For the function of calcium phosphate in organisms, see Calcium metabolism.
The term calcium phosphate refers to a family of materials and minerals containing calciumions (Ca2+) together with inorganic phosphate anions. Some so-called calcium phosphates contain oxide and hydroxide as well. Calcium phosphates are white solids of nutritional value[2] and are found in many living organisms, e.g., bone mineral and tooth enamel.[3] In milk, it exists in a colloidal form in micelles bound to casein protein with magnesium, zinc, and citrate–collectively referred to as colloidal calcium phosphate (CCP).[4] Various calcium phosphate minerals are used in the production of phosphoric acid and fertilizers. Overuse of certain forms of calcium phosphate can lead to nutrient-containing surface runoff and subsequent adverse effects upon receiving waters such as algal blooms and eutrophication (over-enrichment with nutrients and minerals).[citation needed]
Tricalcium phosphate (tribasic calcium phosphate or tricalcic phosphate, sometimes referred to as calcium phosphate or calcium orthophosphate, whitlockite), E341(iii) (CAS#7758-87-4): Ca3(PO4)2
Calcium phosphate stones account for approximately 15% of kidney stone disease. Calcium phosphate stones tend to grow in alkaline urine, especially when Proteus bacteria are present. It is the most common type in pregnant women.[5]
Calcium phosphate is the usual constitution of microcalcifications of the breast, particularly dystrophic calcifications. Microcalcifications as can be seen on mammography can be an early sign of breast cancer. Based on morphology, it is possible to classify by radiography how likely microcalcifications are to indicate cancer. [6]
Urine crystals comparison, with calcium phosphate crystal depicted at top center.
Histopathology of dystrophic calcium phosphate microcalcifications in ductal carcinoma in situ (DCIS) of the breast, H&E stain.
^Klaus Schrödter; Gerhard Bettermann; Thomas Staffel; Friedrich Wahl; Thomas Klein; Thomas Hofmann (2008). "Phosphoric Acid and Phosphates". Ullmann's Encyclopedia of Industrial Chemistry. Ullmann’s Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a19_465.pub3. ISBN978-3527306732. S2CID 94458523.
^"What Substances Make Up Your Teeth? – Affordable Dental Care". www.towncaredental.com. 2015-07-15. Retrieved 2021-01-29.
^A. Y. Tamime, ed. (2006). Brined cheeses - The Society of Dairy Technology (SDT). Wiley-Blackwell. ISBN978-1-4051-2460-7.
^Frassetto L, Kohlstadt I (2011). "Treatment and prevention of kidney stones: an update". Am Fam Physician. 84 (11): 1234–42. PMID 22150656.
^Nalawade, Yojana V (November 2009). "Evaluation of breast calcifications". The Indian Journal of Radiology & Imaging. 19 (4): 282–286. doi:10.4103/0971-3026.57208. ISSN 0971-3026. PMC2797739. PMID 19881103.
February 15, 2024
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For the function of calcium phosphate in organisms see Calcium metabolism This article needs additional citations for verification Please help improve this article by adding citations to reliable sources Unsourced material may be challenged and removed Find sources Calcium phosphate news newspapers books scholar JSTOR March 2019 Learn how and when to remove this template message The term calcium phosphate refers to a family of materials and minerals containing calcium ions Ca2 together with inorganic phosphate anions Some so called calcium phosphates contain oxide and hydroxide as well Calcium phosphates are white solids of nutritional value 2 and are found in many living organisms e g bone mineral and tooth enamel 3 In milk it exists in a colloidal form in micelles bound to casein protein with magnesium zinc and citrate collectively referred to as colloidal calcium phosphate CCP 4 Various calcium phosphate minerals are used in the production of phosphoric acid and fertilizers Overuse of certain forms of calcium phosphate can lead to nutrient containing surface runoff and subsequent adverse effects upon receiving waters such as algal blooms and eutrophication