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Bladder stone

A bladder stone is a stone found in the urinary bladder.[1]

Bladder stone
Other namesvesical calculus, cystolith
A bladder stone removed from a patient.
SpecialtyUrology 
SymptomsPain when urinating
ComplicationsCystitis
CausesOverconcentration of minerals, dehydration
PreventionDrinking plenty of fluids
TreatmentCitrus juice, vinegar, surgery

Signs and symptoms edit

 
Bladder stones (14 mm diameter) incidentally found in a bladder diverticulum during transvesical prostatectomy (removal of the prostate via an incision in the bladder)

Bladder stones are small mineral deposits that can form in the bladder. In most cases bladder stones develop when the urine becomes very concentrated or when one is dehydrated. This allows for minerals, such as calcium or magnesium salts, to crystallize and form stones. Bladder stones vary in number, size and consistency. In some cases bladder stones do not cause any symptoms and are discovered as an incidental finding on a plain radiograph. However, when symptoms do occur, these may include severe lower abdominal and back pain, difficult urination, frequent urination at night, fever, painful urination and blood in the urine. The majority of individuals who are symptomatic will complain of pain which comes in waves. The pain may also be associated with nausea, vomiting and chills.[2]

Bladder stones vary in their size, shape and texture- some are small, hard and smooth whereas others are huge, spiked and very soft. One can have one or multiple stones. Bladder stones are somewhat more common in men who have prostate enlargement. The large prostate presses on the urethra and makes it difficult to pass urine. Over time, stagnant urine collects in the bladder and minerals like calcium start to precipitate. Other individuals who develop bladder stones include those who have had spinal cord injury, paralysis, or some type of nerve damage. When nerves to the back are damaged, the bladder cannot empty, resulting in stagnant urine.[3]

Causes edit

Bladder stones may occur whenever the kidneys, bladder, or ureters become inflamed, which may occur when the urine becomes too concentrated or when the body becomes dehydrated. Minerals such as calcium and magnesium crystallize into the stones, which then can cause such symptoms as lower back or abdominal pain or difficulty with urination. The use of urinary catheters may cause a bladder stone. Individuals who are paralyzed or are unable to adequately pass urine may require the use of small plastic tubes (catheters) placed into the bladder. The use of these tubes may lead to an infection, which irritates the bladder, resulting in stone formation. Finally, a kidney stone may travel down the ureter into the bladder and become a bladder stone. There is some evidence indicating that chronic irritation of the bladder by retained stones may increase the chance of bladder cancer. Urinary schistosomiasis, a disease caused by the digenean trematode Schistosoma haematobium, has been implicated in the development of vesical calculi.[4][5] However, evidence accumulated thus far has not supported this hypothesis.[6][7]

Diagnosis edit

 
Large jackstone in the bladder of a 60-year-old man. Stone was removed by open cystolithotomy

The diagnosis of bladder stone includes urinalysis, ultrasonography, x rays or cystoscopy (inserting a small thin camera into the urethra and viewing the bladder). The intravenous pyelogram can also be used to assess the presence of kidney stones. This test involves injecting a radiocontrast agent which is passed into the urinary system. X-ray images are then obtained every few minutes to determine if there is any obstruction to the contrast as it is excreted into the bladder. Today, intravenous pyelogram has been replaced at many health centers by CT scans. CT scans are more sensitive and can identify very small stones not seen by other tests.[8]

Classification edit

 
A star-shaped Jackstone urolith can be seen in the urinary bladder on this radiograph of the pelvis

Urinary stones may be composed of the following substances:[9]

Jackstone calculus edit

Jackstone calculi are rare bladder stones that have an appearance resembling toy jacks. They are almost always composed of calcium oxalate dihydrate and consist of a dense central core and radiating spicules. They are typically light brown with dark patches and are usually formed in the urinary bladder and rarely in the upper urinary tract. Their appearance on plain radiographs and computed tomography in human patients is usually easily recognizable. Jackstones often must be removed via cystolithotomy.[10]

