^Jain KK (14 February 2011). The Handbook of Neuroprotection. Springer Science & Business Media. pp. 154–. ISBN978-1-61779-049-2.
^Ray A, Gulati K (1 January 2007). Current Trends in Pharmacology. I. K. International Pvt Ltd. pp. 321–. ISBN978-81-88237-77-7.
^Waxman S (27 May 2005). Multiple Sclerosis As A Neuronal Disease. Academic Press. pp. 245–. ISBN978-0-08-048941-4.
^Gill S, Pulido O (31 January 2007). Glutamate Receptors in Peripheral Tissue: Excitatory Transmission Outside the CNS. Springer Science & Business Media. pp. 37–. ISBN978-0-306-48644-9.
^Farooqui AA (2 September 2010). Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases. Springer Science & Business Media. pp. 73–. ISBN978-1-4419-6652-0.
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zonampanel, code, name, ym872, quinoxalinedione, derivative, drug, competitive, antagonist, ampa, receptor, which, being, investigated, yamanouchi, astellas, pharma, neuroprotective, drug, treatment, ischemic, stroke, never, completed, clinical, trials, clinic. Zonampanel INN code name YM872 is a quinoxalinedione derivative drug and competitive antagonist of the AMPA receptor which was being investigated by Yamanouchi Astellas Pharma as a neuroprotective drug for the treatment of ischemic stroke but never completed clinical trials 1 2 3 4 In clinical trials zonampanel produced severe side effects including hallucinations agitation and catatonia in patients resulting in early termination of the trials 5 ZonampanelClinical dataATC codeNoneIdentifiersIUPAC name 7 1H Imidazol 1 yl 6 nitro 2 3 dioxo 3 4 dihydro 1 2H quinoxalinyl acetic acidCAS Number210245 80 0PubChem CID148200ChemSpider130649UNII9X33544ILSCompTox Dashboard EPA DTXSID50175232Chemical and physical dataFormulaC 13H 9N 5O 6Molar mass331 244 g mol 13D model JSmol Interactive imageSMILES c1cn cn1 c2cc3c cc2 N O O nH c O c O n3CC O OInChI InChI 1S C13H9N5O6 c19 11 20 5 17 8 4 9 16 2 1 14 6 16 10 18 23 24 3 7 8 15 12 21 13 17 22 h1 4 6H 5H2 H 15 21 H 19 20 Key SPXYHZRWPRQLNS UHFFFAOYSA NReferences edit Jain KK 14 February 2011 The Handbook of Neuroprotection Springer Science amp Business Media pp 154 ISBN 978 1 61779 049 2 Ray A Gulati K 1 January 2007 Current Trends in Pharmacology I K International Pvt Ltd pp 321 ISBN 978 81 88237 77 7 Waxman S 27 May 2005 Multiple Sclerosis As A Neuronal Disease Academic Press pp 245 ISBN 978 0 08 048941 4 Gill S Pulido O 31 January 2007 Glutamate Receptors in Peripheral Tissue Excitatory Transmission Outside the CNS Springer Science amp Business Media pp 37 ISBN 978 0 306 48644 9 Farooqui AA 2 September 2010 Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases Springer Science amp Business Media pp 73 ISBN 978 1 4419 6652 0 nbsp This drug article relating to the nervous system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Zonampanel amp oldid 1132982979, wikipedia, wiki, book, books, library,