Dr. Harry John Clayton (ca.1887 – 31 October 1928)[1] of Macquarie Street and medical superintendent of the Royal Prince Alfred Hospital, Sydney, took the headache remedy then in general use, composed of phenacetin and caffeine, and by experimenting with the addition of aspirin, arrived at what became the standard formulation known as A.P.C. powder, or in the Royal Prince Alfred Hospital Pharmacopæia for 1918 as Pulvis Analgesicus.
In 1919, at the insistence of his wife, Clayton founded a partnership consisting of Mrs Clayton, E. W. Wills, C. K. Probert (dispenser at the Royal Prince Alfred Hospital), and J. A. Vincent (1890 – 12 June 1933), who had been assistant dispenser at the hospital, and was at that time a pharmacist with a business at Five Dock. Clayton chose the names "Vincent Chemical Company" and "Vincent's APC" to distance himself, as a practicing physician, from any commercial product. During the pneumonic influenza epidemic April to July 1919, he offered many of his customers packages of the compound as A.P.C. powder, which may have been labeled "Vincent's A.P.C." The partnership was incorporated on 11 September 1919 with paid-up capital of £200; £50 from each of the partners; later doubled to total £400. Vincent made up the compound, coloured pink, in premises adjacent to his chemist's shop, as 12 envelopes of powder in a box, or as 24 tablets in a small bottle, and labeled as "pain remedy". Printed instructions for use, supplied gratis by Clayton, were included with each package, bearing the company's trademark "Vincent's APC". The business did not thrive initially, at least in part due to insufficient advertising, and in May 1921 Vincent sold his share of the business (as did Wills) to Probert and Mrs. Clayton, and left for America to train as a dentist, selling his chemist's shop and passing the fledgling manufacturing business to wholesale druggist William Delany. After several months of supplying Clayton and Probert with the product, he was brought into the partnership. In July 1923 the business was re-formed with three owners, Dora Lauraine Clayton, Minnie Probert and Harriett Delany, with joint managers Mr. Probert and Mr. Delany, and in that year the company first showed a profit. They registered their trademark "Vincent's APC" on 21 July 1930, and invested heavily in advertising: £2575 in 1931, £3367 in 1932 and £4703 in 1933, in which year they made a profit of £18,400.[2] The trademark design changed little from this time: "VINCENT'S" in white lettering on a blue rectangle, with "A•P•C" in white on a blue semicircle attached directly below, and "GENUINE (PINK)" in blue on a yellow semicircle attached above.[3]
Return of Dr. Vincent
In 1924, Vincent returned to Sydney, having qualified as Doctor of Dental Surgery, and opened a practice in Haberfield. He was still on friendly terms with Probert, and intimated to him that he would like to rejoin the partnership, and on 8 March 1926 wrote to them with an offer, intimating that he had other products with which they could diversify, to which Delany replied on 10 March, stating that none of the shareholders was interested in his proposal, concluding ominously: "As you mention that you are desirous of putting certain new lines of chemical preparations on the Australian market, I have to remind you that perhaps the most valuable asset of the Vincent Chemical Company in this field is now its trademark ... and that it could not permit this asset to be challenged or imperilled."[2]
In September 1932, Dr. Vincent, who had invented an analgesic toothpaste, founded a company Vincent's Products, Ltd., with a nominal capital of £1000, to manufacture and market this product. Dr. Vincent was originally appointed managing director, but died shortly after, and his widow Hilda A. Vincent (née Mills) was appointed in his place. In 1934 Vincent Chemical Co. sued Vincent's Products, Ltd. for infringement of their trademark. The court upheld the complaint and issued a limited injunction against the defendant from using that name in circumstances which might lead customers to believe the companies were associated, and awarded costs against Vincent's Products, Ltd.[2]
Around 1936, Vincent's APC was first also marketed in "pocket-size" rectangular cans containing 24 tablets.[4]
1941: The same today as in 1917 ... Take Vincent's with confidence.[6]
1950s: Take Vincent's with confidence for quick three-way relief Vincent's radio jingles (YouTube)
late 1970s - "It's your day, don't share it with a headache! Vincents helps when you need help with pain." (sung)[citation needed]
Phenacetin dropped
At some time before 1972 Vincent Chemical Co. replaced the phenacetin in the formulation of its powders and tablets with salicylamide.[7] Compound analgesics were banned in Australia in 1979 due to analgesic nephropathy.[8] Phenacetin, a pain-relieving and fever-reducing drug, was banned by the FDA in the US in 1983, due to its adverse effects, which include kidney damage (as shown by Dr. Priscilla Kincaid-Smith)[9][10] and cancer.[11] It was replaced in many other medications by its metabolite, paracetamol.