Prevention edit

The best way to prevent bladder stones is to drink plenty of liquids. Juices containing citrates are thought to reduce the risk of stone formation. A study published in the Clinical Journal of the American Society of Nephrology indicate orange juice is more effective at preventing stone formation than other citrus juices.[11] Men who have difficulty with urination due to prostate enlargement should seek treatment,[12] however, urinating in a sitting position appears to improve bladder emptying which might decrease the risk of bladder stones forming.[13]

Prevention in newborn children, especially in the first three months of life when most stones begin, is critical. Studies show that feeding newborn infants milk (mother's, cow or goat) with no substitutes or supplements until at least the third month has proven successful in preventing most stones.[14]

Management edit

Increasing fluid intake can facilitate the passage of small bladder stones. However, larger stones may require other methods of treatment.[15] Fragmentation of bladder stones can be achieved by use of a cystoscope which is inserted into the bladder. The urologist visualizes the stone and uses ultrasonic energy or laser lithotripsy to cause fragmentation of the stones into small pieces, which are then flushed out of the bladder. This procedure requires anesthesia and may require admission to a hospital. Complications of this treatment include infection and damage to the bladder.[16] Some stones are too large even for cystoscopic treatment and may require open cystotomy, in which an incision is made in the bladder and the stones are removed manually. For children with urinary stones, the evidence supporting treatment options is very weak and high quality trials are necessary to help guide clinical management.[17]

Cystolithotomy edit

Cystolithotomy is a surgical procedure for the removal of bladder stones in the case that one has been deemed too large to pass naturally, such as developed jackstone calculi. This may require open surgery to remove the stone, however robotic cystolithotomy allows for a minimally invasive approach to remove the stone through much smaller incisions than the traditional approach. Most bladder stones can be dealt with by an endoscopic procedure, to avoid the need for a surgical incision.

An open cystolithotomy is performed under general anesthesia as an inpatient procedure. The first step is a cystoscopy to examine the bladder, then an incision is made in the lower abdomen. Once the stone is removed, the bladder is repaired with an absorbable stitch, and a catheter is inserted into the bladder via the urethra. Occasionally it is necessary to gently drip fluid in and out of the bladder for a period, as there is often some bleeding following the procedure. The majority of patients do not have major side effects following cystolithotomy, but it may be followed by a minor burning sensation and light bleeding. More serious side effects include bladder infection, a prolonged need of catheter use, and infection in the surgical incision. Rare side effects may include delayed bleeding requiring removal of clots or further surgery, injury to the urethra causing scar formation, fever and more serious infection requiring a longer hospital stay, and delayed healing of the bladder, which may require a further procedure.[18]

History edit

 
Portrait of Jan de Doot, by Carel van Savoyen, holding the bladder stone he removed from himself according to a 1652 account in the book Observationes Medicae by Nicolaes Tulp

Lithoclastic cystotomy is attributed to Ammonius Lithotomos (stone-cutter) of Alexandria, Egypt. The term "lithotomy" is derived from the same words (λιθοτομία (lithotomia) - stone-cutting). Aulus Cornelius Celsus wrote that Lithotomos developed instruments to break up and extract bladder stones.[19] Celsus gave the first description of lithotomy as performed before and during his time, and the operation has ever since borne his name—the Celsian method.[20]

Etymology edit

Lithiasis (stone formation) in the bladder is called cystolithiasis (/ˌsɪstlɪˈθəsɪs/), from cysto- (bladder/cyst) + -lith (stone) + -iasis (disorder).

