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Wikipedia

Trimazosin

Trimazosin is a sympatholytic alpha-1 blocker.[1][2]

Trimazosin
Clinical data
ATC code
Identifiers
  • (2-Hydroxy-2-methylpropyl) 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate
CAS Number
  • 35795-16-5 Y
  • HCl: 53746-46-6 Y
PubChem CID
  • 37264
ChemSpider
  • 34203 N
UNII
  • 31L760807H
  • HCl: 827T79ILE7 Y
KEGG
  • D08212 N
ChEMBL
  • ChEMBL513301 N
CompTox Dashboard (EPA)
  • DTXSID50189319
ECHA InfoCard100.047.924
Chemical and physical data
FormulaC20H29N5O6
Molar mass435.481 g·mol−1
3D model (JSmol)
  • Interactive image
  • O=C(OCC(O)(C)C)N3CCN(c1nc(N)c2c(n1)c(OC)c(OC)c(OC)c2)CC3
  • InChI=1S/C20H29N5O6/c1-20(2,27)11-31-19(26)25-8-6-24(7-9-25)18-22-14-12(17(21)23-18)10-13(28-3)15(29-4)16(14)30-5/h10,27H,6-9,11H2,1-5H3,(H2,21,22,23) N
  • Key:YNZXWQJZEDLQEG-UHFFFAOYSA-N N
 NY (what is this?)  (verify)

References edit

  1. ^ van Kalken CK, van der Meulen J, Oe PL, Vriesendorp R, Donker AJ (1986). "Pharmacokinetics of trimazosin and its effects on blood pressure, renal function and proteinuria during short-term therapy of patients with impaired renal function and hypertension". Eur. J. Clin. Pharmacol. 31 (1): 63–8. doi:10.1007/BF00870988. PMID 3780829. S2CID 19123951.
  2. ^ U.S. patent 3,669,968



trimazosin, sympatholytic, alpha, blocker, clinical, dataatc, codec02ca03, identifiersiupac, name, hydroxy, methylpropyl, amino, trimethoxyquinazolin, piperazine, carboxylatecas, number35795, yhcl, 53746, ypubchem, cid37264chemspider34203, nunii31l760807hhcl, . Trimazosin is a sympatholytic alpha 1 blocker 1 2 TrimazosinClinical dataATC codeC02CA03 WHO IdentifiersIUPAC name 2 Hydroxy 2 methylpropyl 4 4 amino 6 7 8 trimethoxyquinazolin 2 yl piperazine 1 carboxylateCAS Number35795 16 5 YHCl 53746 46 6 YPubChem CID37264ChemSpider34203 NUNII31L760807HHCl 827T79ILE7 YKEGGD08212 NChEMBLChEMBL513301 NCompTox Dashboard EPA DTXSID50189319ECHA InfoCard100 047 924Chemical and physical dataFormulaC 20H 29N 5O 6Molar mass435 481 g mol 13D model JSmol Interactive imageSMILES O C OCC O C C N3CCN c1nc N c2c n1 c OC c OC c OC c2 CC3InChI InChI 1S C20H29N5O6 c1 20 2 27 11 31 19 26 25 8 6 24 7 9 25 18 22 14 12 17 21 23 18 10 13 28 3 15 29 4 16 14 30 5 h10 27H 6 9 11H2 1 5H3 H2 21 22 23 NKey YNZXWQJZEDLQEG UHFFFAOYSA N N N Y what is this verify References edit van Kalken CK van der Meulen J Oe PL Vriesendorp R Donker AJ 1986 Pharmacokinetics of trimazosin and its effects on blood pressure renal function and proteinuria during short term therapy of patients with impaired renal function and hypertension Eur J Clin Pharmacol 31 1 63 8 doi 10 1007 BF00870988 PMID 3780829 S2CID 19123951 U S patent 3 669 968 nbsp This antihypertensive related article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Trimazosin amp oldid 1107916922, wikipedia, wiki, book, books, library,

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