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Wikipedia

2-hydroxyphytanoyl-CoA lyase

2-Hydroxyphytanoyl-CoA lyase is a peroxisomal enzyme involved in the catabolism of phytanoic acid by α-oxidation. It requires thiamine diphosphate (ThDP) as cofactor.[1]

2-hydroxyacyl-CoA lyase 1
Identifiers
SymbolHACL1
Alt. symbolsHPCL
NCBI gene26061
HGNC17856
OMIM604300
RefSeqNM_012260
UniProtQ9UJ83
Other data
LocusChr. 3 p24.3
Search for
StructuresSwiss-model
DomainsInterPro

It is classified under EC number 4.1.

References edit

  1. ^ Foulon V, Antonenkov V, Croes K, et al. (1999). "Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon-carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids". Proc. Natl. Acad. Sci. U.S.A. 96 (18): 10039–44. Bibcode:1999PNAS...9610039F. doi:10.1073/pnas.96.18.10039. PMC 17838. PMID 10468558.

External links edit

  •   Media related to 2-hydroxyphytanoyl-CoA lyase at Wikimedia Commons
  • 2-hydroxyphytanoyl-coenzyme+A+lyase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

hydroxyphytanoyl, lyase, hydroxyphytanoyl, lyase, peroxisomal, enzyme, involved, catabolism, phytanoic, acid, oxidation, requires, thiamine, diphosphate, thdp, cofactor, hydroxyacyl, lyase, 1identifierssymbolhacl1alt, symbolshpclncbi, gene26061hgnc17856omim604. 2 Hydroxyphytanoyl CoA lyase is a peroxisomal enzyme involved in the catabolism of phytanoic acid by a oxidation It requires thiamine diphosphate ThDP as cofactor 1 2 hydroxyacyl CoA lyase 1IdentifiersSymbolHACL1Alt symbolsHPCLNCBI gene26061HGNC17856OMIM604300RefSeqNM 012260UniProtQ9UJ83Other dataLocusChr 3 p24 3Search forStructuresSwiss modelDomainsInterPro It is classified under EC number 4 1 References edit Foulon V Antonenkov V Croes K et al 1999 Purification molecular cloning and expression of 2 hydroxyphytanoyl CoA lyase a peroxisomal thiamine pyrophosphate dependent enzyme that catalyzes the carbon carbon bond cleavage during alpha oxidation of 3 methyl branched fatty acids Proc Natl Acad Sci U S A 96 18 10039 44 Bibcode 1999PNAS 9610039F doi 10 1073 pnas 96 18 10039 PMC 17838 PMID 10468558 External links edit nbsp Media related to 2 hydroxyphytanoyl CoA lyase at Wikimedia Commons 2 hydroxyphytanoyl coenzyme A lyase at the U S National Library of Medicine Medical Subject Headings MeSH Portal nbsp Biology Retrieved from https en wikipedia org w index php title 2 hydroxyphytanoyl CoA lyase amp oldid 1075723824, wikipedia, wiki, book, books, library,

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