Celltech Group plc was a leading British-based biotechnology business based in Slough. It was listed on the London Stock Exchange and was a constituent of the FTSE 100 Index. Celltech was instrumental in changing the UK's system of technology transfer from research to business, and in creating the biotechnology industry. [1]
Celltech was formed in 1980 in response to the concern that Britain was failing to commercialise its science and was missing out on the potential of the new biotechnology. There was especial concern that whereas US firms had been creating rapidly growing firms such as Genentech around scientific discoveries in biotechnology, the UK had missed opportunities such as that believed to be provided by the Nobel Prize-winning discovery of the production technique for Monoclonal antibody by Cesar Milstein and Georges Kohler at Cambridge University.[2]
The creation of Celltech was complicated, involving the National Enterprise Board, the National Research Development Corporation, and the Medical Research Council. The decision was made to give Celltech exclusive rights to all biotechnology discoveries in UK research institutions and universities. Although the company was conceived under a Labour Government it was born under a Conservative government, with the Minister responsible, Sir Keith Joseph, being particularly averse to government intervention in industry. As a result, he ensured the company was majority owned by the private sector. The company thus began life with very high expectations: first, that a small start up could successfully commercialise the UK's scientific output in biotechnology, and second, that it could meet the profit expectations of private sector investors.[3]
Celltech's founding CEO was Gerard Fairtlough, who worked in the National Enterprise Board and saw the opportunities presented by biotechnology. He created the plan for Celltech and when the Board was created, it believed he was the best person to lead it. Fairtlough was an inspirational leader with innovative ideas on organisation. [4] In the decade that Fairtlough led Celltech, he not only helped found a significant scientific endeavour whose example led to improved ambition and ability to commercialise UK research, but introduced a new way of organising high technology firms.[5]
In 1999 Celltech led consolidation in the UKbiosciences market merging with Chiroscience plc, after which it was briefly referred to as Celltech Chiroscience,[6][7] and then buying Medeva plc.[8] Then in 2000 it bought Cistron, a USbiosciences business.[9] It expanded into Germany in 2001 buying Thiemann, a German biosciences business,[10] and went on to buy Oxford Glycosciences in July 2003 for £102m.[11] Celltech was acquired by UCB, a Belgian drugmaker, in 2004.[12]
OperationsEdit
The Company was engaged in research and development of therapies for patients with serious diseases. Products included:[13]
Amongst the work conducted at Celltech was the cloning of the glutamine synthetase (GS) gene in CHO cells leading to the creation of a biotechnology tool still widely used to express recombinant eukaryotic proteins.[15]
^ <Dodgson, M. (1990) "The Shock of the New: the formation of Celltech and the British technology transfer system, Industry and Higher Education, 4,2:97-104.
^ Dodgson, M. (1990) "The Shock of the New: the formation of Celltech and the British technology transfer system, Industry and Higher Education, 4,2:97-104.
^ Dodgson, M. (1990) Celltech: The First Ten Years of A Biotechnology Company, Discussion Paper Series, Science Policy Research Unit, University of Sussex, February 1990.
^ Fairtlough, G. (1994), 'Innovation and Organisation', in Dodgson, M. and Rothwell, R. (1994), The Handbook of Industrial Innovation, Cheltenham, Edward Elgar.
^ Dodgson, M. (1991) The Management of Technological Learning, Berlin, De Gruyter.
^Macalister, Terry (19 January 2000). "Biotech sector finds new life". The Guardian. London, England: Guardian Newspapers Ltd. p. 27. Retrieved 24 December 2018 – via Newspapers.com.
^Finch, Julia (16 June 1999). "£700m merger fuels biotech 'arms race'". The Guardian. London, England. p. 21. Retrieved 24 December 2018 – via Newspapers.com.
^UK Biotech Industry Consolidates As Celltech Buys Medeva for $915m[permanent dead link]
^"Celltech sold to Belgian firm in £1.5bn deal". The Guardian. 18 May 2004.
^Businessweek: Celltech Group September 8, 2012, at the Wayback Machine
^Damle, NK; Frost, P (August 2003). "Antibody-targeted chemotherapy with immunoconjugates of calicheamicin". Current Opinion in Pharmacology. 3 (4): 386–90. doi:10.1016/S1471-4892(03)00083-3. PMID 12901947.
^Vuksanaj, Kathy (4 October 2021). "A British Biotech Biopedia: Early Days in the U.K."