^Morrow, Claire (1 October 2009). "The dangers of self-medicating: mother's little helpers don't always have a desirable effect, warns Claire Morrow. (Feel Life: Health)". Investigate. Howling at the Moon Publishing Ltd. 9 (105): 76(2). ISSN 1832-2794. Stressful Day? What you need is a cup of tea, a Bex and a good lie down. So the advertising went, in the days of powders. When I worked in aged care it was not uncommon to come across an elderl ....
^"Bex Powders". School of Medical Sciences UNSW. Retrieved 15 June 2018.
^Dunlevy, Sue (29 August 2014). "Cancer Council NSW: Bex powder killed more than pain". news.com.au. News Corp Australian Network. Retrieved 31 March 2018.
January 06, 2023
vincent, chemical, vincent, chemical, company, australian, business, noted, manufacture, popular, compound, analgesic, vincent, contents, history, return, vincent, advertising, slogans, phenacetin, dropped, also, referenceshistory, editdr, harry, john, clayton. Vincent Chemical Company was an Australian business noted for manufacture of a popular compound analgesic Vincent s APC Contents 1 History 2 Return of Dr Vincent 3 Advertising slogans 4 Phenacetin dropped 5 See also 6 ReferencesHistory EditDr Harry John Clayton ca 1887 31 October 1928 1 of Macquarie Street and medical superintendent of the Royal Prince Alfred Hospital Sydney took the headache remedy then in general use composed of phenacetin and caffeine and by experimenting with the addition of aspirin arrived at what became the standard formulation known as A P C powder or in the Royal Prince Alfred Hospital Pharmacopaeia for 1918 as Pulvis Analgesicus In 1919 at the insistence of his wife Clayton founded a partnership consisting of Mrs Clayton E W Wills C K Probert dispenser at the Royal Prince Alfred Hospital and J A Vincent 1890 12 June 1933 who had been assistant dispenser at the hospital and was at that time a pharmacist with a business at Five Dock Clayton chose the names Vincent Chemical Company and Vincent s APC to distance himself as a practicing physician from any commercial product During the pneumonic influenza epidemic April to July 1919 he offered many of his customers packages of the compound as A P C powder which may have been labeled Vincent s A P C The partnership was incorporated on 11 September 1919 with paid up capital of 200 50 from each of the partners later doubled to total 400 Vincent made up the compound coloured pink in premises adjacent to his chemist s shop as 12 envelopes of powder in a box or as 24 tablets in a small bottle and labeled as pain remedy Printed instructions for use supplied gratis by Clayton were included with each package bearing the company s trademark Vincent s APC The business did not thrive initially at least in part due to insufficient advertising and in May 1921 Vincent sold his share of the business as did Wills to Probert and Mrs Clayton and left for America to train as a dentist selling his chemist s shop and passing the fledgling manufacturing business to wholesale druggist William Delany After several months of supplying Clayton and Probert with the product he was brought into the partnership In July 1923 the business was re formed with three owners Dora Lauraine Clayton Minnie Probert and Harriett Delany with joint managers Mr Probert and Mr Delany and in that year the company first showed a profit They registered their trademark Vincent s APC on 21 July 1930 and invested heavily in advertising 2575 in 1931 3367 in 1932 and 4703 in 1933 in which year they made a profit of 18 400 2 The trademark design changed little from this time VINCENT S in white lettering on a blue rectangle with A P C in white on a blue semicircle attached directly below and GENUINE PINK in blue on a yellow semicircle attached above 3 Return of Dr Vincent EditIn 1924 Vincent returned to Sydney having qualified as Doctor of Dental Surgery and opened a practice in Haberfield He was still on friendly terms with Probert and intimated to him that he would like to