See also edit

Other animals edit

References edit

  1. ^ McNutt, WF (1893). "Chapter VII: Vesical Calculi (Cysto-lithiasis)". Diseases of the kidneys and bladder: a text-book for students of medicine. Vol. IV: Diseases of the Bladder. Philadelphia: J.B. Lippincott Company. pp. 185–6. Retrieved 2011-06-04.
  2. ^ Bladder Stones General Overview 2019-04-08 at the Wayback Machine, Retrieved on 2010-01-19.
  3. ^ Bladder Stones Prevention, Retrieved on 2010-01-19.
  4. ^ Ward, RO (1945). "Some Surgical Aspects of Urinary Bilharziasis". Proceedings of the Royal Society of Medicine. 39 (1): 27–38. doi:10.1177/003591574503900105. ISSN 0035-9157. PMC 2181785. PMID 19993192.
  5. ^ Lukács, T; Frang D; El-Seaghy AA; Pajor L (1989). "Multiple urolithiasis in bilharziasis patients". International Urology and Nephrology. 21 (3): 269–73. doi:10.1007/BF02559736. PMID 2807777. S2CID 35057871.
  6. ^ Ibrahim, A (1978). "The relationship between urinary bilharziasis and urolithiasis in the Sudan". British Journal of Urology. 50 (5): 294–7. doi:10.1111/j.1464-410X.1978.tb03634.x. ISSN 0007-1331. PMID 753482.
  7. ^ Kambal, A (1981). "The Relation of Urinary Bilharziasis to Vesical Stones in Children". British Journal of Urology. 53 (4): 315. doi:10.1111/j.1464-410X.1981.tb03185.x. ISSN 0007-1331. PMID 7260543.
  8. ^ Bladder Stones: eMedicine Urology, Retrieved on 2010-01-19.
  9. ^ S. Materazzi, R. Curini, G. D'Ascenzo, and A. D. Magri (1995), TG-FTIR coupled analysis applied to the studies in urolithiasis: characterization of human renal calculi. Termochimica Acta, volume 264, 75--93.
  10. ^ Singh, KamalJeet; Goyal, Adarsh; Tiwari, Anuj (2011). "Jackstone: A rare entity of vesical calculus". Indian Journal of Urology. 27 (4): 543–4. doi:10.4103/0970-1591.91449. ISSN 0970-1591. PMC 3263228. PMID 22279326.
  11. ^ "Orange Juice Fights Kidney Stones". www.webmd.com. Retrieved 2011-04-26.
  12. ^ Bladder Stones: Prevention, Retrieved on 2010-01-19.
  13. ^ de Jong, Y; Pinckaers, JH; Ten Brinck, RM; Lycklama À Nijeholt, AA; Dekkers, OM (2014). "Urinating Standing versus Sitting: Position Is of Influence in Men with Prostate Enlargement. A Systematic Review and Meta-Analysis". PLOS ONE. 9 (7): e101320. Bibcode:2014PLoSO...9j1320D. doi:10.1371/journal.pone.0101320. PMC 4106761. PMID 25051345.
  14. ^ Halstead, Scott B. (April 2016). "Epidemiology of bladder stone of children: precipitating events". Urolithiasis. 44 (2): 101–108. doi:10.1007/s00240-015-0835-8. ISSN 2194-7236. PMID 26559057. S2CID 24890381 – via pubmed.gov.
  15. ^ Bladder Stones: NY Times Health Information, Retrieved on 2010-01-19.
  16. ^ Bladder Stones Overview: University of Maryland Medical Center, Retrieved on 2010-01-19.
  17. ^ Barreto, Lenka; Jung, Jae Hung; Abdelrahim, Ameera; Ahmed, Munir; Dawkins, Guy P. C.; Kazmierski, Marcin (2019-10-09). "Medical and surgical interventions for the treatment of urinary stones in children". The Cochrane Database of Systematic Reviews. 2019 (10): CD010784. doi:10.1002/14651858.CD010784.pub3. ISSN 1469-493X. PMC 6785002. PMID 31596944.
  18. ^ "Cystolithotomy (Open Removal of Bladder Stones)". Nicholas Brook Urology. Nick Brook Urologist Adelaide. 2013. Retrieved 17 April 2014.
  19. ^ Celsus, Aulus Cornelius (1831). A translation of the eight books of Aul. Corn. Celsus on medicine. Simpkin and Marshal. pp. 311–. Retrieved 2011-06-04.
  20. ^ Gouley, John William Severin (1892). Diseases of the urinary apparatus: phlegmasic affections. D. Appleton and Company. pp. 3–. Retrieved 2011-06-04.

