Angiokeratoma is a benign cutaneous lesion of capillaries, resulting in small marks of red to blue color and characterized by hyperkeratosis. Angiokeratoma corporis diffusum refers to Fabry's disease,[1] but this is usually considered a distinct condition.
Multiple angiokeratomas, especially on the trunk in young people, are typical for Fabry disease, genetic disorder connected with systemic complications.
Complicationsedit
In some instances nodular angiokeratomas can produce necrotic tissue and valleys that can harbor fungal, bacterial and viral infections. Infections can include staphylococcus. If the lesion becomes painful, begins draining fluids or pus, or begins to smell, consult a physician. In these instance a doctor may recommend excision and grafting.
Pathophysiologyedit
Histologyedit
Angiokeratomas characteristically have large dilated blood vessels in the superficial dermis and hyperkeratosis (overlying the dilated vessels).
Scrotal angiokeratoma; visible large dilated blood vessels and hyperkeratosis
Scrotal angiokeratoma (Fordyce type); multiple papules made by dilatated capillaries
Scrotal angiokeratoma (Mibelli type); blood vessels close to the epidermis
Angiokeratoma (Mibelli type)
Diagnosisedit
Due to the rarity of different types of vascular conditions, angiokeratomas may be misdiagnosed. A biopsy of the lesion can produce a more accurate diagnosis.[citation needed]
Classificationedit
Angiokeratoma may be classified as:
Angiokeratoma of Mibelli (also known as "Mibelli's angiokeratoma,"[4] "Telangiectatic warts"[5]) consists of 1- to 5-mm red vascular papules, the surfaces of which become hyperkeratotic in the course of time.[5]: 589 The disease is named after Italian dermatologistVittorio Mibelli (1860-1910).[6]
Angiokeratoma of Fordyce (also known as "Angiokeratoma of the scrotum and vulva," though not to be confused with Fordyce's spots)[5] is a skin condition characterized by red to blue papules on the scrotum or vulva.
Solitary angiokeratoma is a small, bluish-black, warty papule that occurs predominantly on the lower extremities.[5]: 590
Verrucous vascular malformation (also known as "Angiokeratoma circumscriptum naeviforme") is a malformation of dermal and subcutaneous capillaries and veins, a congenital vascular malformation, which, over time, a verrucous component appears.[5]: 584
Treatmentedit
Outpatient treatments such as interventional radiology, lasers, and physical therapy are employed to reduce the severity of the vascular lesions. However, in some cases lasers have caused a reaction in the tissue causing it to expand and become exposed to infection. Excision and grafting may be necessary to remove the lesion. Recovery time on such an operation ranges from 3 to 12 weeks depending on location of the graft, healing time and the possibility of complications.[citation needed]
^Trickett R, Dowd H (October 2006). "Angiokeratoma of the scrotum: a case of scrotal bleeding". Emerg Med J. 23 (10): e57. doi:10.1136/emj.2006.038745. PMC2579622. PMID 16988295.
^Sion-Vardy N, Manor E, Puterman M, Bodner L (January 2008). "Solitary angiokeratoma of the tongue" (PDF). Med Oral Patol Oral Cir Bucal. 13 (1): E12–4. PMID 18167473.
^Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN978-1-4160-2999-1.
^ abcdeJames, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN0-7216-2921-0.
angiokeratoma, benign, cutaneous, lesion, capillaries, resulting, small, marks, blue, color, characterized, hyperkeratosis, corporis, diffusum, refers, fabry, disease, this, usually, considered, distinct, condition, specialtyoncology, dermatology, contents, si. Angiokeratoma is a benign cutaneous lesion of capillaries resulting in small marks of red to blue color and characterized by hyperkeratosis Angiokeratoma corporis diffusum refers to Fabry s disease 1 but this is usually considered a distinct condition AngiokeratomaSpecialtyOncology dermatology Contents 1 Signs and symptoms 1 1 Complications 2 Pathophysiology 2 1 Histology 3 Diagnosis 3 1 Classification 4 Treatment 5 See also 6 References 7 External linksSigns and symptoms editPresentation includes telangiectasia acanthosis and hyperkeratosis 2 Presentation can be solitary or systemic 3 Multiple angiokeratomas especially on the trunk in young people are typical for Fabry disease genetic disorder connected with systemic complications Complications edit In some instances nodular angiokeratomas can produce necrotic tissue and valleys that can harbor fungal bacterial and viral infections Infections can include staphylococcus If the lesion becomes painful begins draining fluids or pus or begins to smell consult a physician In these instance a doctor may recommend excision and grafting Pathophysiology editHistology edit Angiokeratomas characteristically have large dilated blood vessels in the superficial dermis and hyperkeratosis overlying the dilated vessels nbsp Scrotal angiokeratoma visible large dilated blood vessels and hyperkeratosis nbsp Scrotal angiokeratoma Fordyce type multiple papules made by dilatated capillaries nbsp Scrotal angiokeratoma Fordyce type dilated cavernous capillaries acanthosis nbsp Scrotal angiokeratoma Mibelli type blood vessels close to the epidermis nbsp Angiokeratoma Mibelli type Diagnosis editDue to the rarity of different types of vascular conditions angiokeratomas may be misdiagnosed A biopsy of the lesion can produce a more accurate diagnosis citation needed Classification edit Angiokeratoma may be classified as Angiokeratoma of Mibelli also known as Mibelli s angiokeratoma 4 Telangiectatic warts 5 consists of 1 to 5 mm red vascular papules the surfaces of which become hyperkeratotic in the course of time 5 589 The disease is named after Italian dermatologist Vittorio Mibelli 1860 1910 6 Angiokeratoma of Fordyce also known as Angiokeratoma of the scrotum and vulva though not to be confused with Fordyce s spots 5 is a skin condition characterized by red to blue papules on the scrotum or vulva Solitary angiokeratoma is a small bluish black warty papule that occurs predominantly on the lower extremities 5 590 Verrucous vascular malformation also known as Angiokeratoma circumscriptum naeviforme is a malformation of dermal and subcutaneous capillaries and veins a congenital vascular malformation which over time a verrucous component appears 5 584 Treatment editOutpatient treatments such as interventional radiology lasers and physical therapy are employed to reduce the severity of the vascular lesions However in some cases lasers have caused a reaction in the tissue causing it to expand and become exposed to infection Excision and grafting may be necessary to remove the lesion Recovery time on such an operation ranges from 3 to 12 weeks depending on location of the graft healing time and the possibility of complications citation needed See also editFabry disease List of cutaneous conditionsReferences edit Trickett R Dowd H October 2006 Angiokeratoma of the scrotum a case of scrotal bleeding Emerg Med J 23 10 e57 doi 10 1136 emj 2006 038745 PMC 2579622 PMID 16988295 angiokeratoma at Dorland s Medical Dictionary Sion Vardy N Manor E Puterman M Bodner L January 2008 Solitary angiokeratoma of the tongue PDF Med Oral Patol Oral Cir Bucal 13 1 E12 4 PMID 18167473 Rapini Ronald P Bolognia Jean L Jorizzo Joseph L 2007 Dermatology 2 Volume Set St Louis Mosby ISBN 978 1 4160 2999 1 a b c d e James William Berger Timothy Elston Dirk 2005 Andrews Diseases of the Skin Clinical Dermatology 10th ed Saunders ISBN 0 7216 2921 0 Mibelli s disease II Who Named ItExternal links edit Retrieved from https en wikipedia org w index php title Angiokeratoma amp oldid 1126339642, wikipedia, wiki, book, books, library,
