Xylomannan is an antifreeze molecule, found in the freeze-tolerant Alaskan beetle Upis ceramboides.[1] Unlike antifreeze proteins, xylomannan is not a protein. Instead, it is a combination of a sugar (saccharide) and a fatty acid that is found in cell membranes.[2] As such is expected to work in a different manner than AFPs. It is believed to work by incorporating itself directly into the cell membrane and preventing the freezing of water molecules within the cell.[3]
^Ishiwata A, Sakurai A, Nishimiya Y, Tsuda S, Ito Y (Dec 7, 2011). "Synthetic study and structural analysis of the antifreeze agent xylomannan from Upis ceramboides". J Am Chem Soc. 133 (48): 19524–35. doi:10.1021/ja208528c. PMID 22029271.
^Damonte E, Neyts J, Pujol CA, et al. (June 1994). "Antiviral activity of a sulphated polysaccharide from the red seaweed Nothogenia fastigiata". Biochemical Pharmacology. 47 (12): 2187–92. doi:10.1016/0006-2952(94)90254-2. PMID 8031312.
March 04, 2023
xylomannan, antifreeze, molecule, found, freeze, tolerant, alaskan, beetle, upis, ceramboides, unlike, antifreeze, proteins, xylomannan, protein, instead, combination, sugar, saccharide, fatty, acid, that, found, cell, membranes, such, expected, work, differen. Xylomannan is an antifreeze molecule found in the freeze tolerant Alaskan beetle Upis ceramboides 1 Unlike antifreeze proteins xylomannan is not a protein Instead it is a combination of a sugar saccharide and a fatty acid that is found in cell membranes 2 As such is expected to work in a different manner than AFPs It is believed to work by incorporating itself directly into the cell membrane and preventing the freezing of water molecules within the cell 3 Xylomannan is also found in the red seaweed Nothogenia fastigiata Scinaiaceae family Fraction F6 of a sulphated xylomannan from Nothogenia fastigiata was found to inhibit replication of a variety of viruses including Herpes simplex virus types 1 and 2 HSV 1 HSV 2 Human cytomegalovirus HCMV HHV 5 Respiratory syncytial virus RSV Influenzavirus A Influenzavirus B Junin and Tacaribe virus Simian immunodeficiency virus and weakly Human immunodeficiency virus types 1 and 2 4 References Edit Walters KR Jr Serianni AS Sformo T Barnes BM Duman JG 2009 A nonprotein thermal hysteresis producing xylomannan antifreeze in the freeze tolerant Alaskan beetle Upis ceramboides PNAS 106 48 20210 5 Bibcode 2009PNAS 10620210W doi 10 1073 pnas 0909872106 PMC 2787118 PMID 19934038 Ishiwata A Sakurai A Nishimiya Y Tsuda S Ito Y Dec 7 2011 Synthetic study and structural analysis of the antifreeze agent xylomannan from Upis ceramboides J Am Chem Soc 133 48 19524 35 doi 10 1021 ja208528c PMID 22029271 New Antifreeze Molecule Isolated In Alaska Beetle Science News redOrbit Damonte E Neyts J Pujol CA et al June 1994 Antiviral activity of a sulphated polysaccharide from the red seaweed Nothogenia fastigiata Biochemical Pharmacology 47 12 2187 92 doi 10 1016 0006 2952 94 90254 2 PMID 8031312 Retrieved from https en wikipedia org w index php title Xylomannan amp oldid 1126499155, wikipedia, wiki, book, books, library,
