Annette G. Beck-Sickinger studied chemistry (diploma in 1986) and biology (diploma in 1990) at the University of Tübingen (Germany) and received her Ph.D. under the supervision of Günther Jung (Organic Chemistry, University of Tübingen).
Since October 1999, she is a full professor of Biochemistry and Bioorganic Chemistry at the University of Leipzig. In 2009, she spent a sabbatical at Vanderbilt University (Nashville, TN) as visiting professor.
Annette Beck-Sickinger was a member of the Board of the German Chemical Society (Gesellschaft Deutscher Chemiker, 2004-2012; Vice-President 2006-2008) and of the DFG panel "Biochemistry" (2004-2012). Since 2017, she is a member of the Board of the German Society for Biochemistry and Molecular Biology (gbm) and Vice-President. She was a member of the German Council of Science and Humanities (Wissenschaftsrat) from 2012-2018, and has been awarded with many prizes including the Leonidas Zervas Award of the European Peptide Society, the gold medal of the Max-Bergmann-Kreis, the Leipzig Science Award (2016) and the Albrecht Kossel Price of the German Chemical Society (2018). She was honoured with the membership of the Saxonian Academy of Science in 2009 and in 2012 became an elected member of the German National Academy of Sciences Leopoldina. In 2017, she was awarded with the Saxonian Order of Merit.[citation needed]
In March 2015, Beck-Sickinger was at the center of a controversy related to comments made during correspondence with an internship applicant in which she stated she would not accept any male students from India.[6][7][8][9]
The University declined to publish e-mails between Prof. Dr. Annette Beck-Sickinger and the student from India. However, the rector of the university, Prof. Dr. Beate Schücking as well as the students council of the university had the opportunity to review all relevant e-mails. Two independent statements have been published claiming that the mail published by the Indian student was faked as it only contained parts of the email conversation and that the student was declined for formal reasons.[10][11]
Germany's ambassador to India wrote a letter condemning Beck-Sickinger and, stating: "Your oversimplifying and discriminating generalisation is an offence to women and men ardently committed to furthering women's empowerment in India; and is an offence to millions of law-abiding, tolerant, open-minded and hard-working Indians. Let's be clear: India is not a country of rapists," he wrote.[12][13] "I would encourage you to learn more about the diverse, dynamic and fascinating country and the many welcoming and open-minded people of India so that you could correct a simplistic image, which – in my opinion – is particularly unsuitable for a professor and teacher."[14][15][16][17][18]
Selected bibliographyedit
Booksedit
Beck-Sickinger, Annette; Weber, Peter J. A. (1999). Kombinatorische Methoden in Chemie und Biologie. Spektrum Verlag. ISBN3827401577.
Beck-Sickinger, Annette; Weber, Peter (2002). Combinatorial strategies in biology and chemistry. Chichester, England New York: Wiley. ISBN9780471497271.
Beck-Sickinger, Annette; Hahn, Ulrich (2002). Lehrbuch der Biochemie (Herausgabe der deutschen Übersetzung von Voet, Voet, Pratt; Principles in Biochemistry). Wiley. ISBN352730519X.
Beck-Sickinger, Annette; Bräse, Stefan (2007). Combinatorial chemistry on solid supports. Berlin New York: Springer. ISBN9783540725091.
Beck-Sickinger, Annette; Petzold, Matthias (2009). Paradigma Evolution. Stuttgart: Peter Lang Verlag. ISBN978-3631560822.
Journal articlesedit
Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang, R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG*, Buschauer A, Wu B*. Structural basis of ligand binding modes at the neuropeptide Y Y(1) receptor. Nature. 2018 Apr;556(7702):520-524.
Wanka L, Babilon S, Kaiser A, Mörl K, Beck-Sickinger AG. Different mode of arrestin-3 binding at the human Y(1) and Y(2) receptor. Cell Signal. 2018 Oct;50:58-71.
Kaiser A, Hempel C, Wanka L, Schubert M, Hamm HE, Beck-Sickinger AG. G Protein Preassembly Rescues Efficacy of W(6.48) Toggle Mutations in Neuropeptide Y(2) Receptor. Mol Pharmacol. 2018 Apr;93(4):387-401.
Lotze J, Wolf P, Reinhardt U, Seitz O, Mörl K, Beck-Sickinger AG. Time-Resolved Tracking of Separately Internalized Neuropeptide Y(2) Receptors by Two-Color Pulse-Chase. ACS Chem Biol. 2018 Mar 16;13(3):618-627.
Schubert M, Stichel J, Du Y, Tough IR, Sliwoski G, Meiler J, Cox HM, Weaver CD, Beck-Sickinger AG. Identification and Characterization of the First Selective Y(4) Receptor Positive Allosteric Modulator. J Med Chem. 2017 Sep 14;60(17):7605-7612.
