Bryan M. Turner is Professor of Experimental Genetics at School of Cancer Sciences, Institute of Biomedical Research, University of Birmingham in Birmingham, UK.
Bryan Turner
Bryan Turner in 2015, portrait via the Royal Society
He was educated at University College London, where he earned his BSc in Biochemistry (1969) and PhD in Human Biochemical Genetics (1973). Before moving to Birmingham University in 1981, he was at the National Institute for Medical Research in Mill Hill (1969–70) and the Mt Sinai School of Medicine in New York (1973–78).[1]
Bryan Turner pioneered the use of antibodies as reagents for research into chromatin and gene expression. He was the first to use synthetic peptides to raise antisera against histones post-translationally acetylated at specific amino acids and showed that these were uniquely powerful reagents for determining the chromosomal distribution of histone modifications. His demonstration that acetylation of a specific lysine on histone H4 marked up-regulated gene transcription of the Drosophila male X chromosome opened the way to a functional understanding of the histone marks. These novel tools allowed him to link histone deacetylation to gene silencing via the discovery that chromosome-wide histone deacetylation distinguishes the inactive X chromosome in female mammals.[2]
Referencesedit
^"Professor Bryan Turner". Birmingham University. Retrieved 4 May 2015.
^"Professor Bryan Turner FMedSci FRS". The Royal Society. Retrieved 4 May 2015.
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bryan, turner, professor, experimental, genetics, school, cancer, sciences, institute, biomedical, research, university, birmingham, birmingham, bryan, turnerbryan, turner, 2015, portrait, royal, societybornalma, materuniversity, college, londonknown, forcontr. Bryan M Turner is Professor of Experimental Genetics at School of Cancer Sciences Institute of Biomedical Research University of Birmingham in Birmingham UK Bryan TurnerBryan Turner in 2015 portrait via the Royal SocietyBornBryan M TurnerAlma materUniversity College LondonKnown forcontributions to epigeneticsAwardsFRS 2015 Scientific careerFieldsGeneticsInstitutionsUniversity of Birmingham He was educated at University College London where he earned his BSc in Biochemistry 1969 and PhD in Human Biochemical Genetics 1973 Before moving to Birmingham University in 1981 he was at the National Institute for Medical Research in Mill Hill 1969 70 and the Mt Sinai School of Medicine in New York 1973 78 1 He has contributed to the field of epigenetics He was elected a Fellow of the Royal Society FRS in 2015 his nomination reads Bryan Turner pioneered the use of antibodies as reagents for research into chromatin and gene expression He was the first to use synthetic peptides to raise antisera against histones post translationally acetylated at specific amino acids and showed that these were uniquely powerful reagents for determining the chromosomal distribution of histone modifications His demonstration that acetylation of a specific lysine on histone H4 marked up regulated gene transcription of the Drosophila male X chromosome opened the way to a functional understanding of the histone marks These novel tools allowed him to link histone deacetylation to gene silencing via the discovery that chromosome wide histone deacetylation distinguishes the inactive X chromosome in female mammals 2 References edit Professor Bryan Turner Birmingham University Retrieved 4 May 2015 Professor Bryan Turner FMedSci FRS The Royal Society Retrieved 4 May 2015 nbsp This article about a British scientist is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Bryan M Turner amp oldid 1083150382, wikipedia, wiki, book, books, library,
