different viral borne diseases This is the department that conducts research related to viruses associated with human cancers including HHV8 HPV16 HPV18 Epstein Barr virus and others 11 6 Department of Entomology and Vector Biology The department focuses on the study of insect vectors in the transmission of arbo virus infections and the study of other arthropods connected with other diseases of public health importance such as the vectors of malaria 12 7 Department of Immunology This department focuses on the comprehensive study of how the human body protects itself against infection The department specializes into two areas a the study of cellular and humoral immunity and b the practice of diagnosis and surveillance of viral and vector borne diseases 13 8 Department of Arbovirology Emerging and Re Emerging This department serves as a national and international reference centre in the field and laboratory research and epidemic aid investigations of vector borne viral infections and their arthropod vectors 14 9 Department of Planning and Fund Raising This department is responsible for drawing up annual and five year institutional funding plans and programs It also coordinates national funding with donor funding from international collaborators and donor agencies The department also carries out active lobbying and fundraising both nationally and internationally Human resource planning and forecasting budgetting report writing and dissemination are some of the activities that occur here 15 Specialized unitsThe specialized units include the following 16 1 Epidemiology Unit responsible for investigation of epidemic outbreaks particularity in the areas of HIV AIDS sexually transmitted diseases malaria and acute viral outbreaks The unit provides statistical an epidemiology support to the entire institute 2 Immunisable Diseases Unit carries out surveillance and research on diseases that are preventable with vaccines Functions as a regional measles reference laboratory for the World Health Organization 3 Clinical Research Unit conducts applied research on viral infectious diseases The unit also offers basic clinical services to staff and the immediate family members in a healthcare centre supervised by Entebbe General Hospital 4 Quality Assurance Unit is responsible for setting standards monitoring evaluation of clinical and operational research It is mandated to develop and review quality assurance and inspection procedures 5 Internal Audit Unit because of its constitutional mandate and direct linkage with the Auditor general s office this unit reports directly to the director of UVRI 6 Information Technology amp Corporate Affairs Unit is responsible for collecting collating and dissemination of information in a manner that promotes ethics specificity professionalism and timeliness to promote effective beneficial use of that information 7 International Relations amp Training Unit is responsible for training and capacity building among UVRI staff particularly the scientists The unit arranges and coordinates national regional and international participation of UVRI in all health research related matters Interacts with governments development partners NGOs and international philanthropic bodies on scientific and technical matters related to health and scientific funding training and disease control citation needed See also editUganda Cancer InstituteReferences edit a b c d Vision Staff 17 February 2016 The Uganda Virus Research Institute UVRI New Vision Kampala Retrieved 24 October 2016 Globefeed com 24 October 2016 Distance between Post Bus Uganda Limited Terminal Kampala Road Kampala Central Region Uganda and Uganda Virus Research Institute Nakiwogo Road Entebbe Uganda Globefeed com Retrieved 24 October 2016 Google 24 October 2016 Location of Uganda Virus Research Institute Entebbe Uganda Map Google Maps Google Retrieved 24 October 2016 Dick G W A Kitchen S F Haddow A J September 1952 Zika Virus I Isolations and serological specificity Transactions of the Royal Society of Tropical Medicine and Hygiene 46 5 509 520 doi 10 1016 0035 9203 52 90042 4 PMID 12995440 a b East African Virus Research Institute 27 August 2014 History of Health Research at UVRI Entebbe Retrieved 24 October 2016 Remi N Charrel Xavier de Lamballerie Ali Mohamed Zaki 2008 Human Cases of Hemorrhagic Fever in Saudi Arabia Due to a Newly Discovered Flavivirus Alkhurma Hemorrhagic Fever Virus In Yichen Lu M Essex Bryan Roberts eds Emerging Infections in Asia pp 179 192 doi 10 1007 978 0 387 75722 3 11 ISBN 978 0 387 75721 6 Kaddumukasa M A Mutebi J P Lutwama J J Masembe C Akol A M 1 January 2014 Mosquitoes of Zika Forest Uganda Species Composition and Relative Abundance Journal of Medical Entomology 51 1 104 113 doi 10 1603 ME12269 PMC 6555620 PMID 24605459 a b UVRI 24 October 2016 The Office of the Director Head of Programs and Partnerships Entebbe Uganda Virus Research Institute UVRI Retrieved 24 October 2016 UVRI 24 October 2016 Uganda Virus Research Institute Department of Finance and Administration Entebbe Uganda Virus Research Institute UVRI Retrieved 24 October 2016 UVRI 24 October 2016 Uganda Virus Research Institute Department of Ecology and Zoology Entebbe Uganda Virus Research Institute UVRI Retrieved 24 October 2016 UVRI 24 October 2016 Uganda Virus Research Institute Department of General Virology Entebbe Uganda Virus Research Institute UVRI Retrieved 24 October 2016 UVRI 24 October 2016 Uganda Virus Research Institute Department of Entomology and Vector Biology Entebbe Uganda Virus Research Institute UVRI Retrieved 24 October 2016 UVRI 24 October 2016 Uganda Virus Research Institute Department of Immunology Entebbe Uganda Virus Research Institute UVRI Retrieved 24 October 2016 UVRI 24 October 2016 Uganda Virus Research Institute Department of Arboviroloy Entebbe Uganda Virus Research Institute UVRI Retrieved 24 October 2016 UVRI 24 October 2016 Uganda Virus Research Institute Department of Planning and Fund Raising Entebbe Uganda Virus Research Institute UVRI Retrieved 24 October 2016 UVRI 24 October 2016 Uganda Virus Research Institute Specialized Units and Divisions Entebbe Uganda Virus Research Institute UVRI Retrieved 24 October 2016 Further reading editSempala S D K 3 July 2002 Institute Profile The Uganda Virus Research Institute Trends in Microbiology 10 7 346 348 doi 10 1016 s0966 842x 02 02384 3 PMID 12110215 External links edit nbsp Wikimedia Commons has media related to Uganda Virus Research Institute Official website Uganda Ministry of Health UVRI Programme Collaborators DFID Knowledge Programme on HIV AIDS and STI 00 04 33 N 32 27 26 E 0 07583 N 32 45722 E 0 07583 32 45722 Retrieved from https en wikipedia org w index php title Uganda Virus Research Institute amp oldid 1172381062, wikipedia, wiki, book, books, library,

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