WormBook

This article is about the online review of nematode biology. For the fictional web serial, see Worm (web serial).

WormBook is an open access, comprehensive collection of original, peer-reviewed chapters covering topics related to the biology of the nematode worm Caenorhabditis elegans (C. elegans). WormBook also includes WormMethods, an up-to-date collection of methods and protocols for C. elegans researchers.^[1][2][3][4]

WormBook.org

The online review of C. elegans biology
Published	2005
Website	wormbook.org genetics.org/content/wormbook www.ncbi.nlm.nih.gov/books/NBK19662/

WormBook is the online text companion to WormBase,^[5] the C. elegans model organism database. Capitalizing on the World Wide Web, WormBook links in-text references (e.g. genes, alleles, proteins, literature citations) with primary biological databases such as WormBase and PubMed. C. elegans was the first multicellular organism to have its genome sequenced^[6] and is a model organism for studying developmental genetics and neurobiology.

Contents

The content of WormBook is categorized into the sections listed below, each filled with a variety of relevant chapters. These sections include:

• Genetics and genomics^[7]
• Molecular biology
• Biochemistry
• Cell Biology
• Signal transduction^[8]
• Developmental biology
• Post-embryonic development
• Sex-determination systems^[9]
• The germ line^[10]
• Neurobiology and behavior
• Evolution and ecology^[11]
• Disease models and drug discovery
• WormMethods

References

1. "The WormBook website". wormbook.org.
2. White, John Graham (2013). "Getting into the mind of a worm—a personal view". WormBook: 1–10. doi:10.1895/wormbook.1.158.1. PMC 4781474. PMID 23801597.  
3. Corsi, Ann K. (2015). "A Transparent window into biology: A primer on Caenorhabditis elegans". WormBook: 1–31. doi:10.1895/wormbook.1.177.1. ISSN 1551-8507. PMC 4781331. PMID 26087236.
4. Greenwald, I. (2016). "WormBook: WormBiology for the 21st Century". Genetics. 202 (3): 883–884. doi:10.1534/genetics.116.187575. ISSN 0016-6731. PMC 4788125. PMID 26953267.
5. Howe, Kevin L.; Bolt, Bruce J.; Cain, Scott; Chan, Juancarlos; Chen, Wen J.; Davis, Paul; Done, James; Down, Thomas; Gao, Sibyl; Grove, Christian; Harris, Todd W.; Kishore, Ranjana; Lee, Raymond; Lomax, Jane; Li, Yuling; Muller, Hans-Michael; Nakamura, Cecilia; Nuin, Paulo; Paulini, Michael; Raciti, Daniela; Schindelman, Gary; Stanley, Eleanor; Tuli, Mary Ann; Van Auken, Kimberly; Wang, Daniel; Wang, Xiaodong; Williams, Gary; Wright, Adam; Yook, Karen; Berriman, Matthew; Kersey, Paul; Schedl, Tim; Stein, Lincoln; Sternberg, Paul W. (2016). "WormBase 2016: expanding to enable helminth genomic research". Nucleic Acids Research. 44 (D1): D774–D780. doi:10.1093/nar/gkv1217. PMC 4702863. PMID 26578572.  
6. The C. elegans Sequencing Consortium (1998). "Genome sequence of the nematode C. elegans: A platform for investigating biology". Science. 282 (5396): 2012–2018. Bibcode:1998Sci...282.2012.. doi:10.1126/science.282.5396.2012. PMID 9851916.
7. Hodgkin, Jonathan (2005). "Introduction to genetics and genomics". WormBook. doi:10.1895/wormbook.1.17.1.
8. Greenwald, Iva (2005). "Introduction to signal transduction". WormBook. doi:10.1895/wormbook.1.20.1.
9. Herman, Robert (2005). "Introduction to sex determination". WormBook. doi:10.1895/wormbook.1.71.1.
10. Hubbard, E. Jane (2005). "Introduction to the germ line". WormBook: 1–4. doi:10.1895/wormbook.1.18.1. PMC 4781435. PMID 18050415.
11. Fitch, David H.A. (2005). "Introduction to nematode evolution and ecology". WormBook: 1–8. doi:10.1895/wormbook.1.19.1. PMC 4781023. PMID 18050395.