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Wikipedia

ATBF1

April 18, 2024

Zinc finger homeobox protein 3 is a protein that in humans is encoded by the ZFHX3 gene.[5][6][7]

ZFHX3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesZFHX3, ATBF1, ATBT, ZNF927, zinc finger homeobox 3
External IDsOMIM: 104155 MGI: 99948 HomoloGene: 21366 GeneCards: ZFHX3
Orthologs
SpeciesHumanMouse
Entrez

463

11906

Ensembl

ENSG00000140836

ENSMUSG00000038872

UniProt

Q15911

Q61329

RefSeq (mRNA)

NM_001164766
NM_006885

NM_007496

RefSeq (protein)

NP_001158238
NP_008816

n/a

Location (UCSC)Chr 16: 72.78 – 73.89 MbChr 8: 108.67 – 109.69 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


References edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000140836 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038872 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Morinaga T, Yasuda H, Hashimoto T, Higashio K, Tamaoki T (Dec 1991). "A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers". Mol Cell Biol. 11 (12): 6041–9. doi:10.1128/MCB.11.12.6041. PMC 361769. PMID 1719379.
  6. ^ Miura Y, Tam T, Ido A, Morinaga T, Miki T, Hashimoto T, Tamaoki T (Dec 1995). "Cloning and characterization of an ATBF1 isoform that expresses in a neuronal differentiation-dependent manner". J Biol Chem. 270 (45): 26840–8. doi:10.1074/jbc.270.45.26840. PMID 7592926.
  7. ^ "Entrez Gene: ATBF1 AT-binding transcription factor 1".

Further reading edit

  • Yamada K, Miura Y, Scheidl T, et al. (1996). "Assignment of the human ATBF1 transcription factor gene to chromosome 16q22.3-q23.1". Genomics. 29 (2): 552–3. doi:10.1006/geno.1995.9967. PMID 8666409.
  • Bedford MT, Chan DC, Leder P (1997). "FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands". EMBO J. 16 (9): 2376–83. doi:10.1093/emboj/16.9.2376. PMC 1169838. PMID 9171351.
  • Kaspar P, Dvoráková M, Králová J, et al. (1999). "Myb-interacting protein, ATBF1, represses transcriptional activity of Myb oncoprotein". J. Biol. Chem. 274 (20): 14422–8. doi:10.1074/jbc.274.20.14422. PMID 10318867.
  • Loftus BJ, Kim UJ, Sneddon VP, et al. (1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. 60 (3): 295–308. doi:10.1006/geno.1999.5927. PMID 10493829.
  • Kaushik N, Malaspina A, de Belleroche J (2000). "Characterization of trinucleotide- and tandem repeat-containing transcripts obtained from human spinal cord cDNA library by high-density filter hybridization". DNA Cell Biol. 19 (5): 265–73. doi:10.1089/10445490050021177. PMID 10855793.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Iida M, Imura J, Furuichi T, et al. (2004). "Alteration of the AT motif binding factor-1 expression in alpha-fetoprotein producing gastric cancer: is it an event for differentiation and proliferation of the tumors?". Oncol. Rep. 11 (1): 3–7. doi:10.3892/or.11.1.3. PMID 14654895.
  • Nojiri S, Joh T, Miura Y, et al. (2004). "ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3". Biochem. Biophys. Res. Commun. 314 (1): 97–103. doi:10.1016/j.bbrc.2003.12.054. PMID 14715251.
  • Martin J, Han C, Gordon LA, et al. (2005). "The sequence and analysis of duplication-rich human chromosome 16". Nature. 432 (7020): 988–94. Bibcode:2004Natur.432..988M. doi:10.1038/nature03187. PMID 15616553.
  • Zhang Z, Yamashita H, Toyama T, et al. (2005). "ATBF1-a messenger RNA expression is correlated with better prognosis in breast cancer". Clin. Cancer Res. 11 (1): 193–8. doi:10.1158/1078-0432.193.11.1. PMID 15671546.
  • Sun X, Frierson HF, Chen C, et al. (2005). "Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer". Nat. Genet. 37 (4): 407–12. doi:10.1038/ng1528. PMID 15750593. S2CID 19458711.
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
  • Xu J, Sauvageot J, Ewing CM, et al. (2006). "Germline ATBF1 mutations and prostate cancer risk". Prostate. 66 (10): 1082–5. doi:10.1002/pros.20430. PMID 16637072. S2CID 21238472.
  • Sun X, Zhou Y, Otto KB, et al. (2007). "Infrequent mutation of ATBF1 in human breast cancer". J. Cancer Res. Clin. Oncol. 133 (2): 103–5. doi:10.1007/s00432-006-0148-y. PMID 16932943. S2CID 12378418.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
  • Mori Y, Kataoka H, Miura Y, et al. (2007). "Subcellular localization of ATBF1 regulates MUC5AC transcription in gastric cancer". Int. J. Cancer. 121 (2): 241–7. doi:10.1002/ijc.22654. PMID 17330845. S2CID 37176312.
  • Cho YG, Song JH, Kim CJ, et al. (2007). "Genetic alterations of the ATBF1 gene in gastric cancer". Clin. Cancer Res. 13 (15 Pt 1): 4355–9. doi:10.1158/1078-0432.CCR-07-0619. PMID 17671116.

