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Amparo Acker-Palmer (born 10 September 1968) is a German-based Spanish cell biologist and neuroscientist. Her research focuses on the similarities of the mechanism of nerve and blood vessel development.[1] She has worked alongside her husband, Till Acker, who is a neurobiologist, in researching tumor therapies.[2] In her career, she has won several awards, including the Paul Ehrlich & Ludwig Darmstaeder Prize for Young Researchers in 2010.[3] In 2012, Amparo Acker-Palmer was elected as member of the German Academy of Sciences Leopoldina.[4]
Originally from Sueca, Valencia, Spain, Acker-Palmer obtained a B.A. in biology and biochemistry in the University of Valencia in 1991.[5] After graduating, she completed a postdoctoral fellowship at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany in 1996 after obtaining a PhD in biology in the University of Valencia in the same year.[5]
In 2001, she moved to Martinsried to take the position as a junior group leader at the Max Planck Institute for Neurobiology for six years.[6] At Goethe University, she was nominated as Professor of Cluster of Excellence "Macromolecular Complexes" in 2007.[7]
In 2011, she became the head of the Department of Molecular and Cellular Neurobiology at Goethe University, while working on research in a specialised program known as the Focus Program Translational Neurosciences (FTN).[8] During this time she was a faculty member at the Johannes Gutenberg–University Mainz through her GFK Fellowship.[9] In 2014, she was then elected as a Max Planck Fellow at the Max Planck Institute for Brain Research, where she conducted research focused on the mechanics of nerve and blood vessel communication.[6]
Research
Acker-Palmer's work focused on the mechanism of the development of nerve and blood vessel at the molecular level. Alongside her colleagues, she published her work in Nature in 2010, as "EphrinB2 regulates VEGFR2 function in developmental and tumour angiogenesis". She won the Paul Ehrlich & Ludwig Darmstaeder Prize for Young Researchers for discovering the similarities between nerve and blood vessel development.[3]
Ephrin is one of the axon's guiding molecules during the development of the central nervous system. Her research examines the role of one of Ephrin's receptor'stransmembraneligand, Ephrin-B2 in particular, in developmental angiogenesis.[10] However, the validity of the study's data was placed under scrutiny by Nature's readership due to its questionable figures.[11]
To clarify the situation, a letter along with supplementary information was issued by the authors explaining the errors made. According to Nature, although several images were incorrectly labelled, the errors have no effect on the experiment's original conclusion. The authors have also conducted another experiment for further verification, which confirmed their results.[12]
Honours and awards
Received a Doctoral Fellowship from the Spanish Government (1992–1996)[9]
Received a Doctoral Extraordinary Award from the University of Valencia, Spain (1997)[5]
Elected as the EU Fellow in the "Training and Mobility of Researchers Programme" (1997–1999)[13]
Won €60,000 from the Paul Ehrlich & Ludwig Darmstaeder Prize for Young Researchers for her research in discovering the similarities between nerve and blood vessel development (2010)[3]
Received the Gutenberg Research Fellowship Award (2012)[9]
Elected as a Max Planck Fellow at the MPI for Brain Research (2014)[6]
Received a €2.5 million award from the European Research Council (ERC) (2015)[14]
Selected publications
Senturk, A; Pfennig, S .; Weiss, A .; Burk, K. (2011). "EphrinBs are functional co-receptors for Reelin to regulate neuronal migration." Nature (in English) (Band 472): 356–360. doi:10.1038/nature09874.
Sawamiphak, S .; Seidel, S .; Essmann, CL; Wilkinson, G .; Pitulescu, ME; Acker, T. (2010). 'EphrinB2 regulates VEGFR2 function in developmental and tumor angiogenesis'. Nature (in English) (Band 465): 487–491. doi: 10.1038/nature08995.
Sawamiphak, S .; Ritter, M. (2008). "Preparation of retinal cultures to study ex vivo tip endothelial cell responses". Nature Protocols ( Band 5 edition): 1659–1665. doi:10.1038/nprot.2010.130.
Essmann, CL; Martinez, E .; Geiger, J .; Zimmer, M .; Traut, M .; Stein, V .; Klein, R. (2008). 'Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors'. Nature Neuroscience ( Band 11): 105–1043. doi:10.1038/nn.2171.
Segura, I .; Essmann, CL; Weinges, S. (2007). "Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation". Nature Neuroscience ( Band 10): 301–310. doi:10.1038/nn1858.
^Beeger, Britta; Siedenbiedel, Christian (24 August 2013). "Amparo Acker-Palmer: Exzellente Fachfrau für Zellen". Frankfurter Allgemeine Zeitung (in German). ISSN 0174-4909. Retrieved 18 April 2017.
^"New target for tumor therapy - Nature letter: When drugs could permanently disrupt the pathological formation of blood vessels". www.bmls.de. Retrieved 18 April 2017.