over enrichment with nutrients and minerals citation needed Calcium phosphate Calcium Phosphate nanowires seen in SEMIdentifiersCAS Number 7758 87 4EC Number 233 283 6E number E341 antioxidants PubChem CID 24456UNII K4C08XP666InChI Key QORWJWZARLRLPR UHFFFAOYSA HPropertiesChemical formula Ca3 PO4 2Molar mass 310 18 g molAppearance White SolidOdor OdorlessDensity 3 14 g cu cm 1 Melting point 1 670 C 3 040 F 1 940 K 1 Solubility in water Practically insoluble with waterSolubility in Ethanol Insoluble with ethanol also acetic acid HazardsGHS labelling PictogramsSignal word WarningHazard statements H315 H319 H335Precautionary statements P101 P102 P103 P261 P264 P270 P271 P280 P302 P352 P304 P340 P305 P351 P338NFPA 704 fire diamond 201Flash point Non flammableSafety data sheet SDS fishersci comExcept where otherwise noted data are given for materials in their standard state at 25 C 77 F 100 kPa Infobox references Contents 1 Orthophosphates di and monohydrogen phosphates 2 Di and polyphosphates 3 Hydroxy and oxo phosphates 4 Clinical significance 5 ReferencesOrthophosphates di and monohydrogen phosphates editThese materials contain Ca2 combined with PO3 4 HPO2 4 or H2 PO 4 Monocalcium phosphate E341 CAS 7758 23 8 for anhydrous CAS 10031 30 8 for monohydrate Ca H2PO4 2 and Ca H2PO4 2 H2O Dicalcium phosphate dibasic calcium phosphate E341 ii CAS 7757 93 9 CaHPO4 mineral monetite dihydrate CaHPO4 H2O 2 mineral brushite and monohydrate CaHPO4 H2O Tricalcium phosphate tribasic calcium phosphate or tricalcic phosphate sometimes referred to as calcium phosphate or calcium orthophosphate whitlockite E341 iii CAS 7758 87 4 Ca3 PO4 2 Octacalcium phosphate CAS 13767 12 9 Ca8H2 PO4 6 5H2O Amorphous calcium phosphate a glassy precipitate of variable composition that may be present in biological systems Di and polyphosphates editThese materials contain Ca2 combined with the polyphosphates such as P2 O4 7 and triphosphate P3 O5 10 Dicalcium diphosphate CAS 7790 76 3 Ca2P2O7 Calcium triphosphate CAS 26158 70 3 Ca5 P3O10 2Hydroxy and oxo phosphates editThese materials contain other anions in addition to phosphate citation needed Hydroxyapatite Ca5 PO4 3 OH Apatite Ca10 PO4 6 OH F Cl Br 2 Tetracalcium phosphate CAS 1306 01 0 Ca4 PO4 2OClinical significance editCalcium phosphate stones account for approximately 15 of kidney stone disease Calcium phosphate stones tend to grow in alkaline urine especially when Proteus bacteria are present It is the most common type in pregnant women 5 Calcium phosphate is the usual constitution of microcalcifications of the breast particularly dystrophic calcifications Microcalcifications as can be seen on mammography can be an early sign of breast cancer Based on morphology it is possible to classify by radiography how likely microcalcifications are to indicate cancer 6 nbsp Urine crystals comparison with calcium phosphate crystal depicted at top center nbsp Histopathology of dystrophic calcium phosphate microcalcifications in ductal carcinoma in situ DCIS of the breast H amp E stain References edit a b Calcium Phosphate Klaus Schrodter Gerhard Bettermann Thomas Staffel Friedrich Wahl Thomas Klein Thomas Hofmann 2008 Phosphoric Acid and Phosphates Ullmann s Encyclopedia of Industrial Chemistry Ullmann s Encyclopedia of Industrial Chemistry Weinheim Wiley VCH doi 10 1002 14356007 a19 465 pub3 ISBN 978 3527306732 S2CID 94458523 What Substances Make Up Your Teeth Affordable Dental Care www towncaredental com 2015 07 15 Retrieved 2021 01 29 A Y Tamime ed 2006 Brined cheeses The Society of Dairy Technology SDT Wiley Blackwell ISBN 978 1 4051 2460 7 Frassetto L Kohlstadt I 2011 Treatment and prevention of kidney stones an update Am Fam Physician 84 11 1234 42 PMID 22150656 Nalawade Yojana V November 2009 Evaluation of breast calcifications The Indian Journal of Radiology amp Imaging 19 4 282 286 doi 10 4103 0971 3026 57208 ISSN 0971 3026 PMC 2797739 PMID 19881103 Retrieved from https en wikipedia org w index php title Calcium phosphate amp oldid 1188977373, wikipedia, wiki, book, books, library,
