Thiazide diuretics increase the excretion of sodium and potassium ions and decrease the excretion of calcium ions and uric acid so they are contraindicated in patients with hyponatraemia, hypokalaemia, hypercalcaemia and hyperuricaemia. They are also contraindicated in patients with Addison's disease.
cyclopenthiazide, trade, name, navidrex, thiazide, diuretic, used, treatment, heart, failure, hypertension, clinical, dataahfs, drugs, cominternational, drug, namesatc, codec03aa07, legal, statuslegal, statusuk, prescription, only, identifiersiupac, name, chlo. Cyclopenthiazide trade name Navidrex is a thiazide diuretic used in the treatment of heart failure and hypertension CyclopenthiazideClinical dataAHFS Drugs comInternational Drug NamesATC codeC03AA07 WHO Legal statusLegal statusUK POM Prescription only IdentifiersIUPAC name 6 chloro 3 cyclopentylmethyl 1 1 dioxo 3 4 dihydro 2H benzo e 1 2 4 thiadiazine 7 sulfonamideCAS Number742 20 1PubChem CID2904IUPHAR BPS7899ChemSpider2801UNIIVX4S2N85F5KEGGD02061 YChEMBLChEMBL1373254CompTox Dashboard EPA DTXSID4022868ECHA InfoCard100 010 920Chemical and physical dataFormulaC 13H 18Cl N 3O 4S 2Molar mass379 87 g mol 13D model JSmol Interactive imageSMILES O S O c1c Cl cc2c c1 S O O NC N2 CC3CCCC3 NInChI InChI 1S C13H18ClN3O4S2 c14 9 6 10 12 7 11 9 22 15 18 19 23 20 21 17 13 16 10 5 8 3 1 2 4 8 h6 8 13 16 17H 1 5H2 H2 15 18 19 Key BKYKPTRYDKTTJY UHFFFAOYSA N verify Contents 1 Synthesis 2 Contraindications 3 See also 4 ReferencesSynthesis edit nbsp Cyclopenthiazide synthesis 1 Contraindications editThiazide diuretics increase the excretion of sodium and potassium ions and decrease the excretion of calcium ions and uric acid so they are contraindicated in patients with hyponatraemia hypokalaemia hypercalcaemia and hyperuricaemia They are also contraindicated in patients with Addison s disease See also editCyclothiazide Hydrochlorothiazide BendroflumethiazideReferences edit Whitehead CW Traverso JJ Sullivan HR Marshall FJ 1961 Diuretics V 3 4 Dihydro 1 2 4 benzothiadiazine 1 1 Dioxides The Journal of Organic Chemistry 26 8 2814 2818 doi 10 1021 jo01066a046 nbsp This drug article relating to the cardiovascular system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Cyclopenthiazide amp oldid 1148499599, wikipedia, wiki, book, books, library,