External links edit

bladder, stone, urinary, stone, redirects, here, stones, which, form, upper, urinary, tract, kidney, stone, disease, this, article, about, bladder, stone, humans, bladder, stone, animals, animal, this, article, includes, list, general, references, lacks, suffi. Urinary stone redirects here For stones which form in the upper urinary tract see Kidney stone disease This article is about bladder stone in humans For bladder stone in animals see Bladder stone animal This article includes a list of general references but it lacks sufficient corresponding inline citations Please help to improve this article by introducing more precise citations December 2022 Learn how and when to remove this message A bladder stone is a stone found in the urinary bladder 1 Bladder stoneOther namesvesical calculus cystolithA bladder stone removed from a patient SpecialtyUrology SymptomsPain when urinatingComplicationsCystitisCausesOverconcentration of minerals dehydrationPreventionDrinking plenty of fluidsTreatmentCitrus juice vinegar surgery Contents 1 Signs and symptoms 2 Causes 3 Diagnosis 3 1 Classification 3 2 Jackstone calculus 4 Prevention 5 Management 5 1 Cystolithotomy 6 History 7 Etymology 8 See also 9 Other animals 10 References 11 External linksSigns and symptoms edit nbsp Bladder stones 14 mm diameter incidentally found in a bladder diverticulum during transvesical prostatectomy removal of the prostate via an incision in the bladder Bladder stones are small mineral deposits that can form in the bladder In most cases bladder stones develop when the urine becomes very concentrated or when one is dehydrated This allows for minerals such as calcium or magnesium salts to crystallize and form stones Bladder stones vary in number size and consistency In some cases bladder stones do not cause any symptoms and are discovered as an incidental finding on a plain radiograph However when symptoms do occur these may include severe lower abdominal and back pain difficult urination frequent urination at night fever painful urination and blood in the urine The majority of individuals who are symptomatic will complain of pain which comes in waves The pain may also be associated with nausea vomiting and chills 2 Bladder stones vary in their size shape and texture some are small hard and smooth whereas others are huge spiked and very soft One can have one or multiple stones Bladder stones are somewhat more common in men who have prostate enlargement The large prostate presses on the urethra and makes it difficult to pass urine Over time stagnant urine collects in the bladder and minerals like calcium start to precipitate Other individuals who develop bladder stones include those who have had spinal cord injury paralysis or some type of nerve damage When nerves to the back are damaged the bladder cannot empty resulting in stagnant urine 3 Causes editBladder stones may occur whenever the kidneys bladder or ureters become inflamed which may occur when the urine becomes too concentrated or when the body becomes dehydrated Minerals such as calcium and magnesium crystallize into the stones which then can cause such symptoms as lower back or abdominal pain or difficulty with urination The use of urinary catheters may cause a bladder stone Individuals who are paralyzed or are unable to adequately pass urine may require the use of small plastic tubes catheters placed into the bladder The use of these tubes may lead to an infection which irritates the bladder resulting in stone formation Finally a kidney stone may travel down the ureter into the bladder and become a bladder stone There is some evidence indicating that chronic irritation of the bladder by retained stones may increase the chance of bladder cancer Urinary schistosomiasis a disease caused by the digenean trematode Schistosoma haematobium has been implicated in the development of vesical calculi 4 5 However evidence accumulated thus far has not supported this hypothesis 6 7 Diagnosis edit nbsp Large jackstone in the bladder of a 60 year old man Stone was removed by open cystolithotomy The diagnosis of bladder stone includes urinalysis ultrasonography x rays or cystoscopy inserting a small thin camera into the urethra and viewing the bladder The intravenous pyelogram can also be used to assess the presence of kidney stones This test involves injecting a radiocontrast agent which is passed into the urinary system X ray