External links edit


 

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

April 18, 2024
atbf1, zinc, finger, homeobox, protein, protein, that, humans, encoded, zfhx3, gene, zfhx3available, structurespdbortholog, search, pdbe, rcsblist, codes2da1, 2da2, 2da3identifiersaliaseszfhx3, atbt, znf927, zinc, finger, homeobox, 3external, idsomim, 104155, . Zinc finger homeobox protein 3 is a protein that in humans is encoded by the ZFHX3 gene 5 6 7 ZFHX3Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes2DA1 2DA2 2DA3IdentifiersAliasesZFHX3 ATBF1 ATBT ZNF927 zinc finger homeobox 3External IDsOMIM 104155 MGI 99948 HomoloGene 21366 GeneCards ZFHX3Gene location Human Chr Chromosome 16 human 1 Band16q22 2 q22 3Start72 782 885 bp 1 End73 891 871 bp 1 Gene location Mouse Chr Chromosome 8 mouse 2 Band8 8 D3Start108 669 276 bp 2 End109 688 262 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed insaphenous veinsynovial jointpericardiumurethratrigeminal ganglionspinal ganglialower lobe of lungseminal vesiculahuman penisrenal medullaTop expressed inascending aortaaortic valveexternal carotid arterylacrimal glandinternal carotid arteryciliary bodysuperior cervical ganglionstria vascularisconjunctival fornixmedial dorsal nucleusMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular functionDNA binding sequence specific DNA binding DNA binding transcription factor activity zinc ion binding metal ion binding core promoter sequence specific DNA binding protein binding nucleic acid binding enzyme binding transcription factor activity RNA polymerase II distal enhancer sequence specific binding RNA polymerase II cis regulatory region sequence specific DNA binding DNA binding transcription repressor activity RNA polymerase II specific DNA binding transcription factor activity RNA polymerase II specificCellular componentcytoplasm nuclear body transcription regulator complex nucleus nucleoplasmBiological processnegative regulation of myoblast differentiation regulation of transcription DNA templated regulation of locomotor rhythm muscle organ development transcription by RNA polymerase II circadian regulation of gene expression transcription DNA templated positive regulation of transcription DNA templated positive regulation of myoblast differentiation negative regulation of transcription DNA templated response to transforming growth factor beta negative regulation of transcription by RNA polymerase II brain development regulation of neuron differentiation positive regulation of cell adhesion positive regulation of transcription by RNA polymerase IISources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez46311906EnsemblENSG00000140836ENSMUSG00000038872UniProtQ15911Q61329RefSeq mRNA NM 001164766NM 006885NM 007496RefSeq protein NP 001158238NP 008816n aLocation UCSC Chr 16 72 78 73 89 MbChr 8 108 67 109 69 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences edit a b c GRCh38 Ensembl release 89 ENSG00000140836 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000038872 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Morinaga T Yasuda H Hashimoto T Higashio K Tamaoki T Dec 1991 A human alpha fetoprotein enhancer binding protein ATBF1 contains four homeodomains and seventeen zinc fingers Mol Cell Biol 11 12 6041 9 doi 10 1128 MCB 11 12 6041 PMC 361769 PMID 1719379 Miura Y Tam T Ido A Morinaga T Miki T Hashimoto T Tamaoki T Dec 1995 Cloning and characterization of an ATBF1 isoform that expresses in a neuronal differentiation dependent manner J Biol Chem 270 45 26840 8 doi 10 1074 jbc 270 45 26840 PMID 7592926 Entrez Gene ATBF1 AT binding transcription factor 