4′-Fluorococaine is a tropane derivative drug which is a synthetic analogue of cocaine. Unlike related compounds such as the corresponding 4′-fluorophenyltropane derivative CFT and the 2′-hydroxy analogue salicylmethylecgonine, 4′-fluorococaine has only around the same potency as cocaine as an inhibitor of dopaminereuptake, but conversely it is a much stronger serotonin reuptake inhibitor than cocaine, resulting in a significantly altered pharmacological profile in animal studies.[1]
^Gatley SJ, Yu DW, Fowler JS, MacGregor RR, Schlyer DJ, Dewey SL, et al. (March 1994). "Studies with differentially labeled [11C]cocaine, [11C]norcocaine, [11C]benzoylecgonine, and [11C]- and 4'-[18F]fluorococaine to probe the extent to which [11C]cocaine metabolites contribute to PET images of the baboon brain". Journal of Neurochemistry. 62 (3): 1154–62. doi:10.1046/j.1471-4159.1994.62031154.x. PMID 8113802. S2CID 25854431.
This article about illegal drug trade is a stub. You can help Wikipedia by expanding it.
fluorococaine, tropane, derivative, drug, which, synthetic, analogue, cocaine, unlike, related, compounds, such, corresponding, fluorophenyltropane, derivative, hydroxy, analogue, salicylmethylecgonine, fluorococaine, only, around, same, potency, cocaine, inhi. 4 Fluorococaine is a tropane derivative drug which is a synthetic analogue of cocaine Unlike related compounds such as the corresponding 4 fluorophenyltropane derivative CFT and the 2 hydroxy analogue salicylmethylecgonine 4 fluorococaine has only around the same potency as cocaine as an inhibitor of dopamine reuptake but conversely it is a much stronger serotonin reuptake inhibitor than cocaine resulting in a significantly altered pharmacological profile in animal studies 1 4 FluorococaineLegal statusLegal statusUK Under Psychoactive Substances Act US Schedule IIIdentifiersIUPAC name methyl 1R 2R 3S 5S 3 4 fluorobenzoyloxy 8 methyl 8 azabicyclo 3 2 1 octane 2 carboxylateCAS Number134507 62 3PubChem CID126112ChemSpider112124 YUNII6045353J3CCompTox Dashboard EPA DTXSID10928640Chemical and physical dataFormulaC 17H 20F N O 4Molar mass321 348 g mol 13D model JSmol Interactive imageSMILES CN1 C H 2CC C H 1 C H C H C2 OC O C3 CC C C C3 F C O OCInChI InChI 1S C17H20FNO4 c1 19 12 7 8 13 19 15 17 21 22 2 14 9 12 23 16 20 10 3 5 11 18 6 4 10 h3 6 12 15H 7 9H2 1 2H3 t12 13 14 15 m0 s1 YKey JRPRINGETIYVSV ZQDZILKHSA N Y verify See also editpFBT Cocaethylene List of cocaine analoguesReferences edit Gatley SJ Yu DW Fowler JS MacGregor RR Schlyer DJ Dewey SL et al March 1994 Studies with differentially labeled 11C cocaine 11C norcocaine 11C benzoylecgonine and 11C and 4 18F fluorococaine to probe the extent to which 11C cocaine metabolites contribute to PET images of the baboon brain Journal of Neurochemistry 62 3 1154 62 doi 10 1046 j 1471 4159 1994 62031154 x PMID 8113802 S2CID 25854431 nbsp This article about illegal drug trade is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title 4 Fluorococaine amp oldid 1162574494, wikipedia, wiki, book, books, library,
