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Derivative (chemistry)

In chemistry, a derivative is a compound that is derived from a similar compound by a chemical reaction.

In the past, derivative also meant a compound that can be imagined to arise from another compound, if one atom or group of atoms is replaced with another atom or group of atoms,[1] but modern chemical language now uses the term structural analog for this meaning, thus eliminating ambiguity.[citation needed] The term "structural analogue" is common in organic chemistry.

In biochemistry, the word is used for compounds that at least theoretically can be formed from the precursor compound.[2]

Chemical derivatives may be used to facilitate analysis. For example, melting point (MP) analysis can assist in identification of many organic compounds. A crystalline derivative may be prepared, such as a semicarbazone or 2,4-dinitrophenylhydrazone (derived from aldehydes or ketones), as a simple way of verifying the identity of the original compound, assuming that a table of derivative MP values is available.[3] Prior to the advent of spectroscopic analysis, such methods were widely used.

In analytical chemistry, derivatization can be used to convert analytes into other species for improving detection. For example, polar groups such as N-H or O-H can be converted into less polar groups. This reaction reduces the boiling point of the molecule, allowing non-volatile compounds to be analyzed by gas chromatography.[4]

See also edit

References edit

  1. ^ "Definition of Derivative". Chemicool. 2007-09-18. from the original on 2021-08-31. Retrieved 2007-09-18.
  2. ^ Oxford Dictionary of Biochemistry and Molecular Biology. Oxford University Press. 2003. ISBN 0-19-850673-2.
  3. ^ Williamson, Kenneth L. (1999). Macroscale and Microscale Organic Experiments, 3rd ed. Boston: Houghton-Mifflin. pp. 426–7. ISBN 0-395-90220-7.
  4. ^ Jones, Jay; Stenerson, Katherine. "The Use of Derivatization Reagents for GC". SIgma Aldrich. from the original on 2023-02-09. Retrieved 2023-05-10.


derivative, chemistry, chemistry, derivative, compound, that, derived, from, similar, compound, chemical, reaction, past, derivative, also, meant, compound, that, imagined, arise, from, another, compound, atom, group, atoms, replaced, with, another, atom, grou. In chemistry a derivative is a compound that is derived from a similar compound by a chemical reaction In the past derivative also meant a compound that can be imagined to arise from another compound if one atom or group of atoms is replaced with another atom or group of atoms 1 but modern chemical language now uses the term structural analog for this meaning thus eliminating ambiguity citation needed The term structural analogue is common in organic chemistry In biochemistry the word is used for compounds that at least theoretically can be formed from the precursor compound 2 Chemical derivatives may be used to facilitate analysis For example melting point MP analysis can assist in identification of many organic compounds A crystalline derivative may be prepared such as a semicarbazone or 2 4 dinitrophenylhydrazone derived from aldehydes or ketones as a simple way of verifying the identity of the original compound assuming that a table of derivative MP values is available 3 Prior to the advent of spectroscopic analysis such methods were widely used In analytical chemistry derivatization can be used to convert analytes into other species for improving detection For example polar groups such as N H or O H can be converted into less polar groups This reaction reduces the boiling point of the molecule allowing non volatile compounds to be analyzed by gas chromatography 4 See also editDerivatization Precursor chemistry Product chemistry Structural analogReferences edit Definition of Derivative Chemicool 2007 09 18 Archived from the original on 2021 08 31 Retrieved 2007 09 18 Oxford Dictionary of Biochemistry and Molecular Biology Oxford University Press 2003 ISBN 0 19 850673 2 Williamson Kenneth L 1999 Macroscale and Microscale Organic Experiments 3rd ed Boston Houghton Mifflin pp 426 7 ISBN 0 395 90220 7 Jones Jay Stenerson Katherine The Use of Derivatization Reagents for GC SIgma Aldrich Archived from the original on 2023 02 09 Retrieved 2023 05 10 nbsp This article about chemical compounds is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Derivative chemistry amp oldid 1165870359, wikipedia, wiki, book, books, library,

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