5F-NNE1 (also known as 5F-NNEI and 5F-MN-24) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug.[1][2] Given the known metabolic liberation (and presence as an impurity) of amantadine in the related compound APINACA, it is suspected that metabolic hydrolysis of the amide group of 5F-NNE1 may release 1-naphthylamine, a known carcinogen.
^. Southern Association of Forensic Scientists. Archived from the original on 27 May 2015. Retrieved 24 July 2015.
^Wohlfarth A, Castaneto MS, Zhu M, Pang S, Scheidweiler KB, Kronstrand R, Huestis MA (May 2015). "Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA". The AAPS Journal. 17 (3): 660–77. doi:10.1208/s12248-015-9721-0. PMC4406957. PMID 25721194.
^"Cannabinoider föreslås bli klassade som hälsofarlig vara". Folkhälsomyndigheten. Retrieved 24 July 2015.
This cannabinoid related article is a stub. You can help Wikipedia by expanding it.
nne1, also, known, nnei, indole, based, synthetic, cannabinoid, that, presumed, potent, agonist, receptor, been, sold, online, designer, drug, given, known, metabolic, liberation, presence, impurity, amantadine, related, compound, apinaca, suspected, that, met. 5F NNE1 also known as 5F NNEI and 5F MN 24 is an indole based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug 1 2 Given the known metabolic liberation and presence as an impurity of amantadine in the related compound APINACA it is suspected that metabolic hydrolysis of the amide group of 5F NNE1 may release 1 naphthylamine a known carcinogen 5F NNE1Legal statusLegal statusCA Schedule II DE NpSG Industrial and scientific use only UK Class BIdentifiersIUPAC name 1 5 Fluoropentyl N naphthalen 1 yl 1H indole 3 carboxamideCAS Number1445580 60 8PubChem CID118796566ChemSpider29341632UNII3T22QDP4D9Chemical and physical dataFormulaC 24H 23F N 2OMolar mass374 459 g mol 13D model JSmol Interactive imageSMILES FCCCCCn1cc c2c1cccc2 C O Nc1cccc2c1cccc2InChI InChI 1S C24H23FN2O c25 15 6 1 7 16 27 17 21 20 12 4 5 14 23 20 27 24 28 26 22 13 8 10 18 9 2 3 11 19 18 22 h2 5 8 14 17H 1 6 7 15 16H2 H 26 28 Key DJKVOBZLMBHFKX UHFFFAOYSA NLegality editSweden s public health agency suggested classifying 5F NNE1 as hazardous substance on November 10 2014 3 See also edit5F ADBICA 5F SDB 006 AM 2201 FDU NNE1 FUB 144 MMB 2201 NNE1 PX 1References edit 5F NNEI Southern Association of Forensic Scientists Archived from the original on 27 May 2015 Retrieved 24 July 2015 Wohlfarth A Castaneto MS Zhu M Pang S Scheidweiler KB Kronstrand R Huestis MA May 2015 Pentylindole Pentylindazole Synthetic Cannabinoids and Their 5 Fluoro Analogs Produce Different Primary Metabolites Metabolite Profiling for AB PINACA and 5F AB PINACA The AAPS Journal 17 3 660 77 doi 10 1208 s12248 015 9721 0 PMC 4406957 PMID 25721194 Cannabinoider foreslas bli klassade som halsofarlig vara Folkhalsomyndigheten Retrieved 24 July 2015 nbsp This cannabinoid related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title 5F NNE1 amp oldid 1205098581, wikipedia, wiki, book, books, library,
