Tachosil may cause an allergic reaction, thrombosis (blood clots), a blockage in the intestine when used during abdominal surgeries, the formation of scar tissue and foreign body granuloma (a type of inflammatory reaction).[4]
Medical usesedit
Tachosil is indicated in for supportive treatment in surgery for improvement of haemostasis, to promote tissue sealing and for suture support in vascular surgery where standard techniques are insufficient.[4] According to studies comparing Tachosil to argon beamer or stitching in patients undergoing liver surgery, Tachosil was associated with significantly lower time until the bleeding stopped.[1] Tachosil is indicated in adults for supportive sealing of the dura mater to prevent postoperative cerebrospinal leakage following neurological surgery.[4]
Referencesedit
^. (emc). 31 January 2020. Archived from the original on 10 July 2020. Retrieved 9 July 2020.
^ abc"Tachosil- thrombin human and fibrinogen patch". DailyMed. 16 February 2023. from the original on 19 May 2023. Retrieved 19 May 2023.
^"Tachosil- thrombin human and fibrinogen patch". DailyMed. 2 November 2022. from the original on 19 May 2023. Retrieved 19 May 2023.
^ abcde"TachoSil EPAR". European Medicines Agency (EMA). 17 September 2018. from the original on 13 July 2020. Retrieved 9 July 2020. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
^Colombo GL, Bettoni D, Di Matteo S, Grumi C, Molon C, Spinelli D, et al. (2014). "Economic and outcomes consequences of Tachosil: a systematic review". Vascular Health and Risk Management. 10: 569–75. doi:10.2147/VHRM.S63199. PMC4166367. PMID 25246797.
tachosil, tachosil, equine, collagen, sponge, coated, with, human, plasma, derived, coagulation, factors, fibrinogen, thrombin, used, during, surgery, stop, local, bleeding, internal, organs, hemostasis, tachosil, reacts, upon, contact, with, blood, other, bod. Tachosil is an equine collagen sponge coated with the human plasma derived coagulation factors fibrinogen and thrombin 2 5 It is used during surgery to stop local bleeding on internal organs hemostasis 2 Tachosil reacts upon contact with blood other body fluids or saline to form a clot that glues it to the tissue surface 4 TachoSilCombination ofFibrinogenGlycoproteinThrombinCoagulation factorClinical dataTrade namesTachosilAHFS Drugs comProfessional Drug FactsLicense dataUS DailyMed TachosilRoutes ofadministrationEpilesionalATC codeB02BC30 WHO Legal statusLegal statusUK POM Prescription only 1 US only 2 3 EU Rx only 4 IdentifiersKEGGD12591 Tachosil may cause an allergic reaction thrombosis blood clots a blockage in the intestine when used during abdominal surgeries the formation of scar tissue and foreign body granuloma a type of inflammatory reaction 4 Medical uses editTachosil is indicated in for supportive treatment in surgery for improvement of haemostasis to promote tissue sealing and for suture support in vascular surgery where standard techniques are insufficient 4 According to studies comparing Tachosil to argon beamer or stitching in patients undergoing liver surgery Tachosil was associated with significantly lower time until the bleeding stopped 1 Tachosil is indicated in adults for supportive sealing of the dura mater to prevent postoperative cerebrospinal leakage following neurological surgery 4 References edit TachoSil sealant matrix Summary of Product Characteristics SmPC emc 31 January 2020 Archived from the original on 10 July 2020 Retrieved 9 July 2020 a b c Tachosil thrombin human and fibrinogen patch DailyMed 16 February 2023 Archived from the original on 19 May 2023 Retrieved 19 May 2023 Tachosil thrombin human and fibrinogen patch DailyMed 2 November 2022 Archived from the original on 19 May 2023 Retrieved 19 May 2023 a b c d e TachoSil EPAR European Medicines Agency EMA 17 September 2018 Archived from the original on 13 July 2020 Retrieved 9 July 2020 Text was copied from this source which is copyright European Medicines Agency Reproduction is authorized provided the source is acknowledged Colombo GL Bettoni D Di Matteo S Grumi C Molon C Spinelli D et al 2014 Economic and outcomes consequences of Tachosil a systematic review Vascular Health and Risk Management 10 569 75 doi 10 2147 VHRM S63199 PMC 4166367 PMID 25246797 Portal nbsp Medicine nbsp This drug article relating to the blood and blood forming organs is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title TachoSil amp oldid 1225543385, wikipedia, wiki, book, books, library,