^ abc"Frankfurt scientist Prof. Amparo Acker-Palmer awarded the 2010 Prize for Young Researchers" (PDF). Goethe Universitat Frankfurt Am Main.
^. Archived from the original on 7 August 2018. Retrieved 7 August 2018.
^ abcMCNB. "Biography of Prof. Dr. Amparo Acker-Palmer". neuro-vessel-frankfurt.de. Retrieved 18 April 2017.
^ abc. www.muk.uni-frankfurt.de. Archived from the original on 19 April 2017. Retrieved 18 April 2017.
^. www.muk.uni-frankfurt.de. Archived from the original on 22 April 2017. Retrieved 18 April 2017.
^Mainz, Johannes Gutenberg-Universität. "Herzlich willkommen beim Forschungszentrum Translationale Neurowissenschaften (FTN)". www.ftn.uni-mainz.de (in German). Retrieved 5 December 2017.
^ abcMainz, Johannes Gutenberg-Universität. "Amparo Acker-Palmer zum GFK-Fellow ernannt". www.uni-mainz.de (in German). Retrieved 18 April 2017.
^Sawamiphak, Suphansa; Seidel, Sascha; Essmann, Clara L.; Wilkinson, George A.; Pitulescu, Mara E.; Acker, Till; Acker-Palmer, Amparo (27 May 2010). "Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis". Nature. 465 (7297): 487–491. Bibcode:2010Natur.465..487S. doi:10.1038/nature08995. ISSN 0028-0836. PMID 20445540. S2CID 4423684.
^"You can do that? A massive correction in Nature, but no retraction". Retraction Watch. 28 September 2011. Retrieved 18 April 2017.
^Sentürk, Aycan; Pfennig, Sylvia; Weiss, Alexander; Burk, Katja; Acker-Palmer, Amparo (13 October 2011). "Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration". Nature. 478 (7368): 274. Bibcode:2011Natur.478..274S. doi:10.1038/nature10420. ISSN 0028-0836.
^"Prof. Dr. Amparo Acker-Palmer - AcademiaNet". www.academia-net.org. Retrieved 18 April 2017.
^"Prestigious awards for former Research Group Leaders". www.neuro.mpg.de. Retrieved 19 April 2017.
February 27, 2023
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This article is an orphan as no other articles link to it Please introduce links to this page from related articles try the Find link tool for suggestions April 2017 Amparo Acker Palmer born 10 September 1968 is a German based Spanish cell biologist and neuroscientist Her research focuses on the similarities of the mechanism of nerve and blood vessel development 1 She has worked alongside her husband Till Acker who is a neurobiologist in researching tumor therapies 2 In her career she has won several awards including the Paul Ehrlich amp Ludwig Darmstaeder Prize for Young Researchers in 2010 3 In 2012 Amparo Acker Palmer was elected as member of the German Academy of Sciences Leopoldina 4 Amparo Acker PalmerBorn10 September 1968Sueca SpainNationalitySpanishAlma materUniversity of ValenciaOccupationsscientistcell biologistneuroscientistEmployerGoethe University Frankfurt Rhine Main Neuroscience NetworkSpouseTill AckerChildren2AwardsThe Paul Ehrlich and Ludwig Darmstaedter Prize 2010 Contents 1 Education and career 2 Research 3 Honours and awards 4 Selected publications 5 See also 6 ReferencesEducation and career EditOriginally from Sueca Valencia Spain Acker Palmer obtained a B A in biology and biochemistry in the University of Valencia in 1991 5 After graduating she completed a postdoctoral fellowship at the European Molecular Biology Laboratory EMBL in Heidelberg Germany in 1996 after obtaining a PhD in biology in the University of Valencia in the same year 5 In 2001 she moved to Martinsried to take the position as a junior group leader at the Max Planck Institute for Neurobiology for six years 6 At Goethe University she was nominated as Professor of Cluster of Excellence Macromolecular Complexes in 2007 7 In 2011 she became the head of the Department of Molecular and Cellular Neurobiology at Goethe University while working on research in a specialised program known as the Focus Program Translational Neurosciences FTN 8 During this time she was a faculty member at the Johannes Gutenberg University Mainz through her GFK Fellowship 9 In 2014 she was then elected as a Max Planck Fellow at the Max Planck Institute for Brain Research where she conducted research focused on the mechanics of nerve and blood vessel communication 6 Research EditAcker Palmer s work focused on the mechanism of the development of nerve and blood vessel at the molecular level Alongside her colleagues she published her work in Nature in 2010 as EphrinB2 regulates VEGFR2 function in developmental and tumour angiogenesis She won the Paul Ehrlich amp Ludwig Darmstaeder Prize for Young Researchers for discovering the similarities between nerve and blood vessel development 3 Ephrin is one of the axon s guiding molecules during the development of