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Complement receptor of the immunoglobulin family

Complement receptor of the immunoglobulin family is a protein expressed in Kupffer cells.[1] It is a critical receptor for the phagocytosis of opsonised particles in the blood. It recognizes iC3b (inactivated C3b) deposited on microbial surfaces.

V-set and immunoglobulin domain containing 4
Identifiers
SymbolVSIG4
NCBI gene11326
HGNC17032
OMIM300353
RefSeqNM_007268
UniProtQ9Y279
Other data
LocusChr. X q12-q13.3
Search for
StructuresSwiss-model
DomainsInterPro

See also edit

References edit

  1. ^ Helmy K, Katschke K, Gorgani N, Kljavin N, Elliott J, Diehl L, Scales S, Ghilardi N, van Lookeren Campagne M (2006). "CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens". Cell. 124 (5): 915–27. doi:10.1016/j.cell.2005.12.039. PMID 16530040.

complement, receptor, immunoglobulin, family, protein, expressed, kupffer, cells, critical, receptor, phagocytosis, opsonised, particles, blood, recognizes, ic3b, inactivated, deposited, microbial, surfaces, immunoglobulin, domain, containing, 4identifierssymb. Complement receptor of the immunoglobulin family is a protein expressed in Kupffer cells 1 It is a critical receptor for the phagocytosis of opsonised particles in the blood It recognizes iC3b inactivated C3b deposited on microbial surfaces V set and immunoglobulin domain containing 4IdentifiersSymbolVSIG4NCBI gene11326HGNC17032OMIM300353RefSeqNM 007268UniProtQ9Y279Other dataLocusChr X q12 q13 3Search forStructuresSwiss modelDomainsInterProSee also editcomplement system immunoglobulinReferences edit Helmy K Katschke K Gorgani N Kljavin N Elliott J Diehl L Scales S Ghilardi N van Lookeren Campagne M 2006 CRIg a macrophage complement receptor required for phagocytosis of circulating pathogens Cell 124 5 915 27 doi 10 1016 j cell 2005 12 039 PMID 16530040 nbsp This article on a gene on the human X chromosome and or its associated protein is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Complement receptor of the immunoglobulin family amp oldid 1079568190, wikipedia, wiki, book, books, library,

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