1 Further reading editYamada K Miura Y Scheidl T et al 1996 Assignment of the human ATBF1 transcription factor gene to chromosome 16q22 3 q23 1 Genomics 29 2 552 3 doi 10 1006 geno 1995 9967 PMID 8666409 Bedford MT Chan DC Leder P 1997 FBP WW domains and the Abl SH3 domain bind to a specific class of proline rich ligands EMBO J 16 9 2376 83 doi 10 1093 emboj 16 9 2376 PMC 1169838 PMID 9171351 Kaspar P Dvorakova M Kralova J et al 1999 Myb interacting protein ATBF1 represses transcriptional activity of Myb oncoprotein J Biol Chem 274 20 14422 8 doi 10 1074 jbc 274 20 14422 PMID 10318867 Loftus BJ Kim UJ Sneddon VP et al 1999 Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q Genomics 60 3 295 308 doi 10 1006 geno 1999 5927 PMID 10493829 Kaushik N Malaspina A de Belleroche J 2000 Characterization of trinucleotide and tandem repeat containing transcripts obtained from human spinal cord cDNA library by high density filter hybridization DNA Cell Biol 19 5 265 73 doi 10 1089 10445490050021177 PMID 10855793 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Iida M Imura J Furuichi T et al 2004 Alteration of the AT motif binding factor 1 expression in alpha fetoprotein producing gastric cancer is it an event for differentiation and proliferation of the tumors Oncol Rep 11 1 3 7 doi 10 3892 or 11 1 3 PMID 14654895 Nojiri S Joh T Miura Y et al 2004 ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3 Biochem Biophys Res Commun 314 1 97 103 doi 10 1016 j bbrc 2003 12 054 PMID 14715251 Martin J Han C Gordon LA et al 2005 The sequence and analysis of duplication rich human chromosome 16 Nature 432 7020 988 94 Bibcode 2004Natur 432 988M doi 10 1038 nature03187 PMID 15616553 Zhang Z Yamashita H Toyama T et al 2005 ATBF1 a messenger RNA expression is correlated with better prognosis in breast cancer Clin Cancer Res 11 1 193 8 doi 10 1158 1078 0432 193 11 1 PMID 15671546 Sun X Frierson HF Chen C et al 2005 Frequent somatic mutations of the transcription factor ATBF1 in human prostate cancer Nat Genet 37 4 407 12 doi 10 1038 ng1528 PMID 15750593 S2CID 19458711 Rual JF Venkatesan K Hao T et al 2005 Towards a proteome scale map of the human protein protein interaction network Nature 437 7062 1173 8 Bibcode 2005Natur 437 1173R doi 10 1038 nature04209 PMID 16189514 S2CID 4427026 Xu J Sauvageot J Ewing CM et al 2006 Germline ATBF1 mutations and prostate cancer risk Prostate 66 10 1082 5 doi 10 1002 pros 20430 PMID 16637072 S2CID 21238472 Sun X Zhou Y Otto KB et al 2007 Infrequent mutation of ATBF1 in human breast cancer J Cancer Res Clin Oncol 133 2 103 5 doi 10 1007 s00432 006 0148 y PMID 16932943 S2CID 12378418 Olsen JV Blagoev B Gnad F et al 2006 Global in vivo and site specific phosphorylation dynamics in signaling networks Cell 127 3 635 48 doi 10 1016 j cell 2006 09 026 PMID 17081983 S2CID 7827573 Mori Y Kataoka H Miura Y et al 2007 Subcellular localization of ATBF1 regulates MUC5AC transcription in gastric cancer Int J Cancer 121 2 241 7 doi 10 1002 ijc 22654 PMID 17330845 S2CID 37176312 Cho YG Song JH Kim CJ et al 2007 Genetic alterations of the ATBF1 gene in gastric cancer Clin Cancer Res 13 15 Pt 1 4355 9 doi 10 1158 1078 0432 CCR 07 0619 PMID 17671116 External links editATBF1 protein human at the U S National Library of Medicine Medical Subject Headings MeSH Human ZFHX3 genome location and ZFHX3 gene details page in the UCSC Genome Browser nbsp This article on a gene on human chromosome 16 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title ATBF1 amp oldid 1184068893, wikipedia, wiki, book, books, library,

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