the central nervous system Her research examines the role of one of Ephrin s receptor s transmembrane ligand Ephrin B2 in particular in developmental angiogenesis 10 However the validity of the study s data was placed under scrutiny by Nature s readership due to its questionable figures 11 To clarify the situation a letter along with supplementary information was issued by the authors explaining the errors made According to Nature although several images were incorrectly labelled the errors have no effect on the experiment s original conclusion The authors have also conducted another experiment for further verification which confirmed their results 12 Honours and awards EditReceived a Doctoral Fellowship from the Spanish Government 1992 1996 9 Received a Doctoral Extraordinary Award from the University of Valencia Spain 1997 5 Elected as the EU Fellow in the Training and Mobility of Researchers Programme 1997 1999 13 Won 60 000 from the Paul Ehrlich amp Ludwig Darmstaeder Prize for Young Researchers for her research in discovering the similarities between nerve and blood vessel development 2010 3 Received the Gutenberg Research Fellowship Award 2012 9 Elected as a Max Planck Fellow at the MPI for Brain Research 2014 6 Received a 2 5 million award from the European Research Council ERC 2015 14 Selected publications EditSenturk A Pfennig S Weiss A Burk K 2011 EphrinBs are functional co receptors for Reelin to regulate neuronal migration Nature in English Band 472 356 360 doi 10 1038 nature09874 Sawamiphak S Seidel S Essmann CL Wilkinson G Pitulescu ME Acker T 2010 EphrinB2 regulates VEGFR2 function in developmental and tumor angiogenesis Nature in English Band 465 487 491 doi 10 1038 nature08995 Sawamiphak S Ritter M 2008 Preparation of retinal cultures to study ex vivo tip endothelial cell responses Nature Protocols Band 5 edition 1659 1665 doi 10 1038 nprot 2010 130 Essmann CL Martinez E Geiger J Zimmer M Traut M Stein V Klein R 2008 Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors Nature Neuroscience Band 11 105 1043 doi 10 1038 nn 2171 Segura I Essmann CL Weinges S 2007 Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation Nature Neuroscience Band 10 301 310 doi 10 1038 nn1858 See also EditList of Spanish inventors and discoverersReferences Edit Beeger Britta Siedenbiedel Christian 24 August 2013 Amparo Acker Palmer Exzellente Fachfrau fur Zellen Frankfurter Allgemeine Zeitung in German ISSN 0174 4909 Retrieved 18 April 2017 New target for tumor therapy Nature letter When drugs could permanently disrupt the pathological formation of blood vessels www bmls de Retrieved 18 April 2017 a b c Frankfurt scientist Prof Amparo Acker Palmer awarded the 2010 Prize for Young Researchers PDF Goethe Universitat Frankfurt Am Main Mitgliederverzeichnis Archived from the original on 7 August 2018 Retrieved 7 August 2018 a b c MCNB Biography of Prof Dr Amparo Acker Palmer neuro vessel frankfurt de Retrieved 18 April 2017 a b c Goethe Universitat Wie sprechen Nervenzellen und Blutgefasse miteinander www muk uni frankfurt de Archived from the original on 19 April 2017 Retrieved 18 April 2017 Goethe Universitat Weitere Wurdigung fur Frankfurter Wissenschaftlerin www muk uni frankfurt de Archived from the original on 22 April 2017 Retrieved 18 April 2017 Mainz Johannes Gutenberg Universitat Herzlich willkommen beim Forschungszentrum Translationale Neurowissenschaften FTN www ftn uni mainz de in German Retrieved 5 December 2017 a b c Mainz Johannes Gutenberg Universitat Amparo Acker Palmer zum GFK Fellow ernannt www uni mainz de in German Retrieved 18 April 2017 Sawamiphak Suphansa Seidel Sascha Essmann Clara L Wilkinson George A Pitulescu Mara E Acker Till Acker Palmer Amparo 27 May 2010 Ephrin B2 regulates VEGFR2 function in developmental and tumour angiogenesis Nature 465 7297 487 491 Bibcode 2010Natur 465 487S doi 10 1038 nature08995 ISSN 0028 0836 PMID 20445540 S2CID 4423684 You can do that A massive correction in Nature but no retraction Retraction Watch 28 September 2011 Retrieved 18 April 2017 Senturk Aycan Pfennig Sylvia Weiss Alexander Burk Katja Acker Palmer Amparo 13 October 2011 Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration Nature 478 7368 274 Bibcode 2011Natur 478 274S doi 10 1038 nature10420 ISSN 0028 0836 Prof Dr Amparo Acker Palmer AcademiaNet www academia net org Retrieved 18 April 2017 Prestigious awards for former Research Group Leaders www neuro mpg de Retrieved 19 April 2017 Retrieved from https en wikipedia org w index php title Amparo Acker Palmer amp oldid 1106336268, wikipedia, wiki, book, books, library,