images are then obtained every few minutes to determine if there is any obstruction to the contrast as it is excreted into the bladder Today intravenous pyelogram has been replaced at many health centers by CT scans CT scans are more sensitive and can identify very small stones not seen by other tests 8 Classification edit nbsp A star shaped Jackstone urolith can be seen in the urinary bladder on this radiograph of the pelvis Urinary stones may be composed of the following substances 9 Calcium oxalate monohydrate whewellite Calcium oxalate dihydrate weddellite Calcium phosphate Magnesium phosphate Ammonium phosphate Ammonium magnesium phosphate struvite Calcium hydroxyphosphate apatite Uric acid and its salts urates Cystine Xanthine Indigotin rare Urostealith rare Sulfonamide rare Jackstone calculus edit Jackstone calculi are rare bladder stones that have an appearance resembling toy jacks They are almost always composed of calcium oxalate dihydrate and consist of a dense central core and radiating spicules They are typically light brown with dark patches and are usually formed in the urinary bladder and rarely in the upper urinary tract Their appearance on plain radiographs and computed tomography in human patients is usually easily recognizable Jackstones often must be removed via cystolithotomy 10 Prevention editThe best way to prevent bladder stones is to drink plenty of liquids Juices containing citrates are thought to reduce the risk of stone formation A study published in the Clinical Journal of the American Society of Nephrology indicate orange juice is more effective at preventing stone formation than other citrus juices 11 Men who have difficulty with urination due to prostate enlargement should seek treatment 12 however urinating in a sitting position appears to improve bladder emptying which might decrease the risk of bladder stones forming 13 Prevention in newborn children especially in the first three months of life when most stones begin is critical Studies show that feeding newborn infants milk mother s cow or goat with no substitutes or supplements until at least the third month has proven successful in preventing most stones 14 Management editIncreasing fluid intake can facilitate the passage of small bladder stones However larger stones may require other methods of treatment 15 Fragmentation of bladder stones can be achieved by use of a cystoscope which is inserted into the bladder The urologist visualizes the stone and uses ultrasonic energy or laser lithotripsy to cause fragmentation of the stones into small pieces which are then flushed out of the bladder This procedure requires anesthesia and may require admission to a hospital Complications of this treatment include infection and damage to the bladder 16 Some stones are too large even for cystoscopic treatment and may require open cystotomy in which an incision is made in the bladder and the stones are removed manually For children with urinary stones the evidence supporting treatment options is very weak and high quality trials are necessary to help guide clinical management 17 Cystolithotomy edit Cystolithotomy is a surgical procedure for the removal of bladder stones in the case that one has been deemed too large to pass naturally such as developed jackstone calculi This may require open surgery to remove the stone however robotic cystolithotomy allows for a minimally invasive approach to remove the stone through much smaller incisions than the traditional approach Most bladder stones can be dealt with by an endoscopic procedure to avoid the need for a surgical incision An open cystolithotomy is performed under general anesthesia as an inpatient procedure The first step is a cystoscopy to examine the bladder then an incision is made in the lower abdomen Once the stone is removed the bladder is repaired with an absorbable stitch and a catheter is inserted into the bladder via the urethra Occasionally it is necessary to gently drip fluid in and out of the bladder for a period as there is often some bleeding following the procedure The majority of patients do not have major side effects following cystolithotomy but it may be followed by a minor burning sensation and light bleeding More serious side effects include bladder infection a prolonged need of catheter use and infection in the surgical incision Rare side effects may include delayed bleeding requiring removal of clots or further