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Cytidine triphosphate

February 15, 2024

Cytidine triphosphate (CTP) is a pyrimidine nucleoside triphosphate. CTP, much like ATP, consists of a ribose sugar, and three phosphate groups. The major difference between the two molecules is the base used, which in CTP is cytosine.

Cytidine triphosphate
Names
IUPAC name
Cytidine 5′-(tetrahydrogen triphosphate)
Systematic IUPAC name
O1-{[(2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl} tetrahydrogen triphosphate
Other names
CTP; Cytidine-5'-triphosphate
Identifiers
  • 65-47-4 Y
3D model (JSmol)
  • Interactive image
  • Interactive image
ChemSpider
  • 19952488 Y
ECHA InfoCard 100.000.556
  • 1741
MeSH Cytidine+triphosphate
  • 6176
UNII
  • K0118UX80T Y
  • DTXSID70889324
  • InChI=1S/C9H13N3O5.3H3O4P/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;3*1-5(2,3)4/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);3*(H3,1,2,3,4)/t4-,6-,7-,8-;;;/m1.../s1 Y
    Key: NPIWPFUCEAMYFN-LLWADOMFSA-N Y
  • InChI=1/C9H16N3O14P3/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
    Key: PCDQPRRSZKQHHS-XVFCMESIBL
  • InChI=1/C9H13N3O5.3H3O4P/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;3*1-5(2,3)4/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);3*(H3,1,2,3,4)/t4-,6-,7-,8-;;;/m1.../s1
    Key: NPIWPFUCEAMYFN-LLWADOMFBY
  • c1cn(c(=O)nc1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O
  • OP(O)(=O)O.OP(O)(=O)O.OP(O)(=O)O.N/C1=N/C(=O)N(/C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O
Properties
C9H16N3O14P3
Molar mass 483.156
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Y verify (what is YN ?)

CTP is a substrate in the synthesis of RNA.

CTP is a high-energy molecule similar to ATP, but its role as an energy coupler is limited to a much smaller subset of metabolic reactions. CTP is a coenzyme in metabolic reactions like the synthesis of glycerophospholipids, where it is used for activation and transfer of diacylglycerol and lipid head groups,[1] and glycosylation of proteins.

CTP acts as an inhibitor of the enzyme aspartate carbamoyltransferase, which is used in pyrimidine biosynthesis.[2]

See also edit

References edit

  1. ^ Buchanan BB, Gruissem W, Jones RL (2000). Biochemistry & molecular biology of plants (1st ed.). American society of plant physiology. ISBN 978-0-943088-39-6.
  2. ^ Blackburn, G. Michael. Nucleic Acids in Chemistry and Biology. The Royal Society of Chemistry, 2006, p. 119-120.

February 15, 2024
cytidine, triphosphate, pyrimidine, nucleoside, triphosphate, much, like, consists, ribose, sugar, three, phosphate, groups, major, difference, between, molecules, base, used, which, cytosine, namesiupac, name, cytidine, tetrahydrogen, triphosphate, systematic. Cytidine triphosphate CTP is a pyrimidine nucleoside triphosphate CTP much like ATP consists of a ribose sugar and three phosphate groups The major difference between the two molecules is the base used which in CTP is cytosine Cytidine triphosphate NamesIUPAC name Cytidine 5 tetrahydrogen triphosphate Systematic IUPAC name O1 2R 3S 4R 5R 5 4 Amino 2 oxopyrimidin 1 2H yl 3 4 dihydroxyoxolan 2 yl methyl tetrahydrogen triphosphateOther names CTP Cytidine 5 triphosphateIdentifiersCAS Number 65 47 4 Y3D model JSmol Interactive imageInteractive imageChemSpider 19952488 YECHA InfoCard 100 000 556IUPHAR BPS 1741MeSH Cytidine triphosphatePubChem CID 6176UNII K0118UX80T YCompTox Dashboard EPA DTXSID70889324InChI InChI 1S C9H13N3O5 3H3O4P c10 5 1 2 12 9 16 11 5 8 7 15 6 14 4 3 13 17 8 3 1 5 2 3 4 h1 2 4 6 8 13 15H 3H2 H2 10 11 16 3 H3 1 2 3 4 t4 6 7 8 m1 s1 YKey NPIWPFUCEAMYFN LLWADOMFSA N YInChI 1 C9H16N3O14P3 c10 5 1 2 12 9 15 11 5 8 7 14 6 13 4 24 8 3 23 28 19 20 26 29 21 22 25 27 16 17 18 h1 2 4 6 8 13 14H 3H2 H 19 20 H 21 22 H2 10 11 15 H2 16 17 18 t4 6 7 8 m1 s1Key PCDQPRRSZKQHHS XVFCMESIBLInChI 1 C9H13N3O5 3H3O4P c10 5 1 2 12 9 16 11 5 8 7 15 6 14 4 3 13 17 8 3 1 5 2 3 4 h1 2 4 6 8 13 15H 3H2 H2 10 11 16 3 H3 1 2 3 4 t4 6 7 8 m1 s1Key NPIWPFUCEAMYFN LLWADOMFBYSMILES c1cn c O nc1N C H 2 C H C H C H O2 CO P O O O P O O OP O O O O OOP O O O OP O O O OP O O O N C1 N C O N C C1 C H 2O C H CO C H O C H 2OPropertiesChemical formula C9H16N3O14P3Molar mass 483 156Except where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Y verify what is Y N Infobox references CTP is a substrate in the synthesis of RNA CTP is a high energy molecule similar to ATP but its role as an energy coupler is limited to a much smaller subset of metabolic reactions CTP is a coenzyme in metabolic reactions like the synthesis of glycerophospholipids where it is used for activation and transfer of diacylglycerol and lipid head groups 1 and glycosylation of proteins CTP acts as an inhibitor of the enzyme aspartate carbamoyltransferase which is used in pyrimidine biosynthesis 2 See also editCTP synthase Cytidine Cytosine Pyrimidine biosynthesisReferences edit Buchanan BB Gruissem W Jones RL 2000 Biochemistry amp molecular biology of plants 1st ed American society of plant physiology ISBN 978 0 943088 39 6 Blackburn G Michael Nucleic Acids in Chemistry and Biology The Royal Society of Chemistry 2006 p 119 120 Retrieved from https en wikipedia org w index php title Cytidine triphosphate amp oldid 1152505747, wikipedia, wiki, book, books, library,

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