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Wikipedia

Climazolam

Climazolam[1] (Ro21-3982) was introduced under licence as a veterinary medicine by the Swiss Pharmaceutical company Gräub under the tradename Climasol.[2] Climazolam is a benzodiazepine, specifically an imidazobenzodiazepine derivative developed by Hoffman-LaRoche. It is similar in structure to midazolam and diclazepam and is used in veterinary medicine for anesthetizing animals.[3][4]

Climazolam
Clinical data
Trade namesClimasol
AHFS/Drugs.comInternational Drug Names
ATCvet code
Legal status
Legal status
Identifiers
  • 8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine
CAS Number
  • 59467-77-5
PubChem CID
  • 68790
ChemSpider
  • 62030
UNII
  • O9KZB9HG1Y
KEGG
  • D07714
ChEMBL
  • ChEMBL2104070
CompTox Dashboard (EPA)
  • DTXSID30208173
Chemical and physical data
FormulaC18H13Cl2N3
Molar mass342.22 g·mol−1
3D model (JSmol)
  • Interactive image
  • ClC1=CC=CC=C1C2=NCC3=CN=C(C)N3C4=C2C=C(C=C4)Cl

References

  1. ^ US 4280957, Walser A, Fryer RI, "Imidazodiazepines and processes therefor", issued 28 July 1981, assigned to Hoffman La Roche 
  2. ^ "Climazolam". Drugs.com.
  3. ^ Ganter M, Kanngiesser M (Aug 1991). "Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine". Zentralbl Veterinarmed A (in German). 38 (7): 501–509. doi:10.1111/j.1439-0442.1991.tb01041.x. PMID 1950241.
  4. ^ Bettschart-Wolfensberger R, Taylor PM, Sear JW, Bloomfield MR, Rentsch K, Dawling S (Oct 1996). "Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine". American Journal of Veterinary Research. 57 (10): 1472–1477. PMID 8896687.


climazolam, ro21, 3982, introduced, under, licence, veterinary, medicine, swiss, pharmaceutical, company, gräub, under, tradename, climasol, benzodiazepine, specifically, imidazobenzodiazepine, derivative, developed, hoffman, laroche, similar, structure, midaz. Climazolam 1 Ro21 3982 was introduced under licence as a veterinary medicine by the Swiss Pharmaceutical company Graub under the tradename Climasol 2 Climazolam is a benzodiazepine specifically an imidazobenzodiazepine derivative developed by Hoffman LaRoche It is similar in structure to midazolam and diclazepam and is used in veterinary medicine for anesthetizing animals 3 4 ClimazolamClinical dataTrade namesClimasolAHFS Drugs comInternational Drug NamesATCvet codeQN05CD90 WHO Legal statusLegal statusCA Schedule IVIdentifiersIUPAC name 8 Chloro 6 2 chlorophenyl 1 methyl 4H imidazo 1 5 a 1 4 benzodiazepineCAS Number59467 77 5PubChem CID68790ChemSpider62030UNIIO9KZB9HG1YKEGGD07714ChEMBLChEMBL2104070CompTox Dashboard EPA DTXSID30208173Chemical and physical dataFormulaC 18H 13Cl 2N 3Molar mass342 22 g mol 13D model JSmol Interactive imageSMILES ClC1 CC CC C1C2 NCC3 CN C C N3C4 C2C C C C4 ClReferences Edit US 4280957 Walser A Fryer RI Imidazodiazepines and processes therefor issued 28 July 1981 assigned to Hoffman La Roche Climazolam Drugs com Ganter M Kanngiesser M Aug 1991 Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine Zentralbl Veterinarmed A in German 38 7 501 509 doi 10 1111 j 1439 0442 1991 tb01041 x PMID 1950241 Bettschart Wolfensberger R Taylor PM Sear JW Bloomfield MR Rentsch K Dawling S Oct 1996 Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam ketamine combination in ponies premedicated with acepromazine and xylazine American Journal of Veterinary Research 57 10 1472 1477 PMID 8896687 This sedative related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Climazolam amp oldid 989611875, wikipedia, wiki, book, books, library,

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