Aristolochia clematitis, the (European) birthwort, is a twining herbaceous plant in the family Aristolochiaceae, which is native to Europe. The leaves are heart shaped and the flowers are pale yellow and tubular in form. The plant seeks light by ascending the stems of surrounding plants.
It was formerly used as a medicinal plant, though it is poisonous, and is now occasionally found established outside of its native range as a relic of cultivation. It is now thought to be the cause of thousands of kidney failures in Romania, Bulgaria, Serbia, Bosnia and Herzegovina and Croatia. The initial hypothesis that seeds from the plant were unintentionally consumed through contaminated flour has come to be questioned.[1][2] Urinary tract malignancies among those who have consumed the plant are also reported.[3] The link between kidney failure and aristolochic acid, which the plant contains, was discovered after a clinic for obesity in Belgium used herbal products based on another plant of the same genus as a diuretic. After a few months, some of the patients experienced kidney failure.[4]
Wikimedia Commons has media related to Aristolochia clematitis.
^Grollman, A. P.; Shibutani, S.; Moriya, M.; Miller, F.; Wu, L.; Moll, U.; Suzuki, N.; Fernandes, A.; Rosenquist, T.; Medverec, Z.; Jakovina, K.; Brdar, B.; Slade, N.; Turesky, R. J.; Goodenough, A. K.; Rieger, R.; Vukelic, M.; Jelakovic, B. (2007). "Aristolochic acid and the etiology of endemic (Balkan) nephropathy". Proceedings of the National Academy of Sciences. 104 (29): 12129–34. Bibcode:2007PNAS..10412129G. doi:10.1073/pnas.0701248104. PMC1913550. PMID 17620607.
^Batuman, Elif. "Poisoned Land." The New Yorker. August 12 & 19, 2013: 42-47. Print.
^Broe, M. E. D. (2012). "Chinese herbs nephropathy and Balkan endemic nephropathy: Toward a single entity, aristolochic acid nephropathy". Kidney International. 81 (6): 513–515. doi:10.1038/ki.2011.428. PMID 22373701.
^Vanherweghem, J. L.; Tielemans, C.; Abramowicz, D.; Depierreux, M.; Vanhaelen-Fastre, R.; Vanhaelen, M.; Dratwa, M.; Richard, C.; Vandervelde, D.; Verbeelen, D.; Jadoul, M. (1993). "Rapidly progressive interstitial renal fibrosis in young women: Association with slimming regimen including Chinese herbs". The Lancet. 341 (8842): 387–91. doi:10.1016/0140-6736(93)92984-2. PMID 8094166. S2CID 32428737.
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aristolochia, clematitis, european, birthwort, twining, herbaceous, plant, family, aristolochiaceae, which, native, europe, leaves, heart, shaped, flowers, pale, yellow, tubular, form, plant, seeks, light, ascending, stems, surrounding, plants, scientific, cla. Aristolochia clematitis the European birthwort is a twining herbaceous plant in the family Aristolochiaceae which is native to Europe The leaves are heart shaped and the flowers are pale yellow and tubular in form The plant seeks light by ascending the stems of surrounding plants Aristolochia clematitisScientific classificationKingdom PlantaeClade TracheophytesClade AngiospermsClade MagnoliidsOrder PiperalesFamily AristolochiaceaeGenus AristolochiaSpecies A clematitisBinomial nameAristolochia clematitisL Aristolochia clematitis MHNTToxicity editIt was formerly used as a medicinal plant though it is poisonous and is now occasionally found established outside of its native range as a relic of cultivation It is now thought to be the cause of thousands of kidney failures in Romania Bulgaria Serbia Bosnia and Herzegovina and Croatia The initial hypothesis that seeds from the plant were unintentionally consumed through contaminated flour has come to be questioned 1 2 Urinary tract malignancies among those who have consumed the plant are also reported 3 The link between kidney failure and aristolochic acid which the plant contains was discovered after a clinic for obesity in Belgium used herbal products based on another plant of the same genus as a diuretic After a few months some of the patients experienced kidney failure 4 See also editBalkan nephropathyReferences edit nbsp Wikimedia Commons has media related to Aristolochia clematitis Grollman A P Shibutani S Moriya M Miller F Wu L Moll U Suzuki N Fernandes A Rosenquist T Medverec Z Jakovina K Brdar B Slade N Turesky R J Goodenough A K Rieger R Vukelic M Jelakovic B 2007 Aristolochic acid and the etiology of endemic Balkan nephropathy Proceedings of the National Academy of Sciences 104 29 12129 34 Bibcode 2007PNAS 10412129G doi 10 1073 pnas 0701248104 PMC 1913550 PMID 17620607 Batuman Elif Poisoned Land The New Yorker August 12 amp 19 2013 42 47 Print Broe M E D 2012 Chinese herbs nephropathy and Balkan endemic nephropathy Toward a single entity aristolochic acid nephropathy Kidney International 81 6 513 515 doi 10 1038 ki 2011 428 PMID 22373701 Vanherweghem J L Tielemans C Abramowicz D Depierreux M Vanhaelen Fastre R Vanhaelen M Dratwa M Richard C Vandervelde D Verbeelen D Jadoul M 1993 Rapidly progressive interstitial renal fibrosis in young women Association with slimming regimen including Chinese herbs The Lancet 341 8842 387 91 doi 10 1016 0140 6736 93 92984 2 PMID 8094166 S2CID 32428737 nbsp This Medicinal plants related article is a stub You can help Wikipedia by expanding it vte nbsp This Piperales related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Aristolochia clematitis amp oldid 1192153381, wikipedia, wiki, book, books, library,