rejoin the partnership and on 8 March 1926 wrote to them with an offer intimating that he had other products with which they could diversify to which Delany replied on 10 March stating that none of the shareholders was interested in his proposal concluding ominously As you mention that you are desirous of putting certain new lines of chemical preparations on the Australian market I have to remind you that perhaps the most valuable asset of the Vincent Chemical Company in this field is now its trademark and that it could not permit this asset to be challenged or imperilled 2 In September 1932 Dr Vincent who had invented an analgesic toothpaste founded a company Vincent s Products Ltd with a nominal capital of 1000 to manufacture and market this product Dr Vincent was originally appointed managing director but died shortly after and his widow Hilda A Vincent nee Mills was appointed in his place In 1934 Vincent Chemical Co sued Vincent s Products Ltd for infringement of their trademark The court upheld the complaint and issued a limited injunction against the defendant from using that name in circumstances which might lead customers to believe the companies were associated and awarded costs against Vincent s Products Ltd 2 Around 1936 Vincent s APC was first also marketed in pocket size rectangular cans containing 24 tablets 4 Advertising slogans Edit1928 Take genuine Vincent s powders 1938 For safety s sake take Vincent s APC 5 1941 The same today as in 1917 Take Vincent s with confidence 6 1950s Take Vincent s with confidence for quick three way relief Vincent s radio jingles YouTube late 1970s It s your day don t share it with a headache Vincents helps when you need help with pain sung citation needed Phenacetin dropped EditAt some time before 1972 Vincent Chemical Co replaced the phenacetin in the formulation of its powders and tablets with salicylamide 7 Compound analgesics were banned in Australia in 1979 due to analgesic nephropathy 8 Phenacetin a pain relieving and fever reducing drug was banned by the FDA in the US in 1983 due to its adverse effects which include kidney damage as shown by Dr Priscilla Kincaid Smith 9 10 and cancer 11 It was replaced in many other medications by its metabolite paracetamol See also EditBex compound analgesic References Edit DR H J Clayton The Sydney Morning Herald NSW National Library of Australia 1 November 1928 p 12 Retrieved 16 August 2014 a b c In Equity The Sydney Morning Herald National Library of Australia 18 May 1934 p 7 Retrieved 16 August 2014 Advertising The Australian Women s Weekly National Library of Australia 31 October 1951 p 63 Retrieved 18 August 2014 Advertising The Australian Women s Weekly National Library of Australia 14 March 1936 p 18 Retrieved 18 August 2014 Vincent s A P C Newcastle Morning Herald and Miners Advocate National Library of Australia 25 February 1938 p 7 Retrieved 18 August 2014 Advertising Newcastle Morning Herald and Miners Advocate National Library of Australia 27 September 1941 p 4 Retrieved 18 August 2014 An early illustrated advertisement Advertising The Australian Women s Weekly National Library of Australia 2 August 1972 p 20 Retrieved 18 August 2014 The Kidney chapter 13 Analgesic nephropathy PDF Morrow Claire 1 October 2009 The dangers of self medicating mother s little helpers don t always have a desirable effect warns Claire Morrow Feel Life Health Investigate Howling at the Moon Publishing Ltd 9 105 76 2 ISSN 1832 2794 Stressful Day What you need is a cup of tea a Bex and a good lie down So the advertising went in the days of powders When I worked in aged care it was not uncommon to come across an elderl Bex Powders School of Medical Sciences UNSW Retrieved 15 June 2018 Dunlevy Sue 29 August 2014 Cancer Council NSW Bex powder killed more than pain news com au News Corp Australian Network Retrieved 31 March 2018 Retrieved from https en wikipedia org w index php title Vincent Chemical Co amp oldid 1100307505, wikipedia, wiki, book, books, library,
