Except for TRAF7, these proteins share a relatively conserved secondary structure, including a namesake C-terminal TRAF domain that mediates interactions with other signaling components such as the transmembrane TNF receptors and CD40.
receptor, associated, factor, traf, redirects, here, school, traf, trafs, family, proteins, primarily, involved, regulation, inflammation, antiviral, responses, apoptosis, currently, seven, traf, proteins, have, been, characterized, mammals, traf1, traf2, traf. TRAF redirects here For the school see Traf TNF receptor associated factors TRAFs are a family of proteins primarily involved in the regulation of inflammation antiviral responses and apoptosis 1 Currently seven TRAF proteins have been characterized in mammals TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 and TRAF7 Except for TRAF7 these proteins share a relatively conserved secondary structure including a namesake C terminal TRAF domain that mediates interactions with other signaling components such as the transmembrane TNF receptors and CD40 See also editTumor necrosis factorsReferences edit Inoue J Ishida T Tsukamoto N Kobayashi N Naito A Azuma S Yamamoto T January 2000 Tumor necrosis factor receptor associated factor TRAF family adapter proteins that mediate cytokine signaling Exp Cell Res 254 1 14 24 doi 10 1006 excr 1999 4733 PMID 10623461 External links editTRAF Proteins at the U S National Library of Medicine Medical Subject Headings MeSH nbsp This biochemistry article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title TNF receptor associated factor amp oldid 993565796, wikipedia, wiki, book, books, library,
