This gene encodes a protein belonging to the vacuolar-protein-sorting-13 gene family. In yeast, vacuolar-protein-sorting-13 proteins are involved in trafficking of membrane proteins between the trans-Golgi network and the prevacuolar compartment.
While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode distinct isoforms.[5]
Referencesedit
^ abcGRCh38: Ensembl release 89: ENSG00000048707 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000020220 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ab"Entrez Gene: VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)".
Further readingedit
Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Seki N, Ohira M, Nagase T, et al. (1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–9. doi:10.1093/dnares/4.5.345. PMID 9455484.
Nakayama M, Kikuno R, Ohara O (2003). "Protein–Protein Interactions Between Large Proteins: Two-Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMC187542. PMID 12421765.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC528928. PMID 15489334.
Velayos-Baeza A, Vettori A, Copley RR, et al. (2005). "Analysis of the human VPS13 gene family". Genomics. 84 (3): 536–49. doi:10.1016/j.ygeno.2004.04.012. PMID 15498460.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
This article on a gene on human chromosome 1 is a stub. You can help Wikipedia by expanding it.
vps13d, vacuolar, protein, sorting, associated, protein, protein, that, humans, encoded, gene, identifiersaliases, vacuolar, protein, sorting, homolog, scar4external, idsomim, 608877, 2448530, homologene, 15583, genecards, gene, location, human, chromosome, hu. Vacuolar protein sorting associated protein 13D is a protein that in humans is encoded by the VPS13D gene 5 VPS13DIdentifiersAliasesVPS13D vacuolar protein sorting 13 homolog D SCAR4External IDsOMIM 608877 MGI 2448530 HomoloGene 15583 GeneCards VPS13DGene location Human Chr Chromosome 1 human 1 Band1p36 22 p36 21Start12 230 030 bp 1 End12 512 047 bp 1 Gene location Mouse Chr Chromosome 4 mouse 2 Band4 4 E1Start144 699 192 bp 2 End144 921 575 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inskin of abdomensural nerveleft ventricleright lobe of thyroid glandleft lobe of thyroid glandcanal of the cervixtendongastrocnemius muscleAchilles tendonleft coronary arteryTop expressed inhandotolith organutricleesophagusthymusfootsuperior frontal gyrusadrenal glandjejunumbrown adipose tissueMore reference expression dataBioGPSMore reference expression dataOrthologsSpeciesHumanMouseEntrez55187230895EnsemblENSG00000048707ENSMUSG00000020220UniProtQ5THJ4n aRefSeq mRNA NM 018156NM 015378NM 001033190NM 001128198NM 001276465NM 001276502RefSeq protein NP 056193NP 060626n aLocation UCSC Chr 1 12 23 12 51 MbChr 4 144 7 144 92 MbPubMed search 3 4 WikidataView Edit HumanView Edit Mouse This gene encodes a protein belonging to the vacuolar protein sorting 13 gene family In yeast vacuolar protein sorting 13 proteins are involved in trafficking of membrane proteins between the trans Golgi network and the prevacuolar compartment While several transcript variants may exist for this gene the full length natures of only two have been described to date These two represent the major variants of this gene and encode distinct isoforms 5 References edit a b c GRCh38 Ensembl release 89 ENSG00000048707 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000020220 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine a b Entrez Gene VPS13D vacuolar protein sorting 13 homolog D S cerevisiae Further reading editAndersson B Wentland MA Ricafrente JY et al 1996 A double adaptor method for improved shotgun library construction Anal Biochem 236 1 107 13 doi 10 1006 abio 1996 0138 PMID 8619474 Yu W Andersson B Worley KC et al 1997 Large Scale Concatenation cDNA Sequencing Genome Res 7 4 353 8 doi 10 1101 gr 7 4 353 PMC 139146 PMID 9110174 Seki N Ohira M Nagase T et al 1998 Characterization of cDNA clones in size fractionated cDNA libraries from human brain DNA Res 4 5 345 9 doi 10 1093 dnares 4 5 345 PMID 9455484 Nakayama M Kikuno R Ohara O 2003 Protein Protein Interactions Between Large Proteins Two Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs Genome Res 12 11 1773 84 doi 10 1101 gr 406902 PMC 187542 PMID 12421765 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Gerhard DS Wagner L Feingold EA et al 2004 The Status Quality and Expansion of the NIH Full Length cDNA Project The Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Velayos Baeza A Vettori A Copley RR et al 2005 Analysis of the human VPS13 gene family Genomics 84 3 536 49 doi 10 1016 j ygeno 2004 04 012 PMID 15498460 Gregory SG Barlow KF McLay KE et al 2006 The DNA sequence and biological annotation of human chromosome 1 Nature 441 7091 315 21 Bibcode 2006Natur 441 315G doi 10 1038 nature04727 PMID 16710414 nbsp This article on a gene on human chromosome 1 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title VPS13D amp oldid 1115491400, wikipedia, wiki, book, books, library,
