Vesnarinone (INN) is a cardiotonic agent.[1] A mixed phosphodiesterase 3 inhibitor and ion-channel modifier that has modest, dose-dependent, positive inotropic activity, but minimal negative chronotropic activity. Vesnarinone improves ventricular performance most in patients with the worst degree of heart failure.
^Cavusoglu E, Frishman WH, Klapholz M (June 1995). "Vesnarinone: a new inotropic agent for treating congestive heart failure". Journal of Cardiac Failure. 1 (3): 249–257. doi:10.1016/1071-9164(95)90030-6. PMID 9420657.
vesnarinone, cardiotonic, agent, mixed, phosphodiesterase, inhibitor, channel, modifier, that, modest, dose, dependent, positive, inotropic, activity, minimal, negative, chronotropic, activity, improves, ventricular, performance, most, patients, with, worst, d. Vesnarinone INN is a cardiotonic agent 1 A mixed phosphodiesterase 3 inhibitor and ion channel modifier that has modest dose dependent positive inotropic activity but minimal negative chronotropic activity Vesnarinone improves ventricular performance most in patients with the worst degree of heart failure VesnarinoneClinical dataAHFS Drugs comInternational Drug NamesRoutes ofadministrationBy mouthATC codeNoneLegal statusLegal statusIn general Prescription only IdentifiersIUPAC name 6 4 3 4 Dimethoxybenzoyl piperazin 1 yl 3 4 dihydro 1H quinolin 2 oneCAS Number81840 15 5 YPubChem CID5663ChemSpider5461 NUNII5COW40EV8MChEMBLChEMBL17423 NCompTox Dashboard EPA DTXSID80231411Chemical and physical dataFormulaC 22H 25N 3O 4Molar mass395 459 g mol 13D model JSmol Interactive imageSMILES COC1 C C C C C1 C O N2CCN CC2 C3 CC4 C C C3 NC O CC4 OCInChI InChI 1S C22H25N3O4 c1 28 19 7 3 16 14 20 19 29 2 22 27 25 11 9 24 10 12 25 17 5 6 18 15 13 17 4 8 21 26 23 18 h3 5 7 13 14H 4 8 12H2 1 2H3 H 23 26 NKey ZVNYJIZDIRKMBF UHFFFAOYSA N N N Y what is this verify References edit Cavusoglu E Frishman WH Klapholz M June 1995 Vesnarinone a new inotropic agent for treating congestive heart failure Journal of Cardiac Failure 1 3 249 257 doi 10 1016 1071 9164 95 90030 6 PMID 9420657 External links edit nbsp Media related to Vesnarinone at Wikimedia Commons nbsp This drug article relating to the cardiovascular system is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Vesnarinone amp oldid 1134910955, wikipedia, wiki, book, books, library,