Böhme D, Krieghoff J, Beck-Sickinger AG. Double Methotrexate-Modified Neuropeptide Y Analogues Express Increased Toxicity and Overcome Drug Resistance in Breast Cancer Cells. J Med Chem. 2016 Apr 14;59(7):3409-17.
Zernia S, Ott F, Bellmann-Sickert K, Frank R, Klenner M, Jahnke HG, Prager A, Abel B, Robitzki A, Beck-Sickinger AG. Peptide-Mediated Specific Immobilization of Catalytically Active Cytochrome P450 BM3 Variant. Bioconjug Chem. 2016 Apr 20;27(4):1090-7.
Pagel M, Hassert R, John T, Braun K, Wießler M, Abel B, Beck-Sickinger AG. Multifunctional Coating Improves Cell Adhesion on Titanium by using Cooperatively Acting Peptides. Angew Chem Int Ed Engl. 2016 Apr 4;55(15):4826-30.
Ahrens VM, Kostelnik KB, Rennert R, Böhme D, Kalkhof S, Kosel D, Weber L, von Bergen M, Beck-Sickinger AG. A cleavable cytolysin-neuropeptide Y bioconjugate enables specific drug delivery and demonstrates intracellular mode of action. J Control Release. 2015 Jul 10;209:170-8.
Kaiser A, Müller P, Zellmann T, Scheidt HA, Thomas L, Bosse M, Meier R, Meiler J, Huster D, Beck-Sickinger AG, Schmidt P. Unwinding of the C-Terminal Residues of Neuropeptide Y is critical for Y2 Receptor Binding and Activation. Angew Chem Int Ed Engl. 2015 Jun 15;54(25):7446-9.
Michel, MC; Beck-Sickinger, A; Cox, H; Doods, HN; Herzog, H; Larhammar, D; Quirion, R; Schwartz, T; Westfall, T (March 1998). "XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors". Pharmacological Reviews. 50 (1). American Society for Pharmacology and Experimental Therapeutics: 143–50. PMID 9549761.
Referencesedit
^"Profile: Annette G. Beck-Sickinger, Prof. Dr. rer. nat. habil". Sächsische Akademie der Wissenschaften zu Leipzig.
^"Prof. Dr. Annette Beck-Sickinger". University of Leipzig. Retrieved 16 March 2015.
^Beck-Sickinger, Annette; Soderman, Peter Weber (2002). Combinatorial strategies in biology and chemistry. Translated by Michael Weir Allan. Chichester: John Wiley. ISBN0471497274.
^Michel, MC; Beck-Sickinger, A; Cox, H; Doods, HN; Herzog, H; Larhammar, D; Quirion, R; Schwartz, T; Westfall, T (March 1998). "XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors". Pharmacological Reviews. 50 (1). American Society for Pharmacology and Experimental Therapeutics: 143–50. PMID 9549761.
^Mascherin, Von Claudia (9 March 2015). "Keine Inder - das sind Vergewaltiger!". Blick (in German). Ringier. Retrieved 22 March 2015.
^Varghese, Johnlee (9 March 2015). "German professor apologises for denying internship to Indian student, citing 'rape problem'". International Business Times. Retrieved 22 March 2015.
^Phillip, Abby (9 March 2015). "German professor cites India's 'rape problem' in rejection of Indian applicant". The Washington Post. Retrieved 22 March 2015.
^Wendling, Mike (11 March 2015). "Second student allegedly rejected because of India's 'rape problem'". BBC Trending. Retrieved 22 March 2015.
^Universität Leipzig. . Archived from the original on June 12, 2015. Retrieved July 21, 2015.
^. StuRa Leipzig. Archived from the original on June 12, 2015. Retrieved July 21, 2015.
^"Second student allegedly rejected because of India's 'rape problem'". BBC News. 11 March 2015.
^"Professor apologizes for India rape comments". 10 March 2015.
