ic3b, protein, fragment, that, part, complement, system, component, vertebrate, immune, system, produced, when, complement, factor, cleaves, complement, receptors, white, blood, cells, able, bind, functions, opsonin, unlike, intact, cannot, associate, with, fa. iC3b is a protein fragment that is part of the complement system a component of the vertebrate immune system iC3b is produced when complement factor I cleaves C3b 1 Complement receptors on white blood cells are able to bind iC3b so iC3b functions as an opsonin Unlike intact C3b iC3b cannot associate with factor B thus preventing amplification of the complement cascade through the alternative pathway Complement factor I can further cleave iC3b into a protein fragment known as C3d References edit Robbins Basic Pathology 8th ed 2007 R Cotran S Robbins V Kumar J Perkins W B Saunders Company nbsp This biochemistry article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title IC3b amp oldid 904352416, wikipedia, wiki, book, books, library,