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Caspar Friedrich Wolff

Caspar Friedrich Wolff (18 January 1733 – 22 February 1794) was a German physiologist and embryologist who is widely regarded as one of the pioneers of modern embryology.

Caspar Friedrich Wolff
Caspar Friedrich Wolff, a silhouette by F. Anting (1784), one of the two known portraits of Wolff
Born18 January 1733
Died22 February 1794 (1794-02-23) (aged 61)
NationalityGerman
Alma materUniversity of Halle
Known forgynécologue
Scientific career
Fieldsgynécologue
Signature

Life edit

Wolff was born in Berlin, Brandenburg. In 1759 he graduated as an M.D. from the University of Halle with his dissertation "Theoria Generationis", where he revived and supported the theory of epigenesis previously proposed by Aristotle and William Harvey. The paper consisted of three parts devoted to (1) development of plants, (2) development of animals, and (3) theoretical considerations. It indicated that organs are formed in differentiated layers from undifferentiated cells. Traditional and prevailing theory had speculated that organisms were already preformed in the seed (theory of preformation), that is in the human a homunculus was already sitting in the sperm. His views were not well received. Albrecht von Haller was a powerful antagonist. During the Seven Years' War, Wolff was required to practice as a field doctor in the Prussian Army. Thereafter he had difficulty entering academic life. Finally, in 1767, with help of the mathematician Leonhard Euler he obtained the chairmanship of anatomy at the St.Petersburg Academy of Sciences (now Russian Academy of Sciences). He died in Saint Petersburg.

Research edit

 
C. F. Wolff, attribution of the portrait dubious.

Wolff's research covered embryology, anatomy, and botany. He was the discoverer of the primitive kidneys (mesonephros), or "Wolffian bodies" and its excretory ducts. He described these in his dissertation "Theoria Generationis" after observing them in his studies on chick embryos. According to Locy, since he assumed a total lack of organization in the beginning, he was obliged to make development "miraculous" through the action on the egg of a hyperphysical agent; from a total lack of organization, he conceived of its being lifted to the highly organized product through the action of a "vis essentialis corporis." In 1768–1769, he published his best work in embryology on the development of the intestine; of which Baer said, "It is the greatest masterpiece of scientific observation which we possess." Again, according to Locy, while Wolff's investigations for "Theoria Generationis" did not reach the level of Marcello Malpighi’s, those of the paper of 1768 surpassed them and held the position of the best piece of embryological work up to that of Heinz Christian Pander and Karl Ernst von Baer.

Wolff’s "De Formatione Intestinorum" rather than his "Theoria Generationis" embodies his greatest contribution to embryology; in it he foreshadows the idea of germ layers in the embryo, which, under Pander and von Baer, became the fundamental conception in structural embryology—he laid the foundation for the germ layer theory. Wolff foreshadowed the germ layer theory by showing that the material out of which the embryo is constructed is, in an early stage of development, arranged in the form of leaf-like layers. Locy recognizes Wolff as the foremost investigator in embryology before von Baer. Wolff contended that the organs of animals make their appearance gradually and that he could actually follow their successive stages of formation.(Dye)

Eponyms edit

Wolff's eponyms are:

  1. Wolffian ducts or mesonephric ducts
  2. Wolffian cysts
  3. Wolffian body or mesonephros
  4. Wolff's islands or blood islands

References edit

  1. William A. Locy, Biology and its Makers, Henry Holt and Company, New York, 1908
  2. Frank J. Dye, Dictionary of Developmental Biology and Embryology, Wiley-Liss, New York, 2002
  3. Speert H. Obstetrical and Gynecological Milestones. The Macmillan C., New York, 1958.
  4. Medical eponyms

