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Wikipedia

Crotonylfentanyl

Crotonylfentanyl is an opioid analgesic that is an analog of fentanyl and structural isomer of cyclopropylfentanyl[1] and has been sold online as a designer drug.[2][3] In December 2019, the UNODC announced scheduling recommendations placing crotonylfentanyl into Schedule I.[4]

Crotonylfentanyl
Legal status
Legal status
Identifiers
  • (2E)-N-Phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-2-butenamide
CAS Number
  • 760930-59-4 Y
PubChem CID
  • 10472960
ChemSpider
  • 8648371
UNII
  • R0XLG8CO63
Chemical and physical data
FormulaC23H28N2O
Molar mass348.490 g·mol−1
3D model (JSmol)
  • Interactive image
  • O=C(/C=C/C)N(c1ccccc1)C3CCN(CCc2ccccc2)CC3
  • InChI=1S/C23H28N2O/c1-2-9-23(26)25(21-12-7-4-8-13-21)22-15-18-24(19-16-22)17-14-20-10-5-3-6-11-20/h2-13,22H,14-19H2,1H3/b9-2+
  • Key:VDYXGPCGBKLRDA-XNWCZRBMSA-N

  • InChI=1/C23H28N2O/c1-2-9-23(26)25(21-12-7-4-8-13-21)22-15-18-24(19-16-22)17-14-20-10-5-3-6-11-20/h2-13,22H,14-19H2,1H3/b9-2+
  • Key:VDYXGPCGBKLRDA-XNWCZRBMBF

See also

References

  1. ^ Mallette, Jennifer R.; Casale, John F.; Hays, Patrick A. (January 2019). "Characterization and differentiation of cyclopropylfentanyl from E-crotonylfentanyl, Z-crotonylfentanyl, and 3-butenylfentanyl". Science & Justice. 59 (1): 67–74. doi:10.1016/j.scijus.2018.07.005. ISSN 1355-0306. PMID 30654970. S2CID 58646707.
  2. ^ Varshneya, Neil B.; Walentiny, D. Matthew; Moisa, Lea T.; Walker, Teneille D.; Akinfiresoye, Luli R.; Beardsley, Patrick M. (June 2019). "Opioid-like antinociceptive and locomotor effects of emerging fentanyl-related substances". Neuropharmacology. 151: 171–179. doi:10.1016/j.neuropharm.2019.03.023. ISSN 0028-3908. PMC 8992608. PMID 30904478. S2CID 84182661.
  3. ^ Palaty J, Konforte D, Karakosta T, Wong E, Stefan C (March 2018). "Rapid identification of cyclopropyl fentanyl/crotonyl fentanyl in clinical urine specimens: A case study of clinical laboratory collaboration in Canada". Clinical Biochemistry. 53: 164–167. doi:10.1016/j.clinbiochem.2018.01.013. PMID 29395089.
  4. ^ "December 2019 – WHO: World Health Organization recommends 12 NPS for scheduling".

crotonylfentanyl, opioid, analgesic, that, analog, fentanyl, structural, isomer, cyclopropylfentanyl, been, sold, online, designer, drug, december, 2019, unodc, announced, scheduling, recommendations, placing, crotonylfentanyl, into, schedule, legal, statusleg. Crotonylfentanyl is an opioid analgesic that is an analog of fentanyl and structural isomer of cyclopropylfentanyl 1 and has been sold online as a designer drug 2 3 In December 2019 the UNODC announced scheduling recommendations placing crotonylfentanyl into Schedule I 4 CrotonylfentanylLegal statusLegal statusCA Schedule I DE Anlage II Authorized trade only not prescriptible UK Class A UN Narcotic Schedule IIdentifiersIUPAC name 2E N Phenyl N 1 2 phenylethyl 4 piperidinyl 2 butenamideCAS Number760930 59 4 YPubChem CID10472960ChemSpider8648371UNIIR0XLG8CO63Chemical and physical dataFormulaC 23H 28N 2OMolar mass348 490 g mol 13D model JSmol Interactive imageSMILES O C C C C N c1ccccc1 C3CCN CCc2ccccc2 CC3InChI InChI 1S C23H28N2O c1 2 9 23 26 25 21 12 7 4 8 13 21 22 15 18 24 19 16 22 17 14 20 10 5 3 6 11 20 h2 13 22H 14 19H2 1H3 b9 2 Key VDYXGPCGBKLRDA XNWCZRBMSA NInChI 1 C23H28N2O c1 2 9 23 26 25 21 12 7 4 8 13 21 22 15 18 24 19 16 22 17 14 20 10 5 3 6 11 20 h2 13 22H 14 19H2 1H3 b9 2 Key VDYXGPCGBKLRDA XNWCZRBMBFSee also EditValerylfentanyl AcrylfentanylReferences Edit Mallette Jennifer R Casale John F Hays Patrick A January 2019 Characterization and differentiation of cyclopropylfentanyl from E crotonylfentanyl Z crotonylfentanyl and 3 butenylfentanyl Science amp Justice 59 1 67 74 doi 10 1016 j scijus 2018 07 005 ISSN 1355 0306 PMID 30654970 S2CID 58646707 Varshneya Neil B Walentiny D Matthew Moisa Lea T Walker Teneille D Akinfiresoye Luli R Beardsley Patrick M June 2019 Opioid like antinociceptive and locomotor effects of emerging fentanyl related substances Neuropharmacology 151 171 179 doi 10 1016 j neuropharm 2019 03 023 ISSN 0028 3908 PMC 8992608 PMID 30904478 S2CID 84182661 Palaty J Konforte D Karakosta T Wong E Stefan C March 2018 Rapid identification of cyclopropyl fentanyl crotonyl fentanyl in clinical urine specimens A case study of clinical laboratory collaboration in Canada Clinical Biochemistry 53 164 167 doi 10 1016 j clinbiochem 2018 01 013 PMID 29395089 December 2019 WHO World Health Organization recommends 12 NPS for scheduling Retrieved from https en wikipedia org w index php title Crotonylfentanyl amp oldid 1095884239, wikipedia, wiki, book, books, library,

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