Zinc finger proteins (ZNFs), such as ZNF208, bind DNA and, through this binding, regulate gene transcription. Most ZNFs contain conserved C2H2 motifs and are classified as Kruppel-type zinc fingers. A conserved protein motif, termed the Kruppel-associated box (KRAB) domain, mediates protein-protein interactions (Eichler et al., 1998 [PubMed 9724325]). See ZNF91 (MIM 603971) for further information on ZNFs.
Referencesedit
^ abcGRCh38: Ensembl release 89: ENSG00000160321 - Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000068959 - Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Zinc finger protein 208". Retrieved 2016-01-28.
zinc, finger, protein, protein, that, humans, encoded, znf208, gene, znf208identifiersaliasesznf208, pmidp, znf95, zinc, finger, protein, 208external, idsomim, 603977, 1917477, homologene, 133818, genecards, znf208gene, location, human, chromosome, human, band. Zinc finger protein 208 is a protein that in humans is encoded by the ZNF208 gene 5 ZNF208IdentifiersAliasesZNF208 PMIDP ZNF95 zinc finger protein 208External IDsOMIM 603977 MGI 1917477 HomoloGene 133818 GeneCards ZNF208Gene location Human Chr Chromosome 19 human 1 Band19p12Start21 932 958 bp 1 End22 010 949 bp 1 Gene location Mouse Chr Chromosome 7 mouse 2 Band7 7 B3Start39 167 190 bp 2 End39 189 844 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inleft ventricleanterior pituitaryleft lobe of thyroid glandislet of Langerhansright uterine tuberight lobe of thyroid glandleft coronary arteryleft uterine tubeascending aortasmooth muscle tissueTop expressed intrigeminal ganglionmedial ganglionic eminencetriceps brachii muscledigastric musclevastus lateralis musclecarotid bodysuperior frontal gyrusneural tubesternocleidomastoid muscletemporal muscleMore reference expression dataBioGPSn aGene ontologyMolecular functionDNA binding zinc ion binding metal ion binding nucleic acid binding DNA binding transcription factor activity RNA polymerase II specificCellular componentintracellular anatomical structure nucleusBiological processregulation of transcription DNA templated transcription DNA templated regulation of transcription by RNA polymerase IISources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez775770227EnsemblENSG00000160321ENSMUSG00000068959UniProtO43345n aRefSeq mRNA NM 001329971NM 001329972NM 001329973NM 001329974NM 007153NM 001004139RefSeq protein NP 001316900NP 001316901NP 001316902NP 001316903NP 009084n aLocation UCSC Chr 19 21 93 22 01 MbChr 7 39 17 39 19 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseFunction editZinc finger proteins ZNFs such as ZNF208 bind DNA and through this binding regulate gene transcription Most ZNFs contain conserved C2H2 motifs and are classified as Kruppel type zinc fingers A conserved protein motif termed the Kruppel associated box KRAB domain mediates protein protein interactions Eichler et al 1998 PubMed 9724325 See ZNF91 MIM 603971 for further information on ZNFs References edit a b c GRCh38 Ensembl release 89 ENSG00000160321 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000068959 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Entrez Gene Zinc finger protein 208 Retrieved 2016 01 28 Further reading editThis article incorporates text from the United States National Library of Medicine which is in the public domain nbsp This article on a gene on human chromosome 19 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Zinc finger protein 208 amp oldid 1167414518, wikipedia, wiki, book, books, library,