surgery injury to the urethra causing scar formation fever and more serious infection requiring a longer hospital stay and delayed healing of the bladder which may require a further procedure 18 History edit nbsp Portrait of Jan de Doot by Carel van Savoyen holding the bladder stone he removed from himself according to a 1652 account in the book Observationes Medicae by Nicolaes Tulp Lithoclastic cystotomy is attributed to Ammonius Lithotomos stone cutter of Alexandria Egypt The term lithotomy is derived from the same words li8otomia lithotomia stone cutting Aulus Cornelius Celsus wrote that Lithotomos developed instruments to break up and extract bladder stones 19 Celsus gave the first description of lithotomy as performed before and during his time and the operation has ever since borne his name the Celsian method 20 Etymology editLithiasis stone formation in the bladder is called cystolithiasis ˌ s ɪ s t oʊ l ɪ ˈ 8 aɪ e s ɪ s from cysto bladder cyst lith stone iasis disorder See also editUreter stone Kidney stone diseaseOther animals editMain article Bladder stone animal References edit McNutt WF 1893 Chapter VII Vesical Calculi Cysto lithiasis Diseases of the kidneys and bladder a text book for students of medicine Vol IV Diseases of the Bladder Philadelphia J B Lippincott Company pp 185 6 Retrieved 2011 06 04 Bladder Stones General Overview Archived 2019 04 08 at the Wayback Machine Retrieved on 2010 01 19 Bladder Stones Prevention Retrieved on 2010 01 19 Ward RO 1945 Some Surgical Aspects of Urinary Bilharziasis Proceedings of the Royal Society of Medicine 39 1 27 38 doi 10 1177 003591574503900105 ISSN 0035 9157 PMC 2181785 PMID 19993192 Lukacs T Frang D El Seaghy AA Pajor L 1989 Multiple urolithiasis in bilharziasis patients International Urology and Nephrology 21 3 269 73 doi 10 1007 BF02559736 PMID 2807777 S2CID 35057871 Ibrahim A 1978 The relationship between urinary bilharziasis and urolithiasis in the Sudan British Journal of Urology 50 5 294 7 doi 10 1111 j 1464 410X 1978 tb03634 x ISSN 0007 1331 PMID 753482 Kambal A 1981 The Relation of Urinary Bilharziasis to Vesical Stones in Children British Journal of Urology 53 4 315 doi 10 1111 j 1464 410X 1981 tb03185 x ISSN 0007 1331 PMID 7260543 Bladder Stones eMedicine Urology Retrieved on 2010 01 19 S Materazzi R Curini G D Ascenzo and A D Magri 1995 TG FTIR coupled analysis applied to the studies in urolithiasis characterization of human renal calculi Termochimica Acta volume 264 75 93 Singh KamalJeet Goyal Adarsh Tiwari Anuj 2011 Jackstone A rare entity of vesical calculus Indian Journal of Urology 27 4 543 4 doi 10 4103 0970 1591 91449 ISSN 0970 1591 PMC 3263228 PMID 22279326 Orange Juice Fights Kidney Stones www webmd com Retrieved 2011 04 26 Bladder Stones Prevention Retrieved on 2010 01 19 de Jong Y Pinckaers JH Ten Brinck RM Lycklama A Nijeholt AA Dekkers OM 2014 Urinating Standing versus Sitting Position Is of Influence in Men with Prostate Enlargement A Systematic Review and Meta Analysis PLOS ONE 9 7 e101320 Bibcode 2014PLoSO 9j1320D doi 10 1371 journal pone 0101320 PMC 4106761 PMID 25051345 Halstead Scott B April 2016 Epidemiology of bladder stone of children precipitating events Urolithiasis 44 2 101 108 doi 10 1007 s00240 015 0835 8 ISSN 2194 7236 PMID 26559057 S2CID 24890381 via pubmed gov Bladder Stones NY Times Health Information Retrieved on 2010 01 19 Bladder Stones Overview University of Maryland Medical Center Retrieved on 2010 01 19 Barreto Lenka Jung Jae Hung Abdelrahim Ameera Ahmed Munir Dawkins Guy P C Kazmierski Marcin 2019 10 09 Medical and surgical interventions for the treatment of urinary stones in children The Cochrane Database of Systematic Reviews 2019 10 CD010784 doi 10 1002 14651858 CD010784 pub3 ISSN 1469 493X PMC 6785002 PMID 31596944 Cystolithotomy Open Removal of Bladder Stones Nicholas Brook Urology Nick Brook Urologist Adelaide 2013 Retrieved 17 April 2014 Celsus Aulus Cornelius 1831 A translation of the eight books of Aul Corn Celsus on medicine Simpkin and Marshal pp 311 Retrieved 2011 06 04 Gouley John William Severin 1892 Diseases of the urinary apparatus phlegmasic affections D Appleton and Company pp 3 Retrieved 2011 06 04 External links edit nbsp Wikimedia Commons has media related to Urinary bladder stones Retrieved from https en wikipedia org w index php title Bladder stone amp oldid 1170268601, 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