Solute carrier family 12 member 8 (SLC12A8), also known as cation-chloride cotransporter 9 (CCC9), is a protein that in humans is encoded by the SLC12A8gene.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000221955 - Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000035506 - Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: solute carrier family 12 (potassium/chloride transporters)".
^Hewett D, Samuelsson L, Polding J, Enlund F, Smart D, Cantone K, See CG, Chadha S, Inerot A, Enerback C, Montgomery D, Christodolou C, Robinson P, Matthews P, Plumpton M, Wahlstrom J, Swanbeck G, Martinsson T, Roses A, Riley J, Purvis I (March 2002). "Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map". Genomics. 79 (3): 305–14. doi:10.1006/geno.2002.6720. PMID 11863360.
Further readingedit
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC1356129. PMID 16344560.
Adams MD, Kerlavage AR, Fleischmann RD, Fuldner RA, Bult CJ, Lee NH, Kirkness EF, Weinstock KG, Gocayne JD, White O (September 1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence". Nature. 377 (6547 Suppl): 3–174. PMID 7566098.
Daigle ND, Carpentier GA, Frenette-Cotton R, Simard MG, Lefoll MH, Noël M, Caron L, Noël J, Isenring P (September 2009). "Molecular characterization of a human cation-Cl- cotransporter (SLC12A8A, CCC9A) that promotes polyamine and amino acid transport". Journal of Cellular Physiology. 220 (3): 680–9. doi:10.1002/jcp.21814. PMID 19472210. S2CID 28766587.
Hebert SC, Mount DB, Gamba G (February 2004). "Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family". Pflügers Archiv. 447 (5): 580–93. doi:10.1007/s00424-003-1066-3. PMID 12739168. S2CID 21998913.
Hüffmeier U, Lascorz J, Traupe H, Böhm B, Schürmeier-Horst F, Ständer M, Kelsch R, Baumann C, Küster W, Burkhardt H, Reis A (November 2005). "Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris". The Journal of Investigative Dermatology. 125 (5): 906–12. doi:10.1111/j.0022-202X.2005.23847.x. PMID 16297188.
This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.
slc12a8, solute, carrier, family, member, also, known, cation, chloride, cotransporter, ccc9, protein, that, humans, encoded, gene, identifiersaliases, ccc9, solute, carrier, family, member, 8external, idsomim, 611316, 2443672, homologene, 11628, genecards, ge. Solute carrier family 12 member 8 SLC12A8 also known as cation chloride cotransporter 9 CCC9 is a protein that in humans is encoded by the SLC12A8 gene 5 6 SLC12A8IdentifiersAliasesSLC12A8 CCC9 solute carrier family 12 member 8External IDsOMIM 611316 MGI 2443672 HomoloGene 11628 GeneCards SLC12A8Gene location Human Chr Chromosome 3 human 1 Band3q21 2Start125 082 636 bp 1 End125 212 864 bp 1 Gene location Mouse Chr Chromosome 16 mouse 2 Band16 16 B3Start33 337 698 bp 2 End33 484 505 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inright lobe of thyroid glandleft lobe of thyroid glandoocyteparotid glandperiodontal fibergallbladdersecondary oocytebody of pancreaspancreatic ductal cellendothelial cellTop expressed insubmandibular glandparotid glandcrypt of lieberkuhn of small intestineduodenumlarge intestinecolonpyloric antrumileumjejunumgastric mucosaMore reference expression dataBioGPSn aGene ontologyMolecular functionsymporter activity potassium chloride symporter activityCellular componentintegral component of membrane membraneBiological processpotassium ion transport ion transport transmembrane transport potassium ion transmembrane transport cell volume homeostasis chloride ion homeostasis potassium ion homeostasis chloride transmembrane transport potassium ion import across plasma membraneSources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez84561171286EnsemblENSG00000221955ENSMUSG00000035506UniProtA0AV02H7C5L2Q8VI23RefSeq mRNA NM 024628NM 001195483NM 001083902NM 134251NM 001370999RefSeq protein NP 001182412NP 078904NP 001077371NP 599012NP 001357928Location UCSC Chr 3 125 08 125 21 MbChr 16 33 34 33 48 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences edit a b c GRCh38 Ensembl release 89 ENSG00000221955 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000035506 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Entrez Gene solute carrier family 12 potassium chloride transporters Hewett D Samuelsson L Polding J Enlund F Smart D Cantone K See CG Chadha S Inerot A Enerback C Montgomery D Christodolou C Robinson P Matthews P Plumpton M Wahlstrom J Swanbeck G Martinsson T Roses A Riley J Purvis I March 2002 Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map Genomics 79 3 305 14 doi 10 1006 geno 2002 6720 PMID 11863360 Further reading editKimura K Wakamatsu A Suzuki Y Ota T Nishikawa T Yamashita R Yamamoto J Sekine M Tsuritani K Wakaguri H Ishii S Sugiyama T Saito K Isono Y Irie R Kushida N Yoneyama T Otsuka R Kanda K Yokoi T Kondo H Wagatsuma M Murakawa K Ishida S Ishibashi T Takahashi Fujii A Tanase T Nagai K Kikuchi H Nakai K Isogai T Sugano S January 2006 Diversification of transcriptional modulation large scale identification and characterization of putative alternative promoters of human genes Genome Research 16 1 55 65 doi 10 1101 gr 4039406 PMC 1356129 PMID 16344560 Adams MD Kerlavage AR Fleischmann RD Fuldner RA Bult CJ Lee NH Kirkness EF Weinstock KG Gocayne JD White O September 1995 Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence Nature 377 6547 Suppl 3 174 PMID 7566098 Daigle ND Carpentier GA Frenette Cotton R Simard MG Lefoll MH Noel M Caron L Noel J Isenring P September 2009 Molecular characterization of a human cation Cl cotransporter SLC12A8A CCC9A that promotes polyamine and amino acid transport Journal of Cellular Physiology 220 3 680 9 doi 10 1002 jcp 21814 PMID 19472210 S2CID 28766587 Hebert SC Mount DB Gamba G February 2004 Molecular physiology of cation coupled Cl cotransport the SLC12 family Pflugers Archiv 447 5 580 93 doi 10 1007 s00424 003 1066 3 PMID 12739168 S2CID 21998913 Huffmeier U Lascorz J Traupe H Bohm B Schurmeier Horst F Stander M Kelsch R Baumann C Kuster W Burkhardt H Reis A November 2005 Systematic linkage disequilibrium analysis of SLC12A8 at PSORS5 confirms a role in susceptibility to psoriasis vulgaris The Journal of Investigative Dermatology 125 5 906 12 doi 10 1111 j 0022 202X 2005 23847 x PMID 16297188 nbsp This article on a gene on human chromosome 3 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title SLC12A8 amp oldid 1142698982, wikipedia, wiki, book, books, library,