^India is not a country of rapists: German envoy to discriminating German professor (The Hindu)
annette, beck, sickinger, annette, gabriele, beck, sickinger, born, october, 1960, german, chemist, biologist, been, full, professor, biochemistry, bioorganic, chemistry, university, leipzig, since, 1999, annette, gabriele, beck, sickingerbornannette, gabriele. Annette Gabriele Beck Sickinger born 28 October 1960 1 is a German chemist and biologist She has been a full professor of Biochemistry and Bioorganic Chemistry at the University of Leipzig since 1999 Annette Gabriele Beck SickingerBornAnnette Gabriele Beck Sickinger 1960 10 28 28 October 1960 age 63 NationalityGermanAlma materUniversity of TubingenKnown forGPCR research peptide hormones peptide and protein modificationScientific careerInstitutionsUniversity of LeipzigWebsitewww wbr saw leipzig wbr de wbr de wbr mitglieder wbr beckabiochemie wbr biphaps wbr uni leipzig wbr de wbr en wbr groups wbr biochemistry and bioorganic chemistry wbr Contents 1 Career 2 Controversy 3 Selected bibliography 3 1 Books 3 2 Journal articles 4 References 5 External linksCareer editAnnette G Beck Sickinger studied chemistry diploma in 1986 and biology diploma in 1990 at the University of Tubingen Germany and received her Ph D under the supervision of Gunther Jung Organic Chemistry University of Tubingen Since October 1999 she is a full professor of Biochemistry and Bioorganic Chemistry at the University of Leipzig In 2009 she spent a sabbatical at Vanderbilt University Nashville TN as visiting professor Annette Beck Sickinger was a member of the Board of the German Chemical Society Gesellschaft Deutscher Chemiker 2004 2012 Vice President 2006 2008 and of the DFG panel Biochemistry 2004 2012 Since 2017 she is a member of the Board of the German Society for Biochemistry and Molecular Biology gbm and Vice President She was a member of the German Council of Science and Humanities Wissenschaftsrat from 2012 2018 and has been awarded with many prizes including the Leonidas Zervas Award of the European Peptide Society the gold medal of the Max Bergmann Kreis the Leipzig Science Award 2016 and the Albrecht Kossel Price of the German Chemical Society 2018 She was honoured with the membership of the Saxonian Academy of Science in 2009 and in 2012 became an elected member of the German National Academy of Sciences Leopoldina In 2017 she was awarded with the Saxonian Order of Merit citation needed She is a member of the German Chemical Society the Saxonian Academy of Sciences 2 and the German Academy of Sciences Leopoldina 3 She is known for her work on peptide signaling she has coauthored reference works on combinatorial chemistry as applied to peptides 4 and has participated in International Union of Pharmacology projects on standardization of nomenclature for G protein coupled receptor peptide ligands 5 Controversy editMain article Leipzig University internship controversy In March 2015 Beck Sickinger was at the center of a controversy related to comments made during correspondence with an internship applicant in which she stated she would not accept any male students from India 6 7 8 9 The University declined to publish e mails between Prof Dr Annette Beck Sickinger and the student from India However the rector of the university Prof Dr Beate Schucking as well as the students council of the university had the opportunity to review all relevant e mails Two independent statements have been published claiming that the mail published by the Indian student was faked as it only contained parts of the email conversation and that the student was declined for formal reasons 10 11 Germany s ambassador to India wrote a letter condemning Beck Sickinger and stating Your oversimplifying and discriminating generalisation is an offence to women and men ardently committed to furthering women s empowerment in India and is an offence to millions of law abiding tolerant open minded and hard working Indians Let s be clear India is not a country of rapists he wrote 12 13 I would encourage you to learn more about the diverse dynamic and fascinating country and the many welcoming and open minded people of India so that you could correct a simplistic image which in my opinion is particularly unsuitable for a professor and teacher 14 15 16 17 18 Selected bibliography editBooks edit Beck Sickinger Annette Weber Peter J A 1999 Kombinatorische Methoden in Chemie und Biologie Spektrum Verlag ISBN 3827401577 Beck Sickinger Annette Weber Peter 2002 Combinatorial strategies in biology and chemistry Chichester England New York Wiley ISBN 9780471497271 Beck Sickinger Annette Hahn Ulrich 2002 Lehrbuch der Biochemie Herausgabe der deutschen Ubersetzung von Voet Voet Pratt Principles in Biochemistry Wiley ISBN 352730519X Beck Sickinger Annette Brase Stefan 2007 Combinatorial chemistry on solid supports Berlin New York Springer ISBN 9783540725091 Beck Sickinger Annette Petzold Matthias 2009 Paradigma Evolution Stuttgart Peter Lang Verlag ISBN 978 3631560822 Journal articles edit Yang Z Han S Keller M Kaiser A Bender BJ Bosse