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CP-226,269

CP-226,269 is a drug which acts as a dopamine agonist selective for the D4 subtype, which is used for researching the role of D4 receptors in the brain.[1][2]

CP-226,269
Identifiers
  • 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole
CAS Number
  • 220941-93-5 N
PubChem CID
  • 9796720
IUPHAR/BPS
  • 973
ChemSpider
  • 7972486 Y
UNII
  • WX4CVT9DYH
ChEMBL
  • ChEMBL77395 Y
CompTox Dashboard (EPA)
  • DTXSID70430875
Chemical and physical data
FormulaC18H19FN4
Molar mass310.376 g·mol−1
3D model (JSmol)
  • Interactive image
  • n4ccccc4N3CCN(CC3)Cc2cc1cc(F)ccc1[nH]2
  • InChI=1S/C18H19FN4/c19-15-4-5-17-14(11-15)12-16(21-17)13-22-7-9-23(10-8-22)18-3-1-2-6-20-18/h1-6,11-12,21H,7-10,13H2 Y
  • Key:PQOIDBZLMJMYCD-UHFFFAOYSA-N Y
 NY (what is this?)  (verify)

References edit

  1. ^ Sharma A, Kramer ML, Wick PF, Liu D, Chari S, Shim S, Tan W, Ouellette D, Nagata M, DuRand CJ, Kotb M, Deth RC (May 1999). "D4 dopamine receptor-mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia". Molecular Psychiatry. 4 (3): 235–46. doi:10.1038/sj.mp.4000522. PMID 10395213.
  2. ^ Basso AM, Gallagher KB, Bratcher NA, Brioni JD, Moreland RB, Hsieh GC, Drescher K, Fox GB, Decker MW, Rueter LE (July 2005). "Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test". Neuropsychopharmacology. 30 (7): 1257–68. doi:10.1038/sj.npp.1300677. PMID 15688083.

drug, which, acts, dopamine, agonist, selective, subtype, which, used, researching, role, receptors, brain, identifiersiupac, name, fluoro, pyridin, ylpiperazin, methyl, indolecas, number220941, npubchem, cid9796720iuphar, bps973chemspider7972486, yuniiwx4cvt9. CP 226 269 is a drug which acts as a dopamine agonist selective for the D4 subtype which is used for researching the role of D4 receptors in the brain 1 2 CP 226 269IdentifiersIUPAC name 5 fluoro 2 4 pyridin 2 ylpiperazin 1 yl methyl 1H indoleCAS Number220941 93 5 NPubChem CID9796720IUPHAR BPS973ChemSpider7972486 YUNIIWX4CVT9DYHChEMBLChEMBL77395 YCompTox Dashboard EPA DTXSID70430875Chemical and physical dataFormulaC 18H 19F N 4Molar mass310 376 g mol 13D model JSmol Interactive imageSMILES n4ccccc4N3CCN CC3 Cc2cc1cc F ccc1 nH 2InChI InChI 1S C18H19FN4 c19 15 4 5 17 14 11 15 12 16 21 17 13 22 7 9 23 10 8 22 18 3 1 2 6 20 18 h1 6 11 12 21H 7 10 13H2 YKey PQOIDBZLMJMYCD UHFFFAOYSA N Y N Y what is this verify References edit Sharma A Kramer ML Wick PF Liu D Chari S Shim S Tan W Ouellette D Nagata M DuRand CJ Kotb M Deth RC May 1999 D4 dopamine receptor mediated phospholipid methylation and its implications for mental illnesses such as schizophrenia Molecular Psychiatry 4 3 235 46 doi 10 1038 sj mp 4000522 PMID 10395213 Basso AM Gallagher KB Bratcher NA Brioni JD Moreland RB Hsieh GC Drescher K Fox GB Decker MW Rueter LE July 2005 Antidepressant like effect of D 2 3 receptor but not D 4 receptor activation in the rat forced swim test Neuropsychopharmacology 30 7 1257 68 doi 10 1038 sj npp 1300677 PMID 15688083 nbsp This drug article relating to the nervous system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title CP 226 269 amp oldid 1190948624, wikipedia, wiki, book, books, library,

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