October 23, 2023
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Celltech Group plc was a leading British based biotechnology business based in Slough It was listed on the London Stock Exchange and was a constituent of the FTSE 100 Index Celltech was instrumental in changing the UK s system of technology transfer from research to business and in creating the biotechnology industry 1 Celltech GroupTypePublicIndustryBiotechnologyFounded1980Defunct2004FateAcquiredSuccessorUCBHeadquartersSlough UKKey peopleGoran Ando CEO Contents 1 History 2 Operations 3 See also 4 ReferencesHistory EditCelltech was formed in 1980 in response to the concern that Britain was failing to commercialise its science and was missing out on the potential of the new biotechnology There was especial concern that whereas US firms had been creating rapidly growing firms such as Genentech around scientific discoveries in biotechnology the UK had missed opportunities such as that believed to be provided by the Nobel Prize winning discovery of the production technique for Monoclonal antibody by Cesar Milstein and Georges Kohler at Cambridge University 2 The creation of Celltech was complicated involving the National Enterprise Board the National Research Development Corporation and the Medical Research Council The decision was made to give Celltech exclusive rights to all biotechnology discoveries in UK research institutions and universities Although the company was conceived under a Labour Government it was born under a Conservative government with the Minister responsible Sir Keith Joseph being particularly averse to government intervention in industry As a result he ensured the company was majority owned by the private sector The company thus began life with very high expectations first that a small start up could successfully commercialise the UK s scientific output in biotechnology and second that it could meet the profit expectations of private sector investors 3 Celltech s founding CEO was Gerard Fairtlough who worked in the National Enterprise Board and saw the opportunities presented by biotechnology He created the plan for Celltech and when the Board was created it believed he was the best person to lead it Fairtlough was an inspirational leader with innovative ideas on organisation 4 In the decade that Fairtlough led Celltech he not only helped found a significant scientific endeavour whose example led to improved ambition and ability to commercialise UK research but introduced a new way of organising high technology firms 5 In 1999 Celltech led consolidation in the UK biosciences market merging with Chiroscience plc after which it was briefly referred to as Celltech Chiroscience 6 7 and then buying Medeva plc 8 Then in 2000 it bought Cistron a US biosciences business 9 It expanded into Germany in 2001 buying Thiemann a German biosciences business 10 and went on to buy Oxford Glycosciences in July 2003 for 102m 11 Celltech was acquired by UCB a Belgian drugmaker in 2004 12 Operations EditThe Company was engaged in research and development of therapies for patients with serious diseases Products included 13 Tussionex for coughs Zaroxolyn for resistant edema Methylphenidate for ADHD Amphetamine for ADHD and narcolepsy as 5 mg Dexedrine tablets Semprex D an antihistamine and decongestant Inotuzumab ozogamicin and gemtuzumab ozogamicin both through Celltech s collaboration with Wyeth 14 Amongst the work conducted at Celltech was the cloning of the glutamine synthetase GS gene in CHO cells leading to the creation of a biotechnology tool still widely used to express recombinant eukaryotic proteins 15 See also EditPharmaceutical industry in the United KingdomReferences Edit lt Dodgson M 1990 The Shock of the New the formation of Celltech and the British technology transfer system Industry and Higher Education 4 2 97 104 Dodgson M 1990 The Shock of the New the formation of Celltech and the British technology transfer system Industry and Higher Education 4 2 97 104 Dodgson M 1990 Celltech The First Ten Years of A Biotechnology Company Discussion Paper Series Science Policy Research Unit University of Sussex February 1990 Fairtlough G 1994 Innovation and Organisation in Dodgson M and Rothwell R 1994 The Handbook of Industrial Innovation Cheltenham Edward Elgar Dodgson M 1991 The Management of Technological Learning Berlin De Gruyter Macalister Terry 19 January 2000 Biotech sector finds new life The Guardian London England Guardian Newspapers Ltd p 27 Retrieved 24 December 2018 via Newspapers com Finch Julia 16 June 1999 700m merger fuels biotech arms race The Guardian London England p 21 Retrieved 24 December 2018 via Newspapers com UK Biotech Industry Consolidates As Celltech Buys Medeva for 915m permanent dead link UK s Celltech Buys Cistron of the US permanent dead link Celltech acquires German sales and marketing firm Thiemann for 44 6 m www thepharmaletter com Archived from the original on 11 April 2013 ISIS Archived September 17 2014 at the Wayback Machine Celltech sold to Belgian firm in 1 5bn deal The Guardian 18 May 2004 Businessweek Celltech Group Archived September 8 2012 at the Wayback Machine Damle NK Frost P August 2003 Antibody targeted chemotherapy with immunoconjugates of calicheamicin Current Opinion in Pharmacology 3 4 386 90 doi 10 1016 S1471 4892 03 00083 3 PMID 12901947 Vuksanaj Kathy 4 October 2021 A British Biotech Biopedia Early Days in the U K Retrieved from https en wikipedia org w index php title Celltech amp oldid 1163183935, wikipedia, wiki, book, books, library,