M Burkert K Kogler LM Wifling D Bernhardt G Plank N Littmann T Schmidt P Yi C Li B Ye S Zhang R Xu B Larhammar D Stevens RC Huster D Meiler J Zhao Q Beck Sickinger AG Buschauer A Wu B Structural basis of ligand binding modes at the neuropeptide Y Y 1 receptor Nature 2018 Apr 556 7702 520 524 Wanka L Babilon S Kaiser A Morl K Beck Sickinger AG Different mode of arrestin 3 binding at the human Y 1 and Y 2 receptor Cell Signal 2018 Oct 50 58 71 Kaiser A Hempel C Wanka L Schubert M Hamm HE Beck Sickinger AG G Protein Preassembly Rescues Efficacy of W 6 48 Toggle Mutations in Neuropeptide Y 2 Receptor Mol Pharmacol 2018 Apr 93 4 387 401 Lotze J Wolf P Reinhardt U Seitz O Morl K Beck Sickinger AG Time Resolved Tracking of Separately Internalized Neuropeptide Y 2 Receptors by Two Color Pulse Chase ACS Chem Biol 2018 Mar 16 13 3 618 627 Schubert M Stichel J Du Y Tough IR Sliwoski G Meiler J Cox HM Weaver CD Beck Sickinger AG Identification and Characterization of the First Selective Y 4 Receptor Positive Allosteric Modulator J Med Chem 2017 Sep 14 60 17 7605 7612 Bohme D Krieghoff J Beck Sickinger AG Double Methotrexate Modified Neuropeptide Y Analogues Express Increased Toxicity and Overcome Drug Resistance in Breast Cancer Cells J Med Chem 2016 Apr 14 59 7 3409 17 Zernia S Ott F Bellmann Sickert K Frank R Klenner M Jahnke HG Prager A Abel B Robitzki A Beck Sickinger AG Peptide Mediated Specific Immobilization of Catalytically Active Cytochrome P450 BM3 Variant Bioconjug Chem 2016 Apr 20 27 4 1090 7 Pagel M Hassert R John T Braun K Wiessler M Abel B Beck Sickinger AG Multifunctional Coating Improves Cell Adhesion on Titanium by using Cooperatively Acting Peptides Angew Chem Int Ed Engl 2016 Apr 4 55 15 4826 30 Ahrens VM Kostelnik KB Rennert R Bohme D Kalkhof S Kosel D Weber L von Bergen M Beck Sickinger AG A cleavable cytolysin neuropeptide Y bioconjugate enables specific drug delivery and demonstrates intracellular mode of action J Control Release 2015 Jul 10 209 170 8 Kaiser A Muller P Zellmann T Scheidt HA Thomas L Bosse M Meier R Meiler J Huster D Beck Sickinger AG Schmidt P Unwinding of the C Terminal Residues of Neuropeptide Y is critical for Y2 Receptor Binding and Activation Angew Chem Int Ed Engl 2015 Jun 15 54 25 7446 9 Michel MC Beck Sickinger A Cox H Doods HN Herzog H Larhammar D Quirion R Schwartz T Westfall T March 1998 XVI International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y peptide YY and pancreatic polypeptide receptors Pharmacological Reviews 50 1 American Society for Pharmacology and Experimental Therapeutics 143 50 PMID 9549761 References edit Profile Annette G Beck Sickinger Prof Dr rer nat habil Sachsische Akademie der Wissenschaften zu Leipzig Prof Dr Annette Beck Sickinger University of Leipzig Retrieved 16 March 2015 List of members Prof Dr Annette G Beck Sickinger Leopoldina Nationale Akademie der Wissenschaften Beck Sickinger Annette Soderman Peter Weber 2002 Combinatorial strategies in biology and chemistry Translated by Michael Weir Allan Chichester John Wiley ISBN 0471497274 Michel MC Beck Sickinger A Cox H Doods HN Herzog H Larhammar D Quirion R Schwartz T Westfall T March 1998 XVI International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y peptide YY and pancreatic polypeptide receptors Pharmacological Reviews 50 1 American Society for Pharmacology and Experimental Therapeutics 143 50 PMID 9549761 Mascherin Von Claudia 9 March 2015 Keine Inder das sind Vergewaltiger Blick in German Ringier Retrieved 22 March 2015 Varghese Johnlee 9 March 2015 German professor apologises for denying internship to Indian student citing rape problem International Business Times Retrieved 22 March 2015 Phillip Abby 9 March 2015 German professor cites India s rape problem in rejection of Indian applicant The Washington Post Retrieved 22 March 2015 Wendling Mike 11 March 2015 Second student allegedly rejected because of India s rape problem BBC Trending Retrieved 22 March 2015 Universitat Leipzig Universitat Leipzig Nachrichten Archived from the original on June 12 2015 Retrieved July 21 2015 Statement in der Causa Beck Sickinger StuRa Leipzig Archived from the original on June 12 2015 Retrieved July 21 2015 Second student allegedly rejected because of India s rape problem BBC News 11 March 2015 Professor apologizes for India rape comments 10 March 2015 India is not a country of rapists German envoy to discriminating German professor The Hindu Prof rejects Indian intern over rape problem German Professor Apologises for Denying Internship to Indian Student Citing Rape Problem India Business Times German professor denies internship to Indian student citing India s rape problem Deccan Chronicle German professor apologises for rejecting internship to student citing India s rape problem Hindustan Times External links editProfile Annette Beck Sickinger University of Leipzig Portals nbsp Biography nbsp Science nbsp Biology nbsp Chemistry nbsp Germany Retrieved from https en wikipedia org w index php title Annette Beck Sickinger amp oldid 1173220328, wikipedia, wiki, book, books, library,
