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Wikipedia

TOE1

Target of EGR1 protein 1 is a protein that in humans is encoded by the TOE1 gene.[5][6]

TOE1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTOE1, hCaf1z, target of EGR1, member 1 (nuclear), PCH7, target of EGR1, exonuclease, TOE-1
External IDsOMIM: 613931 MGI: 1915526 HomoloGene: 11823 GeneCards: TOE1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_025077

NM_026654

RefSeq (protein)

NP_079353

NP_080930

Location (UCSC)Chr 1: 45.34 – 45.34 MbChr 4: 116.65 – 116.66 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References Edit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000132773 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028688 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ De Belle I, Wu JX, Sperandio S, Mercola D, Adamson ED (Apr 2003). "In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr1". J Biol Chem. 278 (16): 14306–12. doi:10.1074/jbc.M210502200. PMID 12562764.
  6. ^ "Entrez Gene: TOE1 target of EGR1, member 1 (nuclear)".

Further reading Edit

  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Will CL, Schneider C, Hossbach M, et al. (2004). "The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome". RNA. 10 (6): 929–41. doi:10.1261/rna.7320604. PMC 1370585. PMID 15146077.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, et al. (1995). "Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening". Genomics. 23 (1): 42–50. doi:10.1006/geno.1994.1457. PMID 7829101.

toe1, target, egr1, protein, protein, that, humans, encoded, gene, available, structurespdbortholog, search, pdbe, rcsblist, codes2fc6identifiersaliases, hcaf1z, target, egr1, member, nuclear, pch7, target, egr1, exonuclease, 1external, idsomim, 613931, 191552. Target of EGR1 protein 1 is a protein that in humans is encoded by the TOE1 gene 5 6 TOE1Available structuresPDBOrtholog search PDBe RCSBList of PDB id codes2FC6IdentifiersAliasesTOE1 hCaf1z target of EGR1 member 1 nuclear PCH7 target of EGR1 exonuclease TOE 1External IDsOMIM 613931 MGI 1915526 HomoloGene 11823 GeneCards TOE1Gene location Human Chr Chromosome 1 human 1 Band1p34 1Start45 340 052 bp 1 End45 343 973 bp 1 Gene location Mouse Chr Chromosome 4 mouse 2 Band4 4 D1Start116 651 507 bp 2 End116 664 837 bp 2 RNA expression patternBgeeHumanMouse ortholog Top expressed inolfactory bulbparotid glandright lobe of thyroid glandsmooth muscle tissuerectumlymph nodeleft lobe of thyroid glandspleenendothelial cellthymusTop expressed inprimitive streakrenal corpusclemorulablastocystspermatocytesuperior cervical ganglionmedullary collecting ductseminal vesiculaureterspermatidMore reference expression dataBioGPSMore reference expression dataGene ontologyMolecular function3 5 exoribonuclease activity protein binding metal ion binding nucleic acid binding poly A specific ribonuclease activity snRNA binding DNA binding transcription factor activity RNA polymerase II specificCellular componentcytoplasm Cajal body nuclear speck nucleolus nucleoplasm nucleus nuclear bodyBiological processRNA phosphodiester bond hydrolysis exonucleolytic snRNA 3 end processing regulation of transcription by RNA polymerase IISources Amigo QuickGOOrthologsSpeciesHumanMouseEntrez11403468276EnsemblENSG00000132773ENSMUSG00000028688UniProtQ96GM8Q9D2E2RefSeq mRNA NM 025077NM 026654RefSeq protein NP 079353NP 080930Location UCSC Chr 1 45 34 45 34 MbChr 4 116 65 116 66 MbPubMed search 3 4 WikidataView Edit HumanView Edit MouseReferences Edit a b c GRCh38 Ensembl release 89 ENSG00000132773 Ensembl May 2017 a b c GRCm38 Ensembl release 89 ENSMUSG00000028688 Ensembl May 2017 Human PubMed Reference National Center for Biotechnology Information U S National Library of Medicine Mouse PubMed Reference National Center for Biotechnology Information U S National Library of Medicine De Belle I Wu JX Sperandio S Mercola D Adamson ED Apr 2003 In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr1 J Biol Chem 278 16 14306 12 doi 10 1074 jbc M210502200 PMID 12562764 Entrez Gene TOE1 target of EGR1 member 1 nuclear Further reading EditOlsen JV Blagoev B Gnad F et al 2006 Global in vivo and site specific phosphorylation dynamics in signaling networks Cell 127 3 635 48 doi 10 1016 j cell 2006 09 026 PMID 17081983 Gregory SG Barlow KF McLay KE et al 2006 The DNA sequence and biological annotation of human chromosome 1 Nature 441 7091 315 21 Bibcode 2006Natur 441 315G doi 10 1038 nature04727 PMID 16710414 Kimura K Wakamatsu A Suzuki Y et al 2006 Diversification of transcriptional modulation Large scale identification and characterization of putative alternative promoters of human genes Genome Res 16 1 55 65 doi 10 1101 gr 4039406 PMC 1356129 PMID 16344560 Gerhard DS Wagner L Feingold EA et al 2004 The Status Quality and Expansion of the NIH Full Length cDNA Project The Mammalian Gene Collection MGC Genome Res 14 10B 2121 7 doi 10 1101 gr 2596504 PMC 528928 PMID 15489334 Will CL Schneider C Hossbach M et al 2004 The human 18S U11 U12 snRNP contains a set of novel proteins not found in the U2 dependent spliceosome RNA 10 6 929 41 doi 10 1261 rna 7320604 PMC 1370585 PMID 15146077 Ota T Suzuki Y Nishikawa T et al 2004 Complete sequencing and characterization of 21 243 full length human cDNAs Nat Genet 36 1 40 5 doi 10 1038 ng1285 PMID 14702039 Strausberg RL Feingold EA Grouse LH et al 2003 Generation and initial analysis of more than 15 000 full length human and mouse cDNA sequences Proc Natl Acad Sci U S A 99 26 16899 903 Bibcode 2002PNAS 9916899M doi 10 1073 pnas 242603899 PMC 139241 PMID 12477932 Robertson NG Khetarpal U Gutierrez Espeleta GA et al 1995 Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening Genomics 23 1 42 50 doi 10 1006 geno 1994 1457 PMID 7829101 This article on a gene on human chromosome 1 is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title TOE1 amp oldid 1115488244, wikipedia, wiki, book, books, library,

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