Technetium (99mTc) tilmanocept, trade name Lymphoseek, is a radiopharmaceutical diagnostic imaging agent used to locate lymph nodes which may be draining from tumors, and assist doctors in locating lymph nodes for removal during surgery.[6]
^"Lymphoseek kit for the preparation of technetium [99m Tc] tilmanocept injection vial". Therapeutic Goods Administration (TGA). Retrieved 28 October 2020.
^"Summary for ARTG Entry: 296337 Lymphoseek kit for the preparation of technetium [99m Tc] tilmanocept injection vial" (PDF). Therapeutic Goods Administration (TGA). Retrieved 28 October 2020.
^"Lymphoseek 50 micrograms kit for radiopharmaceutical preparation - Summary of Product Characteristics (SmPC)". (emc). 18 May 2020. Retrieved 28 October 2020.
^ abc"Kit for the preparation of Lymphoseek (technetium tc 99m tilmanocept)- tilmanocept kit". DailyMed. 8 July 2019. Retrieved 28 October 2020.
^Marcinow AM, Hall N, Byrum E, Teknos TN, Old MO, Agrawal A (September 2013). "Use of a novel receptor-targeted (CD206) radiotracer, 99mTc-tilmanocept, and SPECT/CT for sentinel lymph node detection in oral cavity squamous cell carcinoma: initial institutional report in an ongoing phase 3 study". JAMA Otolaryngology–Head & Neck Surgery. 139 (9): 895–902. doi:10.1001/jamaoto.2013.4239. PMC4301415. PMID 24051744.
^ ab (Press release). U.S. Food and Drug Administration (FDA). 13 March 2013. Archived from the original on 30 March 2014.
External linksedit
"Technetium Tc 99m Tilmanocept". Drug Information Portal. U.S. National Library of Medicine.
technetium, 99mtc, tilmanocept, trade, name, lymphoseek, radiopharmaceutical, diagnostic, imaging, agent, used, locate, lymph, nodes, which, draining, from, tumors, assist, doctors, locating, lymph, nodes, removal, during, surgery, clinical, datatrade, namesly. Technetium 99mTc tilmanocept trade name Lymphoseek is a radiopharmaceutical diagnostic imaging agent used to locate lymph nodes which may be draining from tumors and assist doctors in locating lymph nodes for removal during surgery 6 Technetium 99mTc tilmanoceptClinical dataTrade namesLymphoseekAHFS Drugs comMicromedex Detailed Consumer InformationLicense dataUS DailyMed TilmanoceptPregnancycategoryAU CRoutes ofadministrationIntradermal subcutaneous intratumorATC codeV09IA09 WHO Legal statusLegal statusAU S4 Prescription only 1 2 amp UK POM Prescription only 3 US only 4 EU Rx only 5 Pharmacokinetic dataElimination half life1 75 to 3 05 hours at injection siteIdentifiersIUPAC name Dextran 3 2 aminoethyl thio propyl 17 carboxy 10 13 16 tris carboxymethyl 8 oxo 4 thia 7 10 13 16 tetraazaheptadec 1 yl 3 2 1 imino 2 D mannopyranosylthio ethyl amino ethyl thio propyl ether technetium 99m complexesCAS Number1262984 82 6 YUNII8IHI69PQTCKEGGD11543Chemical and physical dataFormula C6H10O5 n C19H28N4O9S99mTc 3 8 C13H24N2O5S2 12 20 C5H11NS 0 17Molar mass15 281 23 454 g mol 4 The most common side effects identified in clinical trials was pain or irritation at the injection site 7 It was approved by the U S Food and Drug Administration FDA in March 2013 for the imaging of lymph nodes 4 7 References edit Lymphoseek kit for the preparation of technetium 99m Tc tilmanocept injection vial Therapeutic Goods Administration TGA Retrieved 28 October 2020 Summary for ARTG Entry 296337 Lymphoseek kit for the preparation of technetium 99m Tc tilmanocept injection vial PDF Therapeutic Goods Administration TGA Retrieved 28 October 2020 Lymphoseek 50 micrograms kit for radiopharmaceutical preparation Summary of Product Characteristics SmPC emc 18 May 2020 Retrieved 28 October 2020 a b c Kit for the preparation of Lymphoseek technetium tc 99m tilmanocept tilmanocept kit DailyMed 8 July 2019 Retrieved 28 October 2020 Lymphoseek EPAR European Medicines Agency EMA 17 September 2018 Retrieved 28 October 2020 Marcinow AM Hall N Byrum E Teknos TN Old MO Agrawal A September 2013 Use of a novel receptor targeted CD206 radiotracer 99mTc tilmanocept and SPECT CT for sentinel lymph node detection in oral cavity squamous cell carcinoma initial institutional report in an ongoing phase 3 study JAMA Otolaryngology Head amp Neck Surgery 139 9 895 902 doi 10 1001 jamaoto 2013 4239 PMC 4301415 PMID 24051744 a b FDA approves Lymphoseek to help locate lymph nodes in patients with certain cancers Press release U S Food and Drug Administration FDA 13 March 2013 Archived from the original on 30 March 2014 External links edit Technetium Tc 99m Tilmanocept Drug Information Portal U S National Library of Medicine Portal nbsp Medicine nbsp This pharmacology related article is a stub You can help Wikipedia by expanding it vte nbsp This medical diagnostic article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Technetium 99mTc tilmanocept amp oldid 1182785389, wikipedia, wiki, book, books, library,