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You can help expand this article with text translated from the corresponding article in German March 2023 Click show for important translation instructions View a machine translated version of the German article Machine translation like DeepL or Google Translate is a useful starting point for translations but translators must revise errors as necessary and confirm that the translation is accurate rather than simply copy pasting machine translated text into the English Wikipedia Consider adding a topic to this template there are already 9 121 articles in the main category and specifying topic will aid in categorization Do not translate text that appears unreliable or low quality If possible verify the text with references provided in the foreign language article You must provide copyright attribution in the edit summary accompanying your translation by providing an interlanguage link to the source of your translation A model attribution edit summary is Content in this edit is translated from the existing German Wikipedia article at de Caspar Friedrich Wolff see its history for attribution You may also add the template Translated de Caspar Friedrich Wolff to the talk page For more guidance see Wikipedia Translation This article includes a list of references related reading or external links but its sources remain unclear because it lacks inline citations Please help improve this article by introducing more precise citations April 2014 Learn how and when to remove this message Caspar Friedrich Wolff 18 January 1733 22 February 1794 was a German physiologist and embryologist who is widely regarded as one of the pioneers of modern embryology Caspar Friedrich WolffCaspar Friedrich Wolff a silhouette by F Anting 1784 one of the two known portraits of WolffBorn18 January 1733Berlin BrandenburgDied22 February 1794 1794 02 23 aged 61 Saint Petersburg Russian EmpireNationalityGermanAlma materUniversity of HalleKnown forgynecologueScientific careerFieldsgynecologueSignatureContents 1 Life 2 Research 2 1 Eponyms 3 ReferencesLife editWolff was born in Berlin Brandenburg In 1759 he graduated as an M D from the University of Halle with his dissertation Theoria Generationis where he revived and supported the theory of epigenesis previously proposed by Aristotle and William Harvey The paper consisted of three parts devoted to 1 development of plants 2 development of animals and 3 theoretical considerations It indicated that organs are formed in differentiated layers from undifferentiated cells Traditional and prevailing theory had speculated that organisms were already preformed in the seed theory of preformation that is in the human a homunculus was already sitting in the sperm His views were not well received Albrecht von Haller was a powerful antagonist During the Seven Years War Wolff was required to practice as a field doctor in the Prussian Army Thereafter he had difficulty entering academic life Finally in 1767 with help of the mathematician Leonhard Euler he obtained the chairmanship of anatomy at the St Petersburg Academy of Sciences now Russian Academy of Sciences He died in Saint Petersburg Research edit nbsp C F Wolff attribution of the portrait dubious Wolff s research covered embryology anatomy and botany He was the discoverer of the primitive kidneys mesonephros or Wolffian bodies and its excretory ducts He described these in his dissertation Theoria Generationis after observing them in his studies on chick embryos According to Locy since he assumed a total lack of organization in the beginning he was obliged to make development miraculous through the action on the egg of a hyperphysical agent from a total lack of organization he conceived of its being lifted to the highly organized product through the action of a vis essentialis corporis In 1768 1769 he published his best work in embryology on the development of the intestine of which Baer said It is the greatest masterpiece of scientific observation which we possess Again according to Locy while Wolff s investigations for Theoria Generationis did not reach the level of Marcello Malpighi s those of the paper of 1768 surpassed them and held the position of the best piece of embryological work up to that of Heinz Christian Pander and Karl Ernst von Baer Wolff s De Formatione Intestinorum rather than his Theoria Generationis embodies his greatest contribution to embryology in it he foreshadows the idea of germ layers in the embryo which under Pander and von Baer became the fundamental conception in structural embryology he laid the foundation for the germ layer theory Wolff foreshadowed the germ layer theory by showing that the material out of which the embryo is constructed is in an early stage of development arranged in the form of leaf like layers Locy recognizes Wolff as the foremost investigator in embryology before von Baer Wolff contended that the organs of animals make their appearance gradually and that he could actually follow their successive stages of formation Dye Eponyms edit Wolff s eponyms are Wolffian ducts or mesonephric ducts Wolffian cysts Wolffian body or mesonephros Wolff s islands or blood islandsReferences editWilliam A Locy Biology and its Makers Henry Holt and Company New York 1908 Frank J Dye Dictionary of Developmental Biology and Embryology Wiley Liss New York 2002 Speert H Obstetrical and Gynecological Milestones The Macmillan C New York 1958 Medical eponyms Retrieved from https en wikipedia org w index php title Caspar Friedrich Wolff amp oldid 1190038684, wikipedia, wiki, book